283,415 research outputs found
A good stroke, [R. C. Bourne] [picture] /
No full textInscriptions: Signed "Ape Junior"--Lower right; "A good stroke"--Below image centre; "(R. C. Bourne)"--Below image right; "Vincent Brooks, Day & Son Ltd lith."--Below image left; "Vanity Fair supplement"--Above image.; Caricature of R.C. Bourne by "Ape Junior", originally published in "Vanity Fair, 23 March, 1911".; Condition: Tears at right and lower edges.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-vn3585481.Vanity fair (London, England : 1868
Retelling racialized violence, remaking white innocence: the politics of interlocking oppressions in transgender day of remembrance
Get PDFTransgender Day of Remembrance has become a significant political event among those resisting violence against gender-variant persons. Commemorated in more than 250 locations worldwide, this day honors individuals who were killed due to anti-transgender hatred or prejudice. However, by focusing on transphobia as the definitive cause of violence, this ritual potentially obscures the ways in which hierarchies of race, class, and sexuality constitute such acts. Taking the Transgender Day of Remembrance/Remembering Our Dead project as a case study for considering the politics of memorialization, as well as tracing the narrative history of the Fred F. C. Martinez murder case in Colorado, the author argues that deracialized accounts of violence produce seemingly innocent White witnesses who can consume these spectacles of domination without confronting their own complicity in such acts. The author suggests that remembrance practices require critical rethinking if we are to confront violence in more effective ways. Description from publisher's site: http://caliber.ucpress.net/doi/abs/10.1525/srsp.2008.5.1.2
Being a refugee university student: a collaborative auto-ethnography
No full textIn this paper, we adopt a collaborative autoethnographic approach to explore the experiences of one refugee university student. Our method involved all three authors systematically analysing narratives written by one of us, R Student. These accounts provide deep descriptions of his life while studying at three different UK universities and our analysis of them demonstrates that higher education was a double-edged sword for R student. Our research illuminates how R Student’s past as a survivor of genocide and forced migration; his corrosive and supportive relationships; and neo-liberal policies and practices; all intersected in complex ways to circumscribe his agency and inform his experience as a refugee student. This understanding runs counter to neo-liberal policies and practices within higher education which often blame individuals for the problems they encounter and obscure social and relational forces. In describing the operable effects of abstract policies and concepts upon R Student, our study provides a counter-narrative to neo-liberal discourse and identifies systemic issues that may affect other students too
Samuele R. Bacchiocchi and Family
No full textSeventh-day Adventist author and theologian, Samuele R. Bacchiocchi and his wife and their children at a graduation ceremony at Pontifical University
The association of the paraoxonase (PON1) Q192R polymorphism with depression in older women: findings from the British women's heart and health study
No full textBackground: The association between the R allele of PON1 Q192R and symptoms reported by sheep dippers and Gulf War veterans has been used to suggest a biological basis for these symptoms. In the absence of such studies in non-occupational populations, these conclusions may not be valid.Objective: To examine the association of paraoxonase (PON1) Q192R with a report of ever being diagnosed with depression among a random sample of 3266 British women, aged 60–79 years.Results: The R allele of PON1 Q192R was associated with depression: per-allele odds ratio 1.22 (95% confidence interval: 1.05 to 1.41) in this population.Conclusions: These findings suggest that the association of PON1 Q192R with symptoms of depression in occupationally exposed groups may be driven by exposure to toxins that everyone in the general population is exposed to rather than exposure to toxins specifically used by sheep dippers or Gulf War veterans, or that other mechanisms underlie the association. This is because the study population in which we have found an association consisted of British women aged 60–79 years, few of whom were sheep dippers or Gulf War veterans. When using genotype–outcome associations to infer causality with respect to an environmental exposure modified by the genotype, it is important to examine these associations in general populations and in those specifically exposed to the putative agent. The possible role of PON1 Q192R in psychiatric morbidity requires further examination
Epistatic interaction between variations in the angiotensin I converting enzyme and angiotensin II type 1 receptor genes in relation to extent of coronary atherosclerosis
No full textOBJECTIVE: To test the hypothesis that gene-gene interaction of the renin-angiotensin system is associated with an effect on the extent of coronary atherosclerosis. SETTING AND RESULTS: A cohort of 1162 patients with coronary artery disease were genotyped for genetic polymorphisms in the renin-angiotensin system. Patients carrying the D allele of the angiotensin I converting enzyme (ACE) gene had greater coronary extent scores (defined as the number of coronary segments with 5% to 75% stenosis) than those not carrying this allele (p = 0.006 in non-parametric analysis and p = 0.019 in parametric analysis). This association remained significant after adjusting for age, body mass index, hypertension, and diabetes, which were also significantly associated with coronary extent scores. There was a significant interaction (p = 0.033) between genotypes of ACE and angiotensin II type 1 receptor (AGTR1). The association between the ACE gene D allele and increased coronary extent scores was significant (p = 0.008 in non-parametric and p = 0.027 in parametric analysis) in those carrying the +1166 C allele of the AGTR1 gene, but was absent in those not carrying the AGTR1 gene +1166 C allele. CONCLUSION: These findings suggest that variation in the ACE and AGTR1 genes and their interaction may not only contribute to susceptibility of coronary artery disease as previously found but also modify the disease process, thus contributing to interindividual differences in severity of the disease
Growth hormone-releasing factor (GRF) regulates expression of its own receptors
No full textRecent studies have demonstrated that passive immunization of neonatal rats to GRF inhibited their somatic growth through the suppression of GH secretion, In this study, we investigated the changes in pituitary GRF receptor (GRFR) expression in GRF antibody (GRF-ab) treated rats. Neonatal rats were treated from day 1 today 10 after birth with every other day sc injection of 50 mu l of normal rabbit serum (groups I: control & III) or rabbit serum containing GRF-ab (groups II & IV). In addition, groups III & IV received twice daily injection of recombinant human GH (0.4 mu g/kg, sc). The rats were sacrificed on day 11 and pituitaries were removed. The pituitary weights in all treatment groups were decreased compared to the control group (I). Total pituitary RNA was extracted and GRFR mRNA levels were determined by RNase protection assay. Receptor RNA levels were quantitated and normalized to an internal standard, glyceraldehyde 3-phosphate dehydrogenase (GAPDH). The ratios of GRFR mRNA to GAPDH mRNA were significantly decreased to 49.6 +/- 4.9 (mean +/- SD), 73.0 +/- 8.7, 43.6 +/- 9.5% of control group I in the experimental groups II, III, and IV, respectively (P<0.01). These data suggest that (1) suppression of GH secretion in GRF-ab heated animals was due, at least in pari, to a decrease in GRFR expression, (2) GRF may be necessary for ifs own receptor expression, (3) exogenous administration of GH suppresses pituitary GRFR mRNA
Oral History Interview with A. R. Evans
No full textThe National Museum of the Pacific War presents an oral monologue by A R Evans. Evans was the coastwatcher on Kolombangara who facilitated the rescue of the PT-109 crew, led by John F. Kennedy. One of his scouts noticed a fire on the water at night and saw an unidentified object floating the next day. Evans, having been informed that PT-109 was missing, instructed his scouts to search for crewmen. Two natives encountered the crew, who for want of a common language carved a message on a coconut to be delivered to Evans. Evans met Kennedy that afternoon and dispatched a message coordinating his safe return. When Evans visited the White House in 1961, he found a framed copy of the dispatch and the carved coconut in the Oval Office
- …
