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Progressive deactivation of 5-HT receptors on mononuclear cells during migraine crisis
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Impairment of 5-HT binding to lymphocytes and monocytes from tension-type headache patients
No full textAnalysis of phenotypic and functional abnormalities observed in cell immune system of juvenile cluster headache patients
No full textELEVATED FREQUENCY OF HLA SHARED-HAPLOTYPES IN MIGRAINE FAMILIES
No full textAssociations between HLA antigens and disease susceptibility have been investigated in several pathological conditions. Previous studies in selected migraine populations did not reveal any association with the HLA system. It is widely accepted that migraine is a disease with familial incidence. The genetic basis of migraine occurrence within 8 families with more than one member affected in two generations was studied. 60 individuals were studied; 33 of them were affected by migraine. HLA-A,B,C,DR typing was performed in 41 individuals using the microlymphocytotoxicity technique of Terasaki. The studied pedigrees failed to identify a particular HLA antigen or HLA haplotype as a genetic marker of migraine. Among the total number of HLA typed individuals entering the study, Sib-pair analysis was done in 20 pairs. The observed frequency of shared-haplotypes differed from the expected frequency: 60% of compared pairs shared one haplotype (expected frequency 50%) and 30% shared two haplotypes (expected frequency 25%)
Disabilità lavorativa nell’emicrania. Studio psicometrico mediante questionari CBA e MGMP
No full textChanges of 5HT binding to mononuclear cells in migraine adolescents are dependent to HLA aplotypes expression
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