1,721,218 research outputs found

    Whole-Body FDG PET Imaging in Oncology

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    This manual presents a large collection of clinical cases in oncology with accompanying whole-body FDG PET-CT scans. The aim is to promote an integrated approach to the use of PET-CT, and detailed attention is therefore paid to the clinical history and diagnostic question. A central aspect of every clinical case described in this manual is the guidance on the clinical report, which is the official tool for communicating with both the referring physician and the person undergoing the diagnostic test; for this reason it needs to be clear, understandable, and written in SHARED language. The advice regarding report preparation is strongly supported by informative PET, CT, and PET-CT fused images of each disease. The book is broadly structured according to anatomic region, and a wide range of common diseases likely to be imaged using PET-CT is covered. This book will be of value to all those training or working in the field of oncology who wish to ensure that they are best placed to contextualize, interpret, and report the findings obtained with PET-CT, which can have such a dramatic impact on prognosis, therapeutic choice, and quality of life.​The manual of 352 pages, enriched by 256 illustrations, almost all in colour, is structured as a collection of clinical oncology cases in which the integration of PET/CT with FDG to the classic diagnostic algorithm has been proposed, including standard radiological and laboratory texts. The volume is divided into 12 sessions, analysing cases concerning gall bladder and bile ducts, head and neck, colon and rectum, oesophagus, gynaecology, lymphomas and thymomas, breast, melanoma, pancreas, lung, stomach and urinary tract. In each session, interesting case reports are structured as individual chapters. The starting point of each case is eepresented by the de- tailed description of the clinical history, including previous diagnostic data and ongoing therapy. Then the role of PET/CT (in staging, restaging, prognostic evaluation, response to therapy) is considered on the basis of its capability to answer the diagnostic question made by the clinician. The answer is widely expressed in a report in which the information obtained is described, individuating areas with FDG uptake and their distribution, with the major goal of defining the metabolic activity of the neoplasm. The report is written as clearly and understandably as possible to serve as the communication tool for the patient and the medical prescriber. Each clinical case, supported by an extensive iconographic collection, ends with conclusions and key points. In most of the pictures, coloured arrows help to correctly indicate to the reader the anatomical area and/or relevant issues. With the same purpose, drawings better explaining some pictures, more difficult to be understood, are also occasionally presented. In conclusion, this book provides to students and experts in nuclear medicine, radiology and oncology, but also to all other clinicians interested in better understanding the clinical role of PET/FDG in oncology, a guidance for the interpretation of the images, which correlate anatomical and functional data. In this way, a clinically valuable report correctly answering the diagnostic query is obtained. This final result may be useful for all physicians who are in charge of oncological patients to contextualize, explain and communicate the results obtained with PET/CT, which may have a dramatic impact on prognosis, choice of treatment and the quality of life not only of the patient but also of their family members

    Parotid function after selective deep lobe parotidectomy

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    Selective deep lobe parotidectomy is a demanding technique, but it preserves healthy glandular tissue, improves cosmetic results and minimises the incidence of Frey’s syndrome. We have evaluated postoperative function of the superficial lobe of the parotid after selective resection of the deep lobe. Fourteen patients who each had a mass involving the deep lobe of the parotid were selected from 127 patients with tumours of the parotid gland who were seen and treated between January 2001 and March 2004. Of the 14, 12 matched the study criteria. The preoperative diagnosis was made using both computed tomography (CT) and ultrasound or fine needle aspiration cytology, and the diagnosis was confirmed by histological analysis. All cases were treated by the same surgeon. At 6 months follow-up all patients had a House–Brackmann test, iodine starch test, and scintigraphy of both parotid glands. After scintigraphy the maximum uptake value and function of the gland were evaluated with the concentration index (CI) and the CI percentage ratio. The concentration function of the gland in the resected side of the study group had a mean (S.D.) CI index of 5.5 (3.6) and a CI percentage ratio of 84%. Selective deep lobe parotidectomy has the following advantages: it minimises the impact of treatment on the facial contour, it does not increase postoperative morbidity and it preserves the function of the glan
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