2,988 research outputs found
The European Romani Women's Movement: The struggle for human rights
Rita Izsák discusses the International Romani Women's Network (IRWN), the first registered international umbrella organization representing Romani women of all European Romani groups. She examines how IRWN is promoting women's rights, and the connection between mainstream feminist movements and the Romani movement. Development (2009) 52, 200–207. doi:10.1057/dev.2009.9
Vita umana e/o sperimentazione animale?
Il dibattito attualissimo in materia vede da un lato un’attenzione speciale nei confronti della natura (ecosistema e diversità biologica) dall’altro la ricerca del massimo benessere per l’uomo in termini di aumento della qualità e delle aspettative di vita. La centralità dell’uomo nelle ben note rivoluzioni copernicane rischia una reazione ricollocando al centro natura ed ecosistema? Si può dimenticare l’Uomo in nome di una non meglio specificata Natura? Se si blocca la sperimentazione animale, su chi si testeranno i farmaci e le terapie? Quali prospettive alternative
La "vita di Pirro" di Plutarco: una rievocazione del primo incontro fra Greci e Romani.
La biografia plutarchea di Pirro presenta in toni favorevoli il giudizio di questo grande generale greco su Roma e si riscontra uno scambio cavalleresco tra Greci e Romani
Rita B. Stadig Correspondence
Entry is a handwritten biographical sketch of Rita Stadig author of Our Maine Heritage, a history of Maine
Plasminogen activator production in a rat model of Pneumocystis carinii pneumonae
“Plasminogen activator production in a rat model of Pneumocystis carinii pneumonae”
E. angelici, C. Contini, M. Spezzano, R. Romani, P. Carfagna, P. Serra, R. Canipari.
Microbiol. Immunol. 45 (8) pp. 605-611, 2001
Keynote Speech by Rita Palacios and Luncheon
Rita Palacios holds a Ph.D. in Spanish and is a professor of languages in the School of Liberal Studies at Conestoga College in Kitchener, Ontario. Her research examines contemporary Maya literature from a cultural and gender studies perspective. She is the author of Unwriting Maya Literature: Ts’íib as Recorded Knowledge (with Paul M. Worley).
The luncheon is free for all registered participants
Vita umana e/o sperimentazione animale?
Il dibattito attualissimo in materia vede da un lato un’attenzione speciale nei confronti della natura (ecosistema e diversità biologica) dall’altro la ricerca del massimo benessere per l’uomo in termini di aumento della qualità e delle aspettative di vita. La centralità dell’uomo nelle ben note rivoluzioni copernicane rischia una reazione ricollocando al centro natura ed ecosistema? Si può dimenticare l’Uomo in nome di una non meglio specificata Natura? Se si blocca la sperimentazione animale, su chi si testeranno i farmaci e le terapie? Quali prospettive alternative
The Potential Role of Toll-Like Receptor 4 in Mediating Dopaminergic Cell Loss and Alpha-Synuclein Expression in the Acute MPTP Mouse Model of Parkinson’s Disease
Toll-like receptors (TLRs) may have a role in Parkinson's disease (PD). In this study, we aimed at investigating the dopaminergic cell loss and alpha-synuclein (α-SYN) expression in TLR4-deficient mice (TLR4-/-) acutely exposed to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), a pharmacological PD model. TLR4 ablation restrained the number of dopaminergic neurons in the substantia nigra (SN), as assessed by tyrosine hydroxylase (TH) protein expression. Intriguingly, TLR4-/- mice showed massive α-SYN protein accumulation in the midbrain along with high α-SYN mRNA levels in cerebral cortex, striatum, hippocampus, and cerebellum. Contrary to expectations, the high levels of α-SYN do not correlate with greater dopaminergic neuronal loss. The levels of nigral α-SYN protein in TLR4-/- mice further, but not significantly, increased during MPTP treatment. Contrariwise, MPTP treatment significantly induced the mRNA expression of α-SYN in examined brain regions of WT and TLR4-/- mice. Protein levels of GATA2, a transcription factor proposed to control α-SYN gene expression, did not change in TLR4-/- mice at baseline and after MPTP treatment. These findings suggest a role for TLR4 in mediating dopaminergic cell loss and in the constitutive expression of brain α-SYN. However, further exploration is needed in order to establish the actual role of α-SYN in the relative absence of TLR4
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