1,721,061 research outputs found
Peritoneal keratin granulomas: cytohistological correlation in a case of endometrial adenocarcinomawith squamous differentiation.
No full textGranulomatous peritoneal inflammationcan be due to many aetiological factors, mostly nonneoplastic(i.e. bacterial and fungal infections, parasiticinfestations, sarcoidosis, endometriosis, Crohnsdisease, foreign body reaction due to surgical material,plant material after barium enema examination,vegetable fragments from intestinal perforation, andvernix caseosa derived from amniotic fluid) but rarelysecondary to a neoplastic process.1–3 However, peritonealkeratin granulomas (PKG) have been found tobe associated with endometrial and ⁄ or ovarian adenocarcinomawith squamous differentiation,1–6 cervicalsquamous cell carcinoma (particularly followingradiation therapy),1 endometrial atypical polypoidadenomyoma with squamous morulae3 or brokenovarian dermoid cysts.1–3 We report a case of PKGvery similar to that reported by Chen,1 in a patientwith endometrial adenocarcinoma with squamousdifferentiation, and can find no other reports investigatingthe cytohistological correlation of these raregranulomatous lesions
Histiocytic endometritis
No full textTwo cases of histiocytic endometritis are reported in two 68 and 82 year-old women. One of the cases was associated with extensive endometrioid adenocarcinoma and areas of intra-myometrial histiocytic infiltration
Human dirofilariasis due to Dirofilaria ( Nochtiella) repens: update of world literature from 1935 to 2000.
No full textFollowing on from their review of 1995 (Pampiglione et al.), the authors present an update of human cases of dirofilariasis due to Dirofilaria (Nochtiella) repens (Nematoda, Filarioidea, Onchocercidae) reported in the world literature. Cases of the parasitosis published from 1995 to 2000 are reported country by country. The essential data are presented in tabular form and the clinical, parasitological, histopathological, epidemiological features are analysed. 372 new cases spread over 25 countries are thus added to the list published in 1995. The countries most affected are Italy, Sri Lanka, some republics of the ex-Soviet Union. The age of the patients varied from 4 months to 100 years, the majority being in their 40s. There was virtually no difference in incidence between sexes. The parasite appeared most frequently in the upper half of the body, particularly in the head and ocular region and also in the upper limbs. Cases of visceral involvement are also reported. Of the various forms of human dirofilariasis, that due to D. (N.) repens is confirmed to be the most important as regards not only the number of subjects affected and the wide geographical distribution but also the variety of organs involved, notably the lungs, the male genitals and the female breast, invariably leading to a wrong diagnosis of malignant tumour. In man, the zoonosis may be described as emerging: whereas until the middle of the last century only a few dozen cases were reported, in the last 50 years the number has gradually increased to reach the present 78
Appendicitis associated with presence of Schistosoma haematobium eggs: an unusual pathology for Europe - Report of three cases
No full textThree cases of appendicitis associated with presence of Schistosoma haematobium eggs in the appendix tissue are reported. The patients (two males and one female) were all from Ghana and had immigrated to Italy a few years previously. It is difficult to attribute the cause of the appendicitis to the parasite; it is more probable that the appendicular location of the eggs occurred accidentally many years earlier in an endemic zone of the country of origin, and that recently bacterial agents were able to provoke the present appendicitis. Since it is probable that with the increase in the number of immigrants to Europe from endemic countries (sub-Saharan Africa in particular) other similar cases may occur, it is important that the surgeon and the pathologist be aware of this pathology, which has so far been considered unusual
Pitfalls and difficulties in histological diagnosis of human dirofilariasis due to Dirofilaria (Nochtiella) repens
No full textThe authors have conducted a histologic study of over 90 cases of Dirofilaria infection in man due to Dirofilaria repens, the most extensive study of its kind in the would. On the basis of their findings, they illustrate the diagnostic difficulties that may arise when regreessive phenomena I ender the parasite ́s morphologic characteristics largely or completely unrecognizable. These phenomena are due to the death of the filaria inside the inflammatory nodule weeks ol months prior to surgical removal, and to the consequent invasion of inflammatory cells. They start at the nenatode ́s natural orifices (mouth, vulva, anus, cloaca) and gradually spread throughout ifs body. In cases of difficult diagnosis, therefore, it is recommended that rite nodule be sectioned at different points comprising caudal, cephalic and middle body aspects, so as to reveal the Jew morphologic features that ale still recognizable and which may afford a correct diagnosis. The authors present examples of histologic sections in color plates in which the nematode was in an excellent state of preservation and others illustrating the full range of regressive phenomena, from slight to total disintegration of the bodily structure
Infection with Cryptosporidium hominis and reinfection with Cryptosporidium parvum in a transplanted ileum
No full textA transplanted ileum was found to be infected with Cryptosporidium hominis 6 days after transplantation. Although the infection resolved, the ileum was later found to be infected with Cryptosporidium parvum. The presence of the parasite was not always correlated with diarrhea. No other gastrointestinal symptom was ever detected. Treatment with azithromycin and paromomycin apparently failed
Human pulmonary dirofilariasis
No full textTwo new cases of human pulmonary dirofilariasis, in a 66-year-old woman and a 69-year-old man, respectively, both living in the Po valley, are described. They represent the 7th and 8th cases reported in Italy and seem to be ascribable to Dirofilaria repens, even though the poor state of preservation of the parasites did not allow the morphology of the species involved to be clearly defined. In both cases, the false clinical diagnosis of lung cancer was based on the accidental radiological discovery of a coin lesion, the nematodes being located in a pulmonary artery producing a small, roundish infarct
Cryptic infection by whipworm mimicking a sessile polyp of the colon
No full textA case of trichocephaliasis in a 70-year-old male is described. The original diagnosis, based on radiological and endoscopic findings, was of a sessile polyp of the colon. Only when a fragment of the supposed polyp was removed at biopsy and examined histologically was it revealed as a single male specimen of whipworm
Regulation of cholesterol biosynthesis in rat liver after the administration of N-2-fluorenylacetamide
No full textNo abstract availabl
Mosquito-based survey for the detection of flaviviruses and filarial nematodes in Aedes albopictus and other anthropophilic mosquitoes collected in northern Italy.
No full textIn order to optimize resources, an assay allowing the detection of several etiological agents would be useful. This paper describes a polymerase chain reaction (PCR)-based assay for the parallel detection of different pathogens in mosquitoes (Diptera: Culicidae). The assay combines the analysis of both RNA and DNA, hence allowing the detection of both flaviviruses (Flaviviridae: Flavivirus) and filarial nematodes (Spirurida: Onchocercidae). The sensitivity of diagnostic assay for both flavivirus and nematode infections was tested by means of spiked samples and resulted adequate for the purpose of screening mosquito samples. The assay was implemented to check pathogen infections in 637 mosquitoes field-collected in Romagna, northern Italy. The integrity of RNA extracted from mosquito pools was checked by control amplifications targeting the 18 S rRNA of mosquitoes. Control amplifications were successful in 118 out of 119 pools. Flavivirus RNA was not found in any of these 118 pools, whereas DNA of Dirofilaria immitis (Leidy) was detected in one pool of Aedes albopictus (Skuse)
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