1,721,267 research outputs found
Trace metals and antioxidant mechanisms in gills and digestive gland of the Mediterranean mussel Mytilus galloprovincialis.
No full textTotal Oxyradical Scavenging Capacity (TOSC) in polluted and translocated mussels: a predictive biomarker of oxidative stress
No full textTotal Oxyradical Scavenging Capacity as an index of susceptibility to oxidative stress in marine organisms.
No full textThe Biological Effects of Pharmaceuticals in the Marine Environment
Full text linkEnvironmental pharmaceuticals represent a threat of emerging concern for marine ecosystems. Widely distributed and bioaccumulated, these contaminants could provoke adverse effects on aquatic organisms through modes of action like those reported for target species. In contrast to pharmacological uses, organisms in field conditions are exposed to complex mixtures of compounds with similar, different, or even opposing therapeutic effects. This review summarizes current knowledge of the main cellular pathways modulated by the most common classes of environmental pharmaceuticals occurring in marine ecosystems and accumulated by nontarget species-including nonsteroidal anti-inflammatory drugs, psychiatric drugs, cardiovascular and lipid regulator agents, steroidal hormones, and antibiotics-and describes an intricate network of possible interactions with both synergistic and antagonistic effects on the same cellular targets and metabolic pathways. This complexity reveals the intrinsic limits of the single-chemical approach to predict the long-term consequences and future impact of pharmaceuticals at organismal, population, and community levels
Mytilus galloprovincialis as bioindicator of lead pollution: biological variables and cellular responses.
No full textSeasonal variability of oxidative biomarkers, lysosomal parameters, metallothioneins and peroxisomal enzymes in the Mediterranean mussel Mytilus galloprovincialis from Adriatic Sea.
No full textBioavailability of "biologically detoxified" lead: risks arising from consumption of polluted mussels.
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