1,721,365 research outputs found

    La Rosa Giovanni

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    Si indaga la produzione artistica di La Rosa Giovanni, argentiere palermitano documentato nel XVIII secolo in SiciliaWe investigate the artistic production of La Rosa Giovanni, a Palermo silversmith documented in the 18th century in Sicil

    Saline or albumin for fluid resuscitation in traumatic brain injury.

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    The Saline versus Albumin Fluid Evaluation (SAFE) study investigators (Aug. 30 is- sue)1 report that in their post hoc follow-up study of patients from the SAFE study who had trau- matic brain injury (the SAFE–TBI study), resusci- tation with 4% albumin resulted in higher mor- tality at 2 years than resuscitation with saline

    PHARMACOLOGICAL PREVENTION OF POSTANESTHETIC SHIVERING

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    .We question why in their study investigating drugs for preventing postanesthetic shivering Piper et al compared placebo with dolas- etron and clonidine (1). We also wonder why they state that “a dose-response study would be scientifically important and econom- ically justified only if its side-effect profile were significantly supe- rior to that of established drugs.” We question why in their study investigating drugs for preventing postanesthetic shivering Piper et al compared placebo with dolas- etron and clonidine (1). We also wonder why they state that “a dose-response study would be scientifically important and econom- ically justified only if its side-effect profile were significantly supe- rior to that of established drugs.” We question why in their study investigating drugs for preventing postanesthetic shivering Piper et al compared placebo with dolas- etron and clonidine (1). We also wonder why they state that “a dose-response study would be scientifically important and econom- ically justified only if its side-effect profile were significantly supe- rior to that of established drugs.

    MAGNESIUM SULFATE AND NEUROPROTECTION

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    We read with great interest the article from Wilkes et al. (1) report- ing that correcting ionized plasma magnesium during cardiopul- monary bypass in patients undergoing coronary artery bypass graft- ing (CABG) reduces the risk of postoperative cardiac arrhythmia. In their article, Wilkes and colleagues mention some of the systemic effects of magnesium sulfate administration and the underlying cellular mechanisms. But they fail to mention its neuroprotective effects
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