1,721,208 research outputs found
Setting up tissue culture techniques for regeneration of apricot transgenic shoots in a transformation program for resistance to Plum Pox Virus.
No full textApricot is a recalcitrant species for the regeneration necessry for its genetic transformation
5HT2A polymorphism His452Tyr in a German Caucasian systemic sclerosis population : authors' response
No full textHLA DR2 PHENOTYPE IN INSULIN-DEPENDENT DIABETICS - ITS ROLE ON DEVELOPMENT OF REMISSION PHASES AND DEGENERATIVE COMPLICATIONS OF DIABETES
No full textThe role of genetics in the susceptibility to type I (insulin-dependent) diabetes (IDDM) has been clarified in recent years by family and population studies, showing that a major role is played by the HLA region. Alleles B8, B15, and B18 were first recognized as more frequent in type I dabetic patients, but further studies showed that their enhanced frequencies were secondary to the increase in DR3 and DR4 frequencies. On the contrary, HLA DR2 antigen has been found to be very rare in IDDM patients; so far it has been considered to be protective against the development of diabetes. Clinical, immunologic, and metabolic studies have evidenced the existence of further heterogeneity among IDDM patients. The aim of the study was to investigate the association between HLA factors and other clinical features (remission phase, age at the onset, familiarity, and complications) in a sample of Italian diabetic patients
Hyperplasia of Suprarenal Medulla
No full textA case of arterial hypertension due to suprarenal medulla hyperplasia is reported. Having accepted the existence of this form, the problem of its recognition is stressed, in the presence of catecholamine pathology, even though the type or site of its anatomo-pathological substrate cannot be identified, explorative surgery and possible removal of the suprarenal glands can be indicated
Genetic interactions of pillar (columnar), compact, and dwarf peach tree genotypes
No full textA study was conducted to determine genetic control of the columnar or pillar (PI) growth habit, and to evaluate
the effects of interactions of various genes that influence peach [Prunus persica (L.) Batsch (Peach Group)] growth habit.
The PI habit (brbr) examined in this study was inherited as a monogenic trait expressing incomplete dominance. The
heterozygous Brbr derived from crosses between standard (ST) and PI genotypes wasrecognized as an upright (UP) tree
with narrower branch angles than ST trees but wider than PI trees. The combination of brbr and brachytic dwarf (DW)
(dwdw) produced dwarf-pillar (DWPI) trees. The effects of the heterozygous Brbr in combination with dw and/or compact
(CT) (Ct) could not be recognized by visual observation. Compact pillar (CTPI) trees resulted from the expression of Ct_
brbr. These trees were distinguished from globe-shaped (GL) trees (Ct_Brbr) by the more upright growth habit of the
CTPI trees. This genetic study highlights the genetic “plasticity” of tree growth habit in peach. The investigation of novel
growth habits extends our concept of the peach tree. Some growth habits such as PI may have commercial potential for
high-density peach production systems. Others, such as PIDW and CTPI may have potential as ornamentals
Assessment of vascular involvement
No full textOur objective was to identify a core set of variables for the assessment of vascular involvement in scleroderma that is simple, reproducible, and reflects the presence of vascular disease in SSc. To do so we carried out an extensive literature review of published studies relating to the assessment of vascular involvement in SSc, i.e. studies dealing with clinical parameters, functional vascular studies, cold presser testing, nailfold capillary microscopy and circulating vascular markers. After extensive review of published studies and critical assessment of proposed vascular parameters, the subcommittee endorsed what it considers to be the minimal requirements for the documentation of vascular involvement in SSc. The core set variables include two parameters: Raynaud's phenomenon and digital ulcers. This set is simple, reproducible and should be included in the assessment of SSc patients in clinical investigational studies. The subcommittee also however recognizes that there exists a promising set of vascular variable that still needs further investigation
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