1,720,981 research outputs found
Curcumin and liver disease
No full textLiver diseases pose a major medical problem worldwide and
a wide variety of herbs have been studied for the
management of liver-related diseases. In this respect,
curcumin has long been used in traditional medicine, and in
recent years it has been the object of increasing research
interest. In combating liver diseases, it seems clear that
curcumin exerts a hypolipidic effect, which prevents the
fatty acid accumulation in the hepatocytes that may result
from metabolic imbalances, and which may cause
nonalcoholic steatohepatitis. Another crucial protective
activity of curcumin, not only in the context of chronic liver
diseases but also regarding carcinogenesis and other agerelated processes, is its potent antioxidant activity, which
affects multiple processes and signaling pathways. The
effects of curcumin on NF-jb are crucial to our
understanding of the potent hepatoprotective role of this
herb-derived micronutrient. Because curcumin is a
micronutrient that is closely related to cellular redox
balance, its properties and activity give rise to a series of
molecular reactions that in every case and biological
situation affect the mitochondria
Effect of supplementation with an extract of curcuma longa on plasma coenzyme Q10 levels during the development of experimental atherosclerosis in rabbits
No full textStructural damage induced by peroxidation may account for functional impairment of heavy synaptic mitochondria
No full textOxidative stress status in liver mitochondria and lymphocyte DNA damage of atherosclerotic rabbits supplemented with water soluble coenzyme Q10.
No full textVirgin olive oil minor components as natural drugs for the treatment of breast cancer: preliminary experiments on squalene
No full textPeriodontitis is associated with altered plasma fatty acids and cardiovascular risk markers.
No full textCoenzyme Q concentration and total antioxidant capacity of human milk at different stages of lactation in mothers of preterm and full-term infants.
No full textVirgin olive oil, compared with sunflower oil, improves longevity in rats feed lifelong on normolipidic diets
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