16,786 research outputs found
Telegram from Irving Flicker, with response from Eliahu Epstein, regarding the Israeli Government
No full textJersey Homesteads (later the Borough of Roosevelt) was established in the 1930s as an agro-industrial cooperative community. It was established specifically for urban, Jewish garment workers, many of whom had emigrated from Europe. Mayor Irving Flicker sent a telegram to the Jewish Agency for Palenstine, to congratulate the Israeli government on its recent independence, and on the recognition by the United States of Israel as an independent country. Eliahu Epstein, Representative of the Provincial Government of Israel, sent a reply telegram to Flicker, thanking him for his message and sending his regards to the Roosevelt Community. As a predominantly Jewish community, the establishment of Israel as an independent state was a significant event that connected Jersey Homestead citizens to the global Jewish community
[Letter from Albert K. Epstein to R. K. Brodice - December 5, 1940]
No full textLetter from Albert K. Epstein to Mr. R. K. Brodice informing him of the events that occurred at the olemargarine industry hearing on emargol, mono- and di-glycerides. He mentions how some members of the industry attempted to use the word "glycerinated fat" when defining oleomargarine and how there was some confusion as to the correct proportions for monoglycerides and diglycerides in oleomargarine products and some suspicion as to the true content of them
[Letters from Benjamin R. Harris and Albert K. Epstein to Dr. Meyer Bodansky - September 1940]
No full textLetters from Albert K. Epstein and Benjamin R. Harris to Dr. Bodansky discussing possible feeding tests on the "solvit" substance and the "emargol" substance of The Emulsol Corporation
Carving a legacy : the identity of Jacob Epstein (1880-1959)
No full textThe purpose of this thesis is to examine the efforts which were made during the life of Jacob Epstein and at the time his death to fix a particular identity that has thus shaped his legacy. The question that this thesis wishes to address is: how was Jacob Epstein's legacy carved?
The first part of this thesis, entitled 'Remembering Epstein', seeks to unpack and examine the written discourse surrounding his death. This will be done by assessing the themes, debates and considerations of Epstein's position in the history of art and will focus on four case studies: the obituaries and memorial pieces that were written immediately after Epstein's death; a memorial service that was held at St. Paul's Cathedral; a failed proposal
to tum Epstein's home studio into a museum; and the organisation and critical reception of the Epstein Memorial Exhibition held in Edinburgh in 1961. The second part of this thesis, entitled 'Writing a Legacy', attends to the analysis of texts which were written about or by Epstein throughout his career. This will be done through a close examination of those texts which have come to shape our understanding of Epstein's place in the history of art and will focus on five case studies: the writings of T. E. Hulme; Epstein by Bernard Van Dieren; a series of interviews with Epstein by Arnold Haskell, entitled The Sculptor Speaks; Epstein's role in protesting against repairs to ancient sculpture in the British Museum; and a chapter entitled 'My Place in Sculpture' from the 1954 edition of Epstein's autobiography. The final part of the thesis, entitled 'Selected Works', will focus on six separate sculptures as case studies for assessing different aspects of Epstein's artistic output. The works which
will be examined: The Rock Drill (1913), The Risen Christ (1917-19), Madonna and Child (1926-27), Genesis (1929), Albert Einstein (1933), and Madonna and Child (1950-52)
Clonal origin of Epstein-Barr virus-infected T/NK-cell subpopulations in chronic active Epstein-Barr virus infection
No full textClonal expansion of Epstein-Barr virus (EBV) infected B-cells occasionally occurs in immunocompromized subjects. EBV-infected T/natural killer (NK)-cells proliferate in patients with chronic active EBV infection (CAEBV) that is a rare mononucleosis syndrome. It is classified into either T-cell type or NK-cell type according to the primary target of infection, while the pathogenesis remains unclear. To search the clonal origin of EBV-infected T/NK-cells, virus distribution and clonotype were assessed by using highly purified cell fractions obtained from 6 patients. Patient 1 had a monoclonal proliferation of EBV-infected T-cell receptor Vδ2/Vγ9-expressing cells, and carried lower copy number of EBV in αβT-cells. Patients 2 and 3 had a clonal expansion of EBV-infected CD4+T-cells, and lower EBV load in CD56+cells. Patients 4, 5 and 6 had an expansion of CD56+cells with higher EBV load than CD3+cells. EBV-terminal repeats were determined as clonal bands in the minor targeted populations of 5 patients. The size of terminal repeats indicated the same clonotype in minor subsets as in major subsets of 4 patients. However, EBV was not detected in bone marrow-derived lineage negative CD34+cells of patients. These results suggested that EBV could infect T/NK-cells at differentiation stage, but spared bone marrow CD34+hematopoietic stem cells in CAEBV patients
