2,649 research outputs found
Structure, soil-structure response and effects of damage based on observations of horizontal-to-vertical spectral ratios of microtremors
No full textThe microtremor horizontal-to-vertical-spectral-ratio (HVSR) technique is widely used in the urban environment to assess the
fundamental frequency response of the ground. Extensive literature exists about case histories using HVSR for microzonation in several
cities, but no systematic studies have been devoted to check the presence of soil–structure interaction effects, and even less attention to study building behaviour after earthquake damage. To evaluate the above-mentioned effects, a series of experiments are reported in this article.
We first made a series of microtremor measurements on buildings and civil structures to evaluate the reliability of fundamental frequency
determinations. Then, we considered several case studies to evaluate the effect of soil–structure interaction in estimates of site response in
the presence of tall buildings. Finally, an experiment on the frequency change due to damage was performed. It was possible to confirm that HVSR is able to detect building fundamental modes and once known the building frequency, it is also possible to detect the presence of
soil–structure interaction. Thus, once the presence of the building natural frequency is identified, it is possible to infer the site response from free field measurements. We also found that the HVSR technique is equally useful for detecting structural damage by determining the frequency shift of the buildings
Kisspeptin receptor on the sperm surface reflects epididymal maturation in the dog
No full textAlongside the well-known central modulatory role, the Kisspeptin system, comprising Kiss1, its cleavage products (Kisspeptins), and Kisspeptin receptor (Kiss1R), was found to regulate gonadal functions in vertebrates; however, its functional role in the male gamete and its localization during maturation have been poorly understood. The present study analyzed Kisspeptin system in dog testis and spermatozoa recovered from different segments of the epididymis, with focus on Kiss1R on sperm surface alongside the maturation during epididymal transit, demonstrated by modification in sperm kinetic, morphology, and protamination. The proteins Kiss1 and Kiss1R were detected in dog testis. The receptor Kiss1R only was detected in total protein extracts from epididymis spermatozoa, whereas dot blot revealed Kiss1 immunoreactivity in the epidydimal fluid. An increase of the Kiss1R protein on sperm surface along the length of the epididymis, with spermatozoa in the tail showing plasma membrane integrity and Kiss1R protein (p < 0.05 vs. epididymis head and body) was observed by flow cytometry and further confirmed by epifluorescence microscopy and Western blot carried on sperm membrane preparations. In parallel, during the transit in the epididymis spermatozoa significantly modified their ability to move and the pattern of motility; a progressive increase in protaminization also occurred. In conclusion, Kisspeptin system was detected in dog testis and spermatozoa. Kiss1R trafficking toward plasma membrane along the length of the epididymis and Kiss1 in epididymal fluid suggested a new functional role of the Kisspeptin system in sperm maturation and storage
Identification of the intermediate hosts of Habronema microstoma and Habronema muscae under field conditions.
No full textInfluência dos ácidos graxos na dieta sobre a cinética espermática de búfalos no CASA.
No full textA análise seminal computadorizada (CASA) é ferramenta importante para fornecer, dentre vários dados, o parâmetro cinético dos espermatozoides (CONTRI, 2010)
Pulse wave Doppler ultrasound of testicular arteries and their relationship with semen characteristics in healthy bulls
No full textBackground: Semen evaluation is used to estimate the testicular function. In bulls, the spermatozoa present in the ejaculate are the result of a process that begun more than 2 mo earlier, bequeathing a delayed depiction of the actual function of the testis. Since testis vascularization might be critical for the gonad function, selected pulse wave Doppler ultrasound parameters were assessed in this study, for instance the peak systolic velocity, the end diastolic velocity and the resistive index of the testicular artery along the spermatic cord, the marginal portion of the testicular artery and the intratesticular branches of the testicular artery both in healthy adult and young bulls. Correlations between these parameters and characteristics of semen that was collected numerous times, before and after the Doppler ultrasound examination. Results: The peak systolic velocity and the end diastolic velocity measured in the testicular artery along the spermatic cord (supratesticular artery - SA) were variable among the bulls and within individual bulls, likely due to the convoluted