173,582 research outputs found
Segenhoe Estate, Fernhill, near Dulwich Hill [cartographic material] /
No full textSales plan for Fernhill (now part of Hurlstone Park), New South Wales. Includes local sketch.; Oriented with north to left.; "Torrens Title".; "Terms: 10% deposit. Balance in 36 equal monthly payments with interest at 5% payable quarterly."; "Cowdery & Ewing, licensed surveyors under R.P.A., 88 Pitt St., Sydney".; Also available in an electronic version via the internet at: http://nla.gov.au/nla.map-lfsp1077
St. Aubins Estate, Fernhill, near Dulwich Hill [cartographic material] /
No full textSales plan area bounded by Duntroon and Garnet Streets and Canterbury New Road, Fernhill (now part of Hurlstone Park), New South Wales. Includes local sketch.; "Torrens Title".; "Terms: 10% deposit. Balance in 36 equal monthly payments with interest at 5% payable quarterly."; "Cowdery & Ewing, licensed surveyors under R.P.A., 88 Pitt St., Sydney".; "J.M. Cantle, 90 Pitt St."; Also available in an electronic version via the internet at: http://nla.gov.au/nla.map-lfsp1087
Multiple sclerosis: oligodendrocytes display cell death-related molecules in situ but do not undergo apoptosis
No full textTo investigate whether apoptosis is involved in the fate of oligodendrocytes in chronic multiple sclerosis lesions, the pro-apoptotic molecules fas and tumor necrosis factor receptors and the anti-apoptotic molecule bcl-2 were examined by immunohistochemistry, and DNA fragmentation was assessed by an end labeling technique. Fas and both tumor necrosis factor receptors were preferentially expressed on oligodendrocytes in multiple sclerosis lesions, this phenotype being more evident at the lesion edge. The ligand for fasL, was constitutively present at high levels on microglia. The anti-apoptotic molecule bcl-2 was selectively expressed on oligodendrocytes in silent lesions and on astrocytes in active lesions. These molecules were also detected in control material, albeit at lower levels. In chronic active lesions a few inflammatory cells displayed fas reactivity, whereas the majority expressed bcl-2. DNA fragmentation was found in a number of infiltrating cells and some microglia, whereas, with one possible exception, oligodendrocytes showed no evidence of apoptosis. Thus, while apoptosis is involved in the elimination of infiltrating cells, it plays little or no role in oligodendrocyte depletion in multiple sclerosis, a process that may be related to a lytic pathway. In addition, microglia constitutively displayed the ligand for fas, and appeared to be the major effector cell population in the central nervous system
Activation of NF-kappaB and c-jun transcription factors in multiple sclerosis lesions. Implications for oligodendrocyte pathology
No full textOligodendrocytes are a major target of the purported autoimmune response in multiple sclerosis (MS) lesions, but little is known about the mechanisms underlying their demise. Despite the expression of proapoptotic receptors, these cells are rarely seen to undergo apoptosis in situ. On the other hand, cytotoxic mediators present in MS lesions, such as tumor necrosis factor-α, are known to generate survival signals through the activation of the transcription factors NF-κB and c-jun. The aim of this study was to investigate in chronic active and silent MS lesions and control white matter the expression of c-jun, its activating molecule, JNK, as well as NF-κB complex and its inhibitor, IκB. By immunohistochemistry we found negligible reactivity for these molecules in control white matter and silent MS plaques. In active MS lesions, double-label immunohistochemistry with oligodendrocyte markers showed up-regulation of the nuclear staining for both NF-κB and JNK on a large proportion of oligodendrocytes located at the edge of active lesions and on microglia/macrophages throughout plaques. Oligodendrocytes showed no reactivity for IκB, which was predominantly confined to the cytoplasm of microglia/macrophages. We hypothesize that activation of these transcriptional pathways may be one mechanism accounting for the paucity of oligodendrocyte apoptosis reported in MS
Kathleen Raine: Una poeta de modulaciones, resonancias metafísicas e intimaciones visionarias
No full textResumen:
En el ensayo “John Donne and the Baroque Doubt” (1945) la poeta Kathleen Raine examina la poesía metafísica como reflejo de una transición entre el medioevo y la modernidad. Las reflexiones sobre la poesía metafísica, y lo que Raine describe en ella como un estado de “duda” espiritual, resultan relevantes puesto que la tensión y el equilibrio entre dos cosmovisiones que la autora destaca en Donne no son ajenos a su propia práctica poética. Desde la puesta en relación de poemas y ensayos pertenecientes a distintos momentos del proceso creativo, este artículo intenta señalar las continuidades de una voz en la poesía de Raine que aspira a encarnar la “intuición metafísica” de aunar lo eterno y lo transitorio en un movimiento trascendente de correspondencias visionarias entre el microcosmos y el macrocosmos.
Palabras clave: Kathleen Raine – poesía metafísica- Romanticismo- Blake.
Abstract:
In the essay "John Donne and the Baroque Doubt" (1945), the poet Kathleen Raine examines metaphysical poetry as reflecting the transition from the Middle Ages to Modernity. The condition of spiritual doubt that attracts and repels is relevant as it is also present in Raine's own poetic work. This article examines the progression of a voice that aspires to incarnate the "metaphysical intuition" by taking into account Raine's poems and essays at different stages of creative work. The attempt to unify the eternal and the transient reveals visionary correspondences between the microcosmic and the macrocosmic realms
Members of the Monte Carlo Russian Ballet on tour in New Zealand, 1937 [picture] /
No full textTitle devised by cataloguer based on caption list prepared by researcher.; Photographer's stamp on verso.; Part of the Maroussia Richardson collection.; Also available in electronic version via the Internet at: http://nla.gov.au/nla.ms-ms9915-2-13
Members of the Monte Carlo Russian Ballet company visiting eminent Maori women including Lady Pomare (seated front centre) at Hiwiroa, Lower Hutt, New Zealand, 1937, 2 [picture] /
No full textTitle devised by cataloguer based on caption list prepared by researcher.; Photographer's stamp on verso.; Part of the Maroussia Richardson collection.; Also available in electronic version via the Internet at: http://nla.gov.au/nla.ms-ms9915-2-11
Multiple sclerosis: expression of molecules of the tumor necrosis factor ligand and receptor families in relationship to the demyelinated plaque
No full textAustralia, Barrier Reefs, from Raine Island to Cape York [cartographic material] /
No full textChart of part of Great Barrier Reef, Queensland from Raine Island northwards to Cape York, with relief shown by soundings and hachures. Also shows tracks of Captain Blackwood and Captain King's inner route.; Prime meridian: Greenwich.; "1749"--Bottom right corner below neat line.; "XXVIII"--Bottom right corner below neat line.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.map-vn3791410.Barrier Reefs from Raine Island to Cape Yor
The green turtle, Chelonia Mydas, population of Raine Island and the northern Great Barrier Reef : 1843 -2001
No full textEuropean history of the use of Raine Island and nesting green turtles is reviewed. Results of a diverse mosaic of investigations of the reproductive biology of the nesting population of green turtles using Raine Island and the adjacent islands are presented. These studies have focused on defining the fimdamental characteristics of the breeding population, with more in-depth studies being conducted elsewhere. Studies at Raine Island have defined the species composition, morphology of adults, eggs and hatchlings, hatching and emergence success, sources of mortality of adults, eggs and hatchlings as well as the nesting environment
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