7,715 research outputs found
L'art roman en France, présenté par M. Aubert avec la collaboration de G. Gaillard, M. de Bouard, R. Crozet, M. Durliat, M. Thibout, J. Vallery-Radot, F. Benoit.
No full textMussat A. L'art roman en France, présenté par M. Aubert avec la collaboration de G. Gaillard, M. de Bouard, R. Crozet, M. Durliat, M. Thibout, J. Vallery-Radot, F. Benoit.. In: Annales de Bretagne. Tome 69, numéro 1, 1962. pp. 179-180
Le tombe medioassire dell’Area G: alcune riflessioni
No full textAll’interno del grande edificio di epoca medioassira messo in luce nell’Area G, A-D 7-10, in quella che doveva essere l’area della residenza privata, il bitanu, nel corso della campagna di scavo del 2003 sono state trovate tre tombe grosso modo contemporanee, che hanno restituito ricche collezioni di oggetti, alcuni dei quali di particolare pregio fornendo importanti indizi sui costumi funerari della Giazira della fine del II millennio
Cryptolarynx undefined-6 Haran, Marvaldi, Benoit, Oberlander, Stals & Oberprieler, 2023, sp. nov.
No full textCryptolarynx sp. 6 (near C. hirtulus sp. nov.) REPUBLIC OF SOUTH AFRICA – Northern Cape • 1 ♂, 1 ♀; Calvinia N, Hantamsberg; 31.352° S, 19.803 °E; elevation 1544 m; 9 Nov. 2018; R. Borovec leg.; FFWS.Published as part of Haran, Julien M., Marvaldi, Adriana E., Benoit, Laure, Oberlander, Kenneth, Stals, Riaan & Oberprieler, Rolf G., 2023, Revision of the enigmatic South African Cryptolaryngini (Coleoptera, Curculionidae), with description of a new genus and twenty-two new species, pp. 1-89 in European Journal of Taxonomy 877 (1) on page 66, DOI: 10.5852/ejt.2023.877.2151, http://zenodo.org/record/811058
Il Chronicon di Santa Maria del Principio (1313 circa) e la messa in scena della liturgia nel cuore della Cattedrale di Napoli
No full textNell'articolo si analizza un testo liturgico, mai analizzato nel suo complesso, tramandato da un unico codice conservatosi nell'Archivio diocesano di Napoli. Il testo si analizza al fine di dedurne informazioni utili alla ricostruzione della facies architettonica della cattedrale di Napoli nel Medioevo
Storie di obelischi egizi nei giardini romani tra Cinque e Seicento
No full textSi presentano i contesti degli obelischi nelle ville di Roma, con una nuova proposta interpretativa per l'obelisco di Villa Borghes
Visages du Dauphiné et de la Provence : Veyret (P.), Avezou (R.), Fernandat (R.), Vaillant (P.), et Gaillard (G.). Visages du Dauphiné ; Bénévent (E.), Léonard (E.-G.), Benoit (F.), Girard (J.), et Durand (B). Visages de la Provence. Paris, Éditions des Horizons de France (collection Provinciales) 1950
No full textGodechot Jacques. Visages du Dauphiné et de la Provence : Veyret (P.), Avezou (R.), Fernandat (R.), Vaillant (P.), et Gaillard (G.). Visages du Dauphiné ; Bénévent (E.), Léonard (E.-G.), Benoit (F.), Girard (J.), et Durand (B). Visages de la Provence. Paris, Éditions des Horizons de France (collection Provinciales) 1950. In: Annales du Midi : revue archéologique, historique et philologique de la France méridionale, Tome 62, N°10, 1950. pp. 192-194
Crematogaster cerasi Wheeler, G. C. & Wheeler, J. 1973
No full textCrematogaster cerasi Wheeler, G.C. & Wheeler, J. 1973 Distribution in North Carolina: All regions. Counties: CH, CK, CO, JH, OR, WK, WT (material examined) and BN, CA, CT, HE, HW, JA, MA, TR (in literature). Distribution in surrounding states: GA (Johnson 1988, Ipser et al. 2004), SC (Johnson 1988), TN (Dennis 1938) and VA (Kjar 2009).Published as part of Guénard, Benoit, Mccaffrey, Katherine A., Lucky, Andrea & Dunn, Rob R., 2012, Ants of North Carolina: an updated list (Hymenoptera: Formicidae), pp. 1-36 in Zootaxa 3552 on page 2
Maternal representations and infant attachment: An examination of the prototype hypothesis
No full textThe prototype hypothesis suggests that attachment representations derived in infancy continue to influence subsequent relationships over the life span, including those formed with one's own children. In the current study, we test the prototype hypothesis by exploring (a) whether child-specific representations following actual experience in interaction with a specific child impacts caregiver-child attachment over and above the prenatal forecast of that representation and (b) whether maternal attachment representations exert their influence on infant attachment via the more child-specific representation of that relationship. In a longitudinal study of 84 mother-infant dyads, mothers' representations of their attachment history were obtained prenatally with the Adult Attachment Interview (AAI; M. Main, R. Goldwyn, & E. Hesse, 2002), representations of relationship with a specific child were assessed with the Working Model of the Child Interview (WMCI; C.H. Zeanah, D. Benoit, & L. Barton, 1986), collected both prenatally and again at infant age 11 months, and infant attachment was assessed in the Strange Situation Procedure (M.D.S. Ainsworth, M.C. Blehar, E. Walters, & S. Wall, 1978) when infants were 11 months of age. Consistent with the prototype hypothesis, considerable correspondence was found between mothers' AAI and WMCI classifications. A mediation analysis showed that WMCI fully accounted for the association between AAI and infant attachment. Postnatal WMCI measured at 11 months' postpartum did not add to the prediction of infant attachment, over and above that explained by the prenatal WMCI. Implications for these findings are discussed.No Full Tex
Structure and Stability of Human Telomeric G-Quadruplex with Preclinical 9-Amino Acridines
No full textG-quadruplexes are higher-order DNA structures formed from guanine-rich sequences, and have been identified as attractive anticancer drug targets. Elucidating the three-dimensional structure of G-quadruplex with 9-amino acridines and the specific interactions involved in binding selectivity are the key to understanding their mechanism of action. Fluorescence titration assays, competitive dialysis and NMR studies have been used to study the binding specificity of 9-amino acridines to DNA. Structural models of the complexes with the telomeric DNA G-quadruplex based on NMR measurements were developed and further examined by molecular dynamics simulations and free energy calculations. Selective binding of 9-amino acridines for G-quadruplex sequences were observed. These compounds bind between A and G-tetrads, involving significant π-π interactions and several strong hydrogen bonds. The specific interactions between different moieties of the 9-amino acridines to the DNA were examined and shown to play a significant role in governing the overall stabilities of DNA G-quadruplex complexes. Both 9-amino acridines, with similar binding affinities to the G-quadruplex, were shown to induce different level of structural stabilization through intercalation. This unique property of altering structural stability is likely a contributing factor for affecting telomerase function and, subsequently, the observed differences in the anticancer activities between the two 9-amino acridines.This work was partially supported by grants from Spanish Ministerio de Ciencia e Innovacio´n MICINN (CTQ2008-00177, CTQ2010-20541), Generalitat de
Catalunya, (2009/SGR/208), the EU COST action (MP0802), the University of Milano (PUR09) and by MIUR (Funds PRIN09).The funders had no role in study design,
data collection and analysis, decision to publish, or preparation of the manuscript.Peer reviewe
Cellular imbalance of specific RNA-binding proteins associates with harmful R-loops
No full textUnderstanding how the assembly of nascent mRNA into a ribonucleoprotein (mRNP) influences R-loop homeostasis is crucial for gaining insight into the cellular mechanisms that prevent genome instability. Here, we identify three RNA-binding proteins, Rie1, Rim4 and She2, whose expression levels are important to limit R-loop accumulation and, thus, to prevent DNA damage. Interestingly, Rim4 and She2 are overrepresented in CBP80-containing mRNPs formed in the absence of THO. In addition, we found that an excess of the RNA exosome component Dis3 impairs its function, promoting R-loops, particularly from non-coding RNAs, which cause genomic instability. Our results indicate that changes in the availability of different RBPs or RNAs, causes R-loop-mediated DNA damage in the cell. These results may help to understand the mechanism that promotes cancer, as several RBPs are overexpressed in different types of tumors.Research was funded by the following grants: PID2019-104270GB-I00 funded by Ministerio de Ciencia e Innovación/Agencia Estatal de Investigación/10.13039/501100011033 and FIUS22/0178 from Fundación de Investigación de la Universidad de Sevilla to AA; P18-FR-655 funded by Consejería de Universidad, Investigación de la Junta de Andalucía and by the European Union to AA and AGR; PP2024/00000588 funded by the University of Seville to AGR; ANR-21-CE12-0040 funded by Agence Nationale pour la Recherche to BP and PJA2022070005310 funded by Fondation ARC pour la recherche contre le Cancer to BP. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer reviewe
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