619 research outputs found
Oriki Ogun (Praise of the God of Iron) by Mayowa Adeyemo
No full textLagos State University music student, Mayowa Adeyemo, praises Ogun (Yoruba Orisha/God of Iron). Recorded on July 26, 2013 at Peter King College of Music near Badagry, Lagos State. Keywords: African History; African Languages and Societies; Critical and Cultural Studies; Dance; Digital Humanities; Ethnic Studies; Ethnomusicology; Folklore; Gender, Race, Sexuality, and Ethnicity in Communication; Linguistic Anthropology; Oral History; Performance Studies; Poetry; Race and Ethnicity; Social and Cultural Anthropology; Sociology of Culture
A genome-wide search replicates evidence of a quantitative trait locus for circulating angiotensisn l-converting enzyme (ACE) unlinked to the ACE gene
No full textBackground: angiotensin I-converting enzyme (ACE) plays an important role in cardiovascular homeostasis. There is evidence from different ethnic groups that circulating ACE levels are influenced by a quantitative trait locus (QTL) at the ACE gene on chromosome 17. The finding of significant residual familial correlations in different ethnic groups, after accounting for this QTL, and the finding of support for linkage to a locus on chromosome 4 in Mexican-American families strongly suggest that there may well be QTLs for ACE unlinked to the ACE gene.Methods: a genome-wide panel of microsatellite markers, and a panel of biallelic polymorphisms in the ACE gene were typed in Nigerian families. Single locus models with fixed parameters were used to test for linkage to circulating ACE with and without adjustment for the effects of the ACE gene polymorphisms.Results: strong evidence was found for D17S2193 (Zmax = 3.5); other nearby markers on chromosome 17 also showed modest support. After adjustment for the effects of the ACE gene locus, evidence of "suggestive linkage" to circulating ACE was found for D4S1629 (Zmax = 2.2); this marker is very close to a locus previously shown to be linked to circulating ACE levels in Mexican-American families.Conclusion: in this report we have provided further support for the notion that there are QTLs for ACE unlinked to the ACE gene; our findings for chromosome 4, which appear to replicate the findings of a previous independent study, should be considered strong grounds for a more detailed examination of this region in the search for genes/variants which influence ACE levels.
The poor yields, thus far, in defining the genetic determinants of hypertension risk suggest a need to look beyond simple relationships between genotypes and the ultimate phenotype. In addition to incorporating information on important environmental exposures, a better understanding of the factors which influence the building blocks of the blood pressure homeostatic network is also required. Detailed studies of the genetic determinants of ACE, an important component of the renin-angiotensin system, have the potential to contribute to this strategic objectiv
An evangelical voice in Africa: the worldview background of the theology of Tokunboh Adeyemo (1 October 1944-17 March 2010)
No full textAfrica was blessed with a son of the calibre of Dr Tokunboh Adeyemo. Since he only recently passed away, we do not yet have (as far as the author is aware) an assessment of the legacy of this eminent Christian leader. This article is the first preliminary evaluation written from a reformational worldview perspective.
The set-up of the investigation is as follows: Firstly, a brief out- line is given of his life history, especially his training in the Evangelical tradition. Then, the décor (the overall situation of African Christianity) that was the background against which he lived and worked is painted. Thirdly, it is followed by the strengths and weaknesses of Evangelical Christianity of which Adeyemo was a representative. Fourthly, it is indicated how Adeyemo thought in line with post-Lausanne Evangelicalism. In the fifth place a preliminary worldview evaluation of his legacy is given. To assist possible future research a bibliography of his most important publications concludes the investigation
Time Index: Oriki Ogun (Praise of the God of Iron) by Mayowa Adeyemo
No full textThis file is the time index for " Oriