1,720,982 research outputs found
Morphology and Surface Properties of Blends of Eudragit RS with Different Poly(Ethylene Glycol)s
No full text
Studies on solubility and dissolution rate of gemfibrozil after its complexation with cyclodextrins
No full textThe aim of the present work was to improve the physicochemical properties of Gem through cyclodextrin (-CD) or hydroxypropyl-cyclodextrin (HP-CD) interactions. Gemfibrozil water solubility and dissolution rate were increased by cyclodextrin complexation. The study has shown that complex formation, in 1:1 stoichiometric ratio,
was successfully obtained in aqueous solution while in
the solid state only very small interactions between drug and different cyclodextrins were revealed. The pH value, changing the ionization degree of drug molecule, influenced the complexation process, as indicated by different stability constant values obtained at various pH
Physico chemical aspects upon the dissolution behaviour of different forms of carbamazepine
No full textACTA TECHNOL. LEGIS MED
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