course of the vessel. The resistive index was found highly repeatable in the same bull. A reduction in the resistive index was found between the supratesticular artery and the marginal portion of the testicular artery (P < 0.01), and between the marginal portion of the testicular artery and the intratesticular branches of the testicular artery (P < 0.05). No differences were recorded for the pulse wave Doppler ultrasound parameters in young bulls compared with adults. A significant correlation was found between the resistive index of the marginal portion of the testicular artery and total sperm in the ejaculate (r = 0.516, P < 0.05), the immature sperm (r = 0.462, P < 0.05), the teratoid sperm (r = 0.375, P < 0.05), and the "Dag defect" sperm (r = 0.389, P < 0.05). Similarly, the resistive index of the intratesticular branches of the testicular artery were found correlated with the total sperm number in the ejaculate (r = 0.568, P < 0.05), the immature sperm (r = 0.523, P < 0.05), the teratoid sperm (r = 0.418, P < 0.05), and the "Dag defect" sperm (r = 0.341, P < 0.05). Conclusions: The data presented in this study suggest that the resistive index, measured at the marginal portion of the testicular artery, could be an easy-to-perform parameter to evaluate the spermatogenesis quality in young bulls and normal adults
Metric-Affine Vector-Tensor correspondence and implications in F(R, T, Q, T, D) gravity
No full textWe extend the results of antecedent literature on quadratic Metric-Affine Gravity by studying a new quadratic gravity action in vacuum which, besides the usual (non-Riemannian) Einstein-Hilbert contri-bution, involves all the parity even quadratic terms in torsion and non-metricity plus a Lagrangian that is quadratic in the field-strengths of the torsion and non-metricity vector traces. The theory results to be equivalent, on-shell, to a Vector-Tensor theory. We also discuss the sub-cases in which the contribution to the Lagrangian quadratic in the field-strengths of the torsion and non-metricity vectors just exhibits one of the aforementioned quadratic terms. We then report on cosmological aspects of the general quadratic theory in the presence of a perfect cosmological hyperfluid and on implications of our findings in the context of F(R, T, Q, T, D) gravity.(c) 2022 Elsevier B.V. All rights reserved
Strain and Shear-Wave Elastography and Their Relationship to Histopathological Features of Canine Mammary Nodular Lesions
No full textMammary gland tumours have a significant impact on the health of dogs, requiring diagnostic tools to support clinicians to develop appropriate therapeutic strategies. Sonoelastography is an emerging technology that is able to define the stiffness of the tissue and has promising applications in the evaluation of mammary gland lesions. In the present study, strain elastography (STE) and shear-wave (SWE) elastography were compared in 38 mammary nodular lesions for their ability to define the histopathological features of canine mammary lesions. Among the techniques, SWE showed better repeatability (intraclass correlation coefficient: 0.876), whereas STE was found to be only acceptable (intraclass correlation coefficient: 0.456). Mammary nodular lesions showed a wide range of tissue stiffening with a similar mean value for STE and SWE in benign (4 ± 0.3 and 115.4 ± 12.6 kPa, respectively) and malignant lesions (3.8 ± 0.1 and 115.5 ± 4.5 kPa, respectively). A significant correlation was found between lesion fibrosis and STE (STE-I: r = 0.513, p < 0.001; STE-R: r = 0.591, p < 0.001) or SWE-S (r = 0.769; p < 0.001). In conclusion, SWE was reliable and correlated with fibrosis and was similar for both benign and malignant lesions, suggesting that other collateral diagnostic techniques should be considered in conjunction with SWE to characterize mammary nodular lesions in dogs
Myocyte survival in the presence of calcium-overload is improved by calcium buffering of the stress-protein GRP94.
No full textFamilial Ehlers‐Danlos Syndrome Type II: Abnormal Fibrillogenesis of Dermal Collagen
No full textAbstract: We examined a father and son affected by Ehlers‐Danlos syndrome type II. Both patients had micrognathia together with ligament and skin hy‐perlaxity. The son exhibited complete cleft palate. Ultrastructural studies revealed abnormal collagen fibrils in the dermis of both patients. In the child the most striking alterations consisted of lateral fusion of an enormous number of collagen fibrils giving rise to huge polymorphic collagen masses. In the father's dermis the great majority of collagen fibrils appesired normal; however, lateral fusion of fibrils together with local abnormal collagen aggregation were occasionally seen. In both patients the dermal elastic network was well developed and elastic fibers appeared normal. Copyright © 1987, Wiley Blackwell. All rights reserve
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