1,720,998 research outputs found
Elderly people and epilepsy : cognitive function
No full textPURPOSE: To evaluate cognitive function in a group of elderly patients with focal epilepsy versus healthy controls. METHODS: A neuropsychological battery assessing major cognitive domains was administered to 40 patients with focal epilepsy aged > or = 60 years, and to 40 controls matched for sex, age, and education. RESULTS: Epilepsy patients performed significantly worse in most of the administered tests than controls (p < 0.05). Poor cognitive performances correlated with use of polytherapy. CONCLUSIONS: Given the high prevalence of epilepsy in the elderly, our results could have important implications for clinical and research purpose
A proposito di due sorelle con Epilessia Parziale Idiopatica (EPI) = Regarding two sisters affected by Idiopathic Partial Epilepsy
No full textTwo sisters, 21 and 11 years old, are affected with Idiopathic Partial Epilepsy. Both of them present a normal neurological examination, absence of intellectual deficit and cerebral lesions documented neuroradiologically. They have a family history of idiopathic partial epilepsy. In both coexist clinical and electroencephalographic manifestations characteristic of Benign partial epilepsy with centro-temporal spikes (BETCS) and/or Idiopathic occipital lobe epilepsies. In particoular: the youngest sister begin, at the age of 4, with a typical picture of Idiopathic occipital lobe epilepsy (early onset) and then, around the age of 8, develops into BECTS. The oldest sister begin, at the age of 7, with typical seizures of BECTS. Around the age of 11, she presents seizures with visual ictal symptoms (phosphenes) and headache, sometimes triggered by photic stimuli (TV), The EEG shows a photosensitivity, seldom with concomitant clinical manifestations. This characteristics remind on the one hand to the Idiopathic occipital lobe epilpsy (late onset), on the other to the Benign photosensitive occipital lobe epilepsy. The two reported cases could support the hypotesis of common genetic factors, with different expressivity, in the different forms of Idiopathic partial epilepsies
Levetiracetam (LEV): prime esperienze di utilizzo nella pratica clinica = Levetiracetam: Initial experience of use in clinical practice
No full textWe studied 61 patients with Epilepsy who have been treated with LEV. Our study suggests that LEV is effective (10% seizure free pts in the drug resistant partial E group, 18% with a reduction ≥ 75% in the same group) and safe. Side effects we rare and in one case only prompted a withdrawal of LEV
Crisi riflesse da scrittura in 2 sorelle con epilessia mioclonica giovanile = Writing reflex seizure in two sibling with juvenile myoclonic epilepsy
No full textWe report on two siblings with juvenile myoclonic epilepsy, in whom jerks of right arm and hand were triggered by writing. On video-EEG monitoring, we illustrated that reflex epileptic myoclonus was more easily triggered by writing that required a higher degree of concentration. These results further support the notion that "praxis-induced" reflex epilepsy occurs in the context of idiopathic generalized epilepsy. Our results also illustrate that writing tasks are more effective in eliciting seizures, when they require higher levels of concentration and mental elaboration
Reflex writing seizures in two siblings with juvenile myoclonic epilepsy
No full textWe report on two siblings who presented with juvenile myoclonic epilepsy, and in whom myoclonic jerks of the right arm and hand were also triggered by writing tasks. Both patients underwent intensive video-electroencephalography monitoring, with simultaneous neuropsychological tests. In both patients, reflex epileptic myoclonus was more easily triggered by writing that required a higher degree of concentration. Conversely, other cognitive tasks, such as reading, typing, thinking, or calculation never elicited any seizures or myoclonus. Valproate was effective in controlling both spontaneous and reflex epileptic seizures. The results of this study further support the notion that 'praxis-induced' reflex epilepsy precipitated by specific stimuli occurs in the context of idiopathic generalized epilepsy. Our results also illustrate that writing tasks are more effective in eliciting seizures when they require higher levels of concentration and mental elaboratio
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