972 research outputs found
Outcome Predictors for Non-resective Pharyngoplasty in Obstructive Sleep Apnea-Hypopnea Syndrome
No full textStructural dynamics in the evolution of SARS-CoV-2 spike glycoprotein - deuterium uptake plots
No full textDeuterium uptake plots of HDX-MS data sets contained in "Structural dynamics in the evolution of SARS-CoV-2 spike glycoprotein"
Valeria Calvaresi*, Antoni G. Wrobel*, Joanna Toporowska, Dietmar Hammerschmid, Katie J. Doores, Richard T. Bradshaw, Ricardo B. Parsons, Donald J. Benton, Chloë Roustan, Eamonn Reading, Michael H. Malim, Steven J. Gamblin, Argyris Politis*
Nature Communications, March 2023</p
Sleep complaints and sleep breathing disorders in upper and lower obstructive lung diseases
No full textUpper and lower obstructive lung diseases can induce sleep complaints and can be part of the pathogenesis of sleep breathing disorders. In fact, the physiological changes of the pattern of respiration during sleep, added to the airways disease can lead to symptomatic worsening of rhinitis, asthma and chronic obstructive pulmonary diseases (COPD); moreover, their functional and anatomical features can lead to sleep breathing disorders such as obstructive sleep apnea syndrome (OSAS). This review highlights the abovementioned relationships and the effect of disease management on its comorbidities and the patient's quality of life. Rhinitis, asthma and COPD represent causes of sleep complaints that may be reduced with optimal management of these obstructive airways diseases. Continuous positive airway pressure (CPAP) treatment of sleep apnea needs to be tailored after optimization of the therapy of concomitant diseases, but it can often ameliorate comorbid disease
Transoral glossoepiglottopexy in the treatment of adult obstructive sleep apnoea: a surgical approach
No full textThe treatment of obstructive sleep apnoea syndrome (OSAS) is still a matter of debate; among the different therapeutic alternatives, both surgical and conservative, treatment with continuous positive airway pressure (CPAP) is considered the “gold standard”. The recent scientific literature reports that even if CPAP represents an effective solution for sleep apnoeas, 12% of patients do not benefit from its use. In most cases, primary collapse of the epiglottis is responsible for failure. We developed a surgical technique that provides a stable support to the epiglottis without influencing its function during swallowing while preserving laryngeal anatomy and physiology. The procedure we propose is based on that conceived by Monnier for children affected by laryngomalacia. We analysed a group of 20 patients who underwent glossoepiglottopexy between January 2015 and September 2016 and compared data (AHI, ODI, t90, ESS, EAT10, etc.) collected before and 6 months after surgery to demonstrate the safety and effectiveness of our glossoepiglottopexy (GEP). The results allow us to consider GEP as a valid choice to treat adults who suffer from sleep apnoeas
Barbed suspension pharyngoplasty for treatment of lateral pharyngeal wall and palatal collapse in patients affected by OSAHS
No full textPurpose: The aim of this study is to analyze the efficacy of a new modified pharyngoplasty technique with barbed sutures: barbed suspension pharyngoplasty (BSP). Methods: We enrolled patients affected by obstructive sleep apnea–hypopnea syndrome (OSAHS), having the main site of obstruction at the palatal and lateral pharyngeal walls, who refused or failed to tolerate CPAP therapy and underwent non-resective pharyngoplasty with barbed sutures between January 2014 and October 2017. Two surgical techniques with barbed sutures were used: barbed reposition pharyngoplasty (BRP) and BSP; the main characteristics of the latter are a double passage of the needle, each side, through the soft palate. Results: Forty-two patients met the study inclusion criteria and were included in the analysis. Twenty-two patients underwent BRP and 20 BSP. Patients treated with both BRP and BSP achieved significant improvement in polysomnographic parameters: AHI, ODI, t90%, and daily sleepiness tested by the ESS questionnaire (p < 0.001). There were no significant differences between groups considering gender, age, or severity of OSAHS (p > 0.05). Outcomes were also comparable (p = 0.10) in the two groups; patients who underwent BSP had successful treatment in 100% of cases, compared to 86% with BRP, with a cure rate of 40% vs. 18%. Conclusions: BSP is a novel surgical technique that is effective in treating oropharyngeal collapse and can be tailored for patients with high collapsibility of the soft palate who might benefit from the palatal stiffness given by multiple passages of the suture inside i
LA LINGUA DI LUIGI EINAUDI FRA CLASSICISMO E PATHOS
No full textL’autrice fa una lettura linguistica dei testi di Luigi Einaudi, per individuare i caratteri lessicali, stilistici e retorici degli scritti dell’economista, del divulgatore, del giornalista, del presidente della Repubblica. Su di essi ha pesato a lungo l’etichetta di scrittore nitido, ordinato, algido. In realtà, sottoponendo la sua vastissima produzione scritta a un esame ravvicinato, emerge la straordinaria capacità nell’uso di modalità linguistiche varie: solennità sintattica e affabilità colloquiale, modi popolari e invenzioni lessicali, descrizioni a forti tinte e sobrietà estrema. Valeria Della Valle, The language of Luigi Einaudi between classicism and pathos, in Luigi Einaudi: economic freedom and social cohesion, by Alfredo Gigliobianco, Rome-Bari, 2010, p. 138-154. The author makes a linguistic reading of texts by Luigi Einaudi, to identify the lexical, stylistic and rhetorical characters of the writings of the economist, the popularizer, the journalist, the President of the Italian Republic. On them has long weighed the label of a crisp, neat, icy writer. In fact, subjecting its vast production on close examination, it reveals the extraordinary ability in the use of various language modes: solemnity, friendly conversational syntactic, lexical inventions and popular modes, descriptions with bright colors and extreme simplicity
White middle-class men in Rio de Janeiro. The making of a dominant subject
No full textBased on the biographical accounts of upper-middle-class white men living in wealthy parts of Rio di Janeiro, Valeria Ribeiro Corossacz analyzes specific experiences of whiteness as they are produced at the intersection of multiple categories, in particular gender, class, and sexuality. White middle class men in Rio de Janeiro investigates what it means to be classified as a white person and a man in a society known for its valorization of racial mixing and yet deeply structured by racism, class and gender inequalities. Ribeiro Corossacz focuses on certain experiences in the men’s biographical trajectories representing moments of apprenticeship in a specific model of white, heterosexual and heteronormative middle-class masculinity and describes how these experiences are constructed as normative. This book explores how class, gender and race privilege are mutually produced and perceived by these men as “normal”. Examining instances of silence and what is left unsaid but also these men’s ability to provide precise descriptions of power relations and violent episodes, the author encourages us to observe the condition of dominant subjects as a keystone of the reproduction social discrimination
El Tlacuache Núm. 422 (2010). 422 Año 10 (2010) junio. El Tlacuache
No full textLas guerras van sobre camino de papeles: la insurrección suriana en reportes de Regeneración por Valeria C. de Pina Ravest
The Creative Heritage of Valeria Fedorovna Orlova as the Basis of Domestic Forensic Handwriting Examination
No full textThe article is dedicated to the biography and scientific creativity of an eminent scientist, Doctor of Law, professor Valeria Fedorovna Orlova (18.01.1926–18.03.2021), who devoted her life to forensic handwriting examination. The author addresses V.F. Orlova’s main theoretical works and methodologies, and textbooks created under her supervision. The article introduces the main tasks and capacities of forensic handwriting examination in our country
Reporting and narrating: Communication and storytelling in Carrión’s journalistic writing
No full textIn recent years, due to the rise of cultural productions through different media, an increase in the number of journalistic publications of hybrid texts has been observed, which results from the fusion of the narrative and informative functions. The spaces traditionally devoted to different types of journalistic texts which – apart from those merely informative, may include cultural-related and opinion articles – make possible the appearance of articles which distinguish themselves trough entailing both characteristics. Therefore, this paper analyses two articles written by J. Carrion and published in the Spanish edition of The New York Times in 2018. The articles will be scrutinised in relation to the narrative and essayistic works of the author. We illustrate some characteristics of what is generally referred to as narrative journalism, as defined by Herrscher (2012) and Casals Carro (2005), among others. This will allow us to trace a profile of the author, journalist and writer which is linked to the social environment and of his work
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