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VAGAL NERVE STIMULATION : CLINICAL EXPERIENCE IN DRUG-RESISTANT PEDIATRIC EPILEPTIC PATIENTS
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Spinal epidural en-plaque meningioma with an unusual pattern of calcification in a 14-year-old girl: case report and review of the literature.
No full textVagus Nerve Stimulation (VNS) is Effective in Treating Catastrophic 1 Epilepsy in Very Young Children
No full textThe objective of this study is to evaluate the safety and efficacy of vagus nerve stimulation (VNS) in very young children suffering from catastrophic epilepsy and status epilepticus. We reviewed files of 60 VNS-implanted children at our institution and we selected six very young patients, less than 3 years old (mean age at implant 1.6 years). All patients suffered from severe cognitive impairment and catastrophic epilepsy with underlying diagnosis of hemimegalencephaly (1), hypoxic-ischemic encephalopathy (1), tuberous sclerosis complex (1), and malignant migrating partial epilepsy of infancy (3). Three patients were VNS-implanted during admission at intensive care unit (ICU) after developing life-threatening status epilepticus. The mean follow-up time was 41.6 months. The VNS was implanted using a single cervical incision. No surgery-related complications were observed. Four of six children have shown a significant, persistent improvement in seizure control (range, 60-90%). In patients with status, insertion of the vagal nerve stimulator allowed early cessation of status and discharge from ICU. Quality of life and parental satisfaction improved and for three children there was some milestone evolution. Catastrophic epilepsy in infancy can be devastating and difficult to treat with drugs and surgery. If resective surgery is inappropriate or refused, VNS can be considered as a well-tolerated and effective procedure even in toddlers affected by severe epilepsy and multiple developmental disabilities
Pure and combined endoscopic approach in the surgical treatment of third ventricle tumors.
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SURGICAL TREATMENT FOR PARKINSON’S DISEASE : FROM STEREOTACTIC ABLATIVE PROCEDURES TO CRONIC HIGH FREQUENCY DEEP BRAIN STIMULATION
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Mielopatia spondilogena cervicale: risultati in una serie di 52 pazienti trattati con approccio anteriore, posteriore e combinato.
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