1,721,361 research outputs found
Severe vascular complication after implantation of a three-piece inflatable penile prosthesis
No full textWe report a case of acute arterial ischemia and deep venous thrombosis due to compression of the external iliac vein and artery by the reservoir of a three-piece inflatable penile prosthesis. Deho' F, Henry GD, Marone EM, Sacca' A, Chiesa R, Rigatti P, and Montorsi F. Severe vascular complication after implantation of a three-piece inflatable penile prosthesis. © 2008 International Society for Sexual Medicine
The importance of the extent of pelvic-lymph-node dissection in the diagnosis of lymph-node metastases in prostate cancer
No full textThe use of wallstents in patients with benign prostatic hyperplasia.
No full textThis study was conducted to assess the clinical reliability of the prostatic Urolume Wallstent for symptomatic BPH patients. One hundred patients were treated under intravenous sedation or local anesthesia. Pre- and postoperative patient evaluation included scoring of subjective symptoms, physical examination, laboratory analysis, transrectal ultrasonography, uroflowmetry with maximum flow nomograms, intravenous pyelogram and cystourethroscopy. At the long-term follow-up the vast majority of patients showed non-obstructed voiding parameters. The most frequent complications included stent malpositioning and dislocation, and persistent irritative symptomatology. The prostatic UroLume Wallstent is a safe and effective minimally invasive procedure for carefully selected BPH patients
Anatomical Radical Retropubic Prostatectomy in Patients with a Preexisting Three-Piece Inflatable Prosthesis: A Series of Case Reports
No full textOnly few reports addressed the outcome of patients submitted to anatomical radical retropubic prostatectomy (RRP) with an indwelling inflatable penile prosthesis (IPP). To assess the feasibility and safety of RRP in patients with clinically localized prostate cancer and a previously implanted with an IPP. We evaluated the surgical parameters and the follow-up functional results in this particular patient population. Four patients previously submitted to IPP implant for severe erectile dysfunction underwent RRP for organ-confined prostate cancer. Patients' charts were carefully reviewed to investigate pre- and perioperative details. Patients were evaluated by the International Index of Erectile Function (IIEF) preoperatively and at 6 months postoperatively. Patients were then contacted to assess long-term functional and oncological outcome. The outcome of the procedures was comparable to a normal population in terms of operating time, estimated blood loss, hospitalization time, and pathological outcome. No injury to the preexisting penile implant was reported. Continence was obtained in 3 (75%) patients at catheter removal, and in 1 (25%) patient at the 1-month follow-up. No major intra- and postoperative complications were reported. All patients were able to use their prosthesis after RRP. No statistical difference in pre- and post-RRP EF domain scores was found. The presence of an IPP in patients with prostate cancer is not a contraindication to perform an anatomical RRP. Surgery can be performed safely without injuring the implant and the clinical outcome in these patients is satisfactory. Postoperative implant use is not affected by RRP. Deho' F, Salonia A, Briganti A, Zanni G, Gallina A, Rokkas K, Guazzoni G, Rigatti P, and Montorsi F. Anatomical radical retropubic prostatectomy in patients with a preexisting three-piece inflatable prosthesis: A series of case reports. J Sex Med 2009;6:578-583. OI Guazzoni, Giorgio Ferruccio/0000-0002-5713-8313; Gallina, Andrea/0000-0002-4540-956
Is Erectile Dysfunction a Reliable Proxy of General Male Health Status? The Case for the International Index of Erectile Function-Erectile Function Domain
No full textIntroduction. Erectile dysfunction (ED) has emerged progressively as a sentinel marker of cardiovascular disease (CVD). The correlation between ED and the burden arising from multiple comorbid conditions has been incompletely analyzed. Aim. Assess whether erectile function, defined with the International Index of Erectile FunctionErectile Function (IIEF-EF) domain score, is associated with health-significant comorbidities scored with the Charlson comorbidity index (CCI). Methods. Clinical and hemodynamic variables of the last 140 consecutive patients who underwent penile color Doppler ultrasonography for new-onset ED were considered. Patients were assessed with a thorough medical and sexual history. Health-significant comorbidities were scored with the CCI. Main Outcome Measure. Descriptive statistics and either linear or logistic regression models tested the association among IIEF-EF, hemodynamic parameters, and CCI, which was included in the model both as continuous and categorized variable (0 vs. =1). Results. Complete data were available for 138 patients (98.6%) (mean age 46.6 years [standard deviation 13.0]; range 2175 years). CCI was 0, 1, and =2 in 94 (68.1%), 23 (16.7%), and 21 (15.25%) patients, respectively. Of all, 35 patients (79.5%) did not have a CVD comorbidity. Mean IIEF-EF was 13.7 (9.3). ED severity was no ED, mild, mild to moderate, moderate, and severe in 12 (9.1%), 28 (20.2%), 12 (9.1%), 23 (16.2%), and 63 (45.5%) patients, respectively. At multivariable linear regression analysis, CCI significantly worsened with increased age (beta = 0.33; P = 0.001) and decreased IIEF-EF values (beta = -0.25; P = 0.01). At logistic regression analysis, age (odds ratio [OR]: 1.05; P = 0.004) and IIEF-EF (OR: 0.95; P = 0.04) emerged as significant predictors of categorized CCI. Conclusions. Severity of ED, as objectively interpreted with IIEF-EF, accounts for a higher CCI, which may be considered a reliable proxy of a lower general male health status regardless of the etiology of ED. Salonia A, Castagna G, Sacca A, Ferrari M, Capitanio U, Castiglione F, Rocchini L, Briganti A, Rigatti P, and Montorsi F. Is erectile dysfunction a reliable proxy of general male health status? The case for the International Index of Erectile FunctionErectile function domain. J Sex Med **;**:****
Delay in Seeking Medical Help in Patients with New-Onset Erectile Dysfunction Remained High Over and Despite the PDE5 Era-An Ecological Study
No full textIntroduction. It is common knowledge among researchers that erectile dysfunction (ED) is an important sentinel marker of cardiovascular and overall men's health. Aim. Determine whether the delay of time between ED onset and seeking medical help (DSH), considered as a proxy of awareness of the importance of ED for overall men's health, has shortened during the phosphodiesterase type 5 inhibitors (PDE5) era. Methods. Complete data from 619 patients seeking first medical help for new-onset ED as their primary disorder between July 2000 and July 2010 were analyzed (i.e., DSH, ED severity as defined by the International Index of Erectile Function-erectile function [IIEF-EF] domain score, patient's awareness of any PDE5, and Charlson Comorbidity Index [CCI]). Analysis of variance tested DSH throughout the 10-year time frame. Cox regression models tested the association between predictors and DSH. Main Outcome Measures. Assess if DSH has shortened throughout PDE5 era. Evaluate potential predictors of DSH. Results. Overall, mean DSH was 30.2 months (median 12.0; range 5-300 months). DSH shortened throughout the analyzed 10-year period (F = 1.918; P = 0.047), with a significant drop only from year 2009 (DSH up to year 2008 vs. from year 2009: 31.0 months [12.0] vs. 7.5 months [6.0], respectively; P < 0.001). Age, CCI, educational status, and ED severity did not significantly change over time. As a whole, 560 patients (90.5%) were aware of PDE5 at the time of their first office visit. PDE5 awareness emerged as an univarible and multivariable predictor of a shortened DSH. Conversely, DSH was not clearly associated with age, CCI, educational status, or ED severity. Conclusions. Delay in seeking medical help in new-onset ED patients remained high over the PDE5 era, with a significant drop only from the year 2009. PDE5 awareness emerged as an independent predictor of shortening of this delay. Salonia A, Ferrari M, Sacca A, Pellucchi F, Castagna G, Clementi MC, Matloob R, Briganti A, Rigatti P, and Montorsi F. Delay in seeking medical help in patients with new-onset erectile dysfunction remained high over and despite the PDE5 era-An ecological study. J Sex Med 2012;9:3239-3246.Introduction: It is common knowledge among researchers that erectile dysfunction (ED) is an important sentinel marker of cardiovascular and overall men's health. Aim: Determine whether the delay of time between ED onset and seeking medical help (DSH), considered as a proxy of awareness of the importance of ED for overall men's health, has shortened during the phosphodiesterase type 5 inhibitors (PDE5) era. Methods: Complete data from 619 patients seeking first medical help for new-onset ED as their primary disorder between July 2000 and July 2010 were analyzed (i.e., DSH, ED severity as defined by the International Index of Erectile Function-erectile function [IIEF-EF] domain score, patient's awareness of any PDE5, and Charlson Comorbidity Index [CCI]). Analysis of variance tested DSH throughout the 10-year time frame. Cox regression models tested the association between predictors and DSH. Main Outcome Measures: Assess if DSH has shortened throughout PDE5 era. Evaluate potential predictors of DSH. Results: Overall, mean DSH was 30.2 months (median 12.0; range 5-300 months). DSH shortened throughout the analyzed 10-year period (F=1.918; P=0.047), with a significant drop only from year 2009 (DSH up to year 2008 vs. from year 2009: 31.0 months [12.0] vs. 7.5 months [6.0], respectively; P<0.001). Age, CCI, educational status, and ED severity did not significantly change over time. As a whole, 560 patients (90.5%) were aware of PDE5 at the time of their first office visit. PDE5 awareness emerged as an univarible and multivariable predictor of a shortened DSH. Conversely, DSH was not clearly associated with age, CCI, educational status, or ED severity. Conclusions: Delay in seeking medical help in new-onset ED patients remained high over the PDE5 era, with a significant drop only from the year 2009. PDE5 awareness emerged as an independent predictor of shortening of this delay. Salonia A, Ferrari M, Saccà A, Pellucchi F, Castagna G, Clementi MC, Matloob R, Briganti A, Rigatti P, and Montorsi F. Delay in seeking medical help in patients with new-onset erectile dysfunction remained high over and despite the PDE5 era-An ecological study. © 2012 International Society for Sexual Medicine
Primary and Pure Neuroendocrine Tumor of the Prostate
No full textPrimary neuroendocrine tumors of the prostate are very rare and their biologic behaviour is not yet well known. Clinical and histopathologic features of two cases, one with lymph-node involvement and one organ-confined are described. Young age, clinical presentation and good outcome after radical retropubic prostatectomy were comparable in both patients. © 2003 Elsevier B.V. All rights reserved
Symptomatic treatment of benign prostatic obstruction with nicergoline: a placebo controlled clinical study and urodynamic evaluation
No full textLocally induced hyperthermia in bladder cancer. In Bladder Cancer. Biology, Diagnosis and Management
No full text- …
