1,721,149 research outputs found
Comment on: Outcome of bariatric surgery on hypothyroidism: experience from a tertiary care center in India
No full textIl fenomeno migratorio
No full textI flussi migratori non sono omogenei. Non tutto il territorio nazionale è interessato in egual misura. Lo studio cerca di porre in risalto le peculiarità del territorio Massese con rferimento alle provenienze dal continente african
mechanism of human sperm activation by extracellular atp
No full textWe have identified the mechanism whereby extracellular ATP (ATPe) triggers the acrosome reaction in human spermatozoa. This nucleotide opens a ligand-gated ion channel expressed on the sperm plasma membrane. ATPe threshold and 50% effective concentration calculated on the total added ATPe are 0.1 and 2 mM, respectively, corresponding to a free ATP concentration (ATP4-) of 3 and 200 microM, respectively. The ATPe-gated channel is selective for monovalent cations (Na+, choline, and methylglucamine), whereas on the contrary, permeability to Ca2+ is negligible. Isosmolar replacement of extracellular Na+ with sucrose fully blocked ATPe-dependent sperm activation, thus suggesting a mandatory role for Na+ influx. These results show that human sperm express an ATPe-gated Na+ channel that might have an important role in sperm activation before egg fertilization
Postural evaluation in young skaters: effect of two proprioceptive training
Full text linkThe roller skating involves developing of motor and artistic skills from an early age. The aim was to evaluate
the effects that an ocular a podalic proprioceptive training cause to postural control and stability in a sample
of young skaters. A total of 25 skaters aged between 9 and 15 (12±2.14) divided into two groups: the eyes
group (EG) aimed at exercising visual proprioception, the feet group (FG) aimed at exercising podalic
proprioception. The participants were subject to through electronic stabilometry in static mode, open (OE)
and closed (CE) eyes, in a time T0 (pre-training) and T1 (post-training), without and with skates. The results
through the two paired t-test showed that both variables Wz (TotHz) to CE within the EG (p<.05) and Wx
(TotHz) to CE within the FG (p<.05) were statistical significance. The unpaired t-test showed that the FG
obtained a greater statistical significance than the EG for the VarVit and Wx (TotHz) variables in CE (p<.05)
and Wz (TotHz) in both CE and OE (p<.05). The two-way ANOVA found statistical significance (p<.05) on
the Wx (TotHz) variable in open/closed eyes of the FG (T0/T1). We concluded that in roller skating it could
be useful to integrate athletic training with a visual proprioceptive training.
The effect of SGLT2 inhibitors on hepatic steatosis detected by MRI-PDFF in patients with type 2 Diabetes mellitus and metabolic-associated steatotic liver disease: comment
No full textCOVID-19 and smoking habits: A smoky situation!
Full text linkDear Editor, the issues recently raised by Carratù et al. on the role of smoking/former smoking in patients hospitalized for COVID-19 all around the world as widely reported in many different published papers, are important for different reasons..
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