1,721,115 research outputs found
Optical coherence tomography and optical coherence tomography angiography in glaucoma: diagnosis, progression, and correlation with functional tests
The present review will summarize the most updated findings with regards to optical coherence tomography and optical coherence tomography angiography in glaucoma, highlighting their clinical use for detection and monitoring of the disease, and their correlation to functional tests (such as visual field) widely employed in the asset of modern glaucoma clinics
The Effect of Aging on Nerve Morphology and Substance P Expression in Mouse and Human Corneas (vol 59, pg 5329, 2018)
When the article was first published, the authors’ names were listed with surnames first, i.e., Barbariga Marco, Rabiolo Alessandro, Fonteyne Philippe, Bignami Fabio, Rama Paolo, and Ferrari Giulio. To adhere to journal style, the online article has been corrected so that the surnames appear last: Marco Barbariga, Alessandro Rabiolo, Philippe Fonteyne, Fabio Bignami, Paolo Rama, and Giulio Ferrari. Citation: Barbariga M, Rabiolo A, Fonteyne P, Bignami F, Rama P, Ferrari G. Erratum in: The effect of aging on nerve morphology and Substance P expression in mouse and human corneas. Invest Ophthalmol Vis Sci. 2018;59:6026. https://doi.org/10.1167/iovs.18-24707a
Familial Exudative Vitreoretinopathy Imaged With Optical Coherence Tomography Angiography
The authors present a case of a 29-year-old man who presented to the Department of Ophthalmology at their institution to complete a peripheral laser treatment in his left eye for familial exudative vitreoretinopathy complicated by tractional macular edema
Comment on: The Tube Versus Trabeculectomy IRIS® Registry Study: Cohort Selection and Follow-up and Comparisons to the Randomized Controlled Trial
Correspondence: Impact of Binarization Thresholding and Brightness/Contrast Adjustment Methodology on Optical Coherence Tomography Angiography Image Quantification
Patient-reported outcome measures should not be the primary outcome in glaucoma clinical trials of disease modification
Laser goniopuncture after deep sclerectomy: incidence, long-term outcomes and risk factors for failure
Aims To report the incidence, risk factors and long-term outcomes of laser goniopuncture (LGP) in patients with previous deep sclerectomy (DS). Methods Retrospective cohort study of 1765 eyes (1385 patients) undergoing DS with or without cataract surgery between 2001 and 2020 in two UK institutions. Kaplan-Meier was used to estimate LGP incidence. DS success after LGP was calculated for criteria A, B, and C defined as intraocular pressure (IOP) of ≤18, ≤15 and ≤12 mm Hg with 20%, 25% and 30% reduction, respectively. Cox regression was used to investigate factors associated with the risk of failure. Results LGP had an estimated incidence of 33.3% (30.9%-35.6%), 56.3% (53.5%-58.9%) and 62.8% (59.7%-65.6%) at 1, 3, 5 years, respectively. Mean (±SD) IOP significantly (p<0.001) decreased from 21.2 (±6.0) mm Hg pre-LGP to 13.8 (±5.2) mm Hg and 12.9 (±4.7) mm Hg at 3 and 5 years post-LGP, respectively. Success rates at 3 and 5 years were, respectively, 40.9% (37.5%-44.6%) and 33.7% (30.3%-37.6%) for criterion A; 27.1% (24.0%-30.5%) and 22.3% (19.3%-25.7%) for criterion B and 13.9% (11.6%-16.7%) and 11.6% (9.5%-14.3%) for criterion C. In all models, higher pre-LGP IOP (p<0.001) and higher pre-LGP medication number (p<0.001) were associated with increased failure, while male gender (p≤0.004), intraoperative mitomycin C (p≤0.031), longer interval between DS and LGP (p≤0.01) with reduced failure. Conclusion Most patients undergoing DS will eventually require LGP. LGP is effective at rescuing eyes with a failing DS. This study identifies several factors associated with LGP outcomes, knowledge of which may help clinicians predict LGP success
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