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Does Texas Value Reliable Energy? Texas Energy Policy with Alex Epstein
No full textAlex Epstein, author of "The Moral Case for Fossil Fuels," discusses reliable energy and Texas' energy policy with Salem Center's Gregory Salmieri and Carlos Carvalho.Salem Cente
The immunology of Epstein-Barr virus infection
No full textEpstein-Barr virus is a classic example of a persistent human virus that has caught the imagination of immunologists, virologists and oncologists because of the juxtaposition of a number of important properties. First, the ability of the virus to immortalize B lymphocytes in vitro has provided an antigen presenting cell in which all the latent antigens: of the virus are displayed and are available for systematic study. Second, the virus presents an ideal system for studying the immune parameters that maintain latency and the consequences of disturbing this cell-virus relationship. Third, this wealth of immunological background has provided a platform for elucidating the role of the immune system in protection from viral-associated malignancies of B cell and epithelial cell origin. Finally attention is now being directed towards the development of vaccine formulations which might have broad application in the control of human malignancies
[Letter from Albert K. Epstein to Dr. Meyer Bodansky - November 20, 1930]
No full textLetter from Albert K. Epstein to Dr. Meyer Bodansky suggesting that he read a critique an author wrote on his textbook
Interview with Paul S. Epstein
No full textMemoirs recorded by Paul Sophus Epstein (1883-1966) with his wife, Alice Epstein, late in 1965 and possibly into early 1966. He describes his undergraduate and graduate study in physics at Moscow University, 1901-1909, under P. N. Lebedev, and his move to Munich in early 1910 to begin his doctoral study under A. Sommerfeld. He remembers his professors in Russia: N. V. Bugaev, N. A. Umov, B. Mlodziowski, N. E. Zhukovsky, A. P. Sokolov; his Russian student colleagues T. P. Kravets, A. K. Timiryazev, P. P. Lazarev, and V. K. Arkadiev. He acknowledges P. Ehrenfest's influence in the move to Munich and the change from experimental to theoretical physics, and he recounts aspects of Ehrenfest's early career. Educational practices and social conditions of the turn of the century and early decades of the twentieth century in both Russia and Germany are discussed in detail, including the situation of European Jews and anti-Semitic laws and attitudes. Sommerfeld's scientific background and connections in Königsberg, Göttingen and Aachen are described: mathematicians D. Hilbert, F. Klein, H. Minkowski; the philosopher E. Husserl. Epstein remembers his German professors: C. L. F. Lindemann (mathematics), P. H. von Groth (crystallography), W. C. Röntgen (physics); his Munich student colleagues P. Debye, M. von Laue, A. F. Ioffe, P. P. Koch, P. P. Ewald, and A. Rosenthal; and he recollects important intellectual exchanges at Munich Stammtische. Epstein notes his involvement with avant-garde Munich artists from the Blaue Reiter circle, including P. Klee, W. Kandinsky, F. Marc, and A. von Jawlensky. World War I delays the completion of his studies and creates financial hardship. He recounts leaving Munich for Zurich (1919), where he meets A. Einstein; his Habilitation thesis on the application of the Stark effect to optics creates a stir. He subsequently moves to Leiden to assist Ehrenfest and H. Lorentz (1921). During these years, Epstein marries and divorces Mina (Maria) and develops interest in psychoanalysis; he meets Freud in Switzerland ca. 1920. Epstein meets R. A. Millikan in Leiden, decides to take teaching position at California Institute of Technology in Pasadena. He describes his early period at Caltech and colleagues there (1920s). Epstein ends with an account of Röntgen's career, especially his discovery of X rays; discusses Röntgen's relations with Sommerfeld in Munich
Epstein-Barr Virus LF2: an Antagonist to Type 1 Interferon
No full textAbstractUpon viral infection, the major defense mounted by the host immune system is activation of the interferon (IFN)-mediated antiviral pathway, which is mediated by IFN regulatory factors (IRFs). In order to complete their life cycle, viruses must modulate host IFN-mediated immune responses. Despite its association with significant human health problems, activities of Epstein-Barr virus (EBV), a human tumor-inducing herpesvirus, to evade host IFN-mediated innate immunity have not been well characterized. To search for EBV genes that block IFN signal transduction, we carried out a screening of EBV open reading frames for their abilities to block IFN-alpha/beta-mediated luciferase expression upon Sendai virus infection. This screening demonstrates that EBV LF2 tegument protein specifically interacts with the central inhibitory association domain of IRF7, and this interaction leads to inhibition of the dimerization of IRF7, which suppresses IFN-alpha production and IFN-mediated immunity. This demonstrates a novel immune evasion mechanism of EBV LF2 in blocking cellular IRF7-mediated innate immunity.<br/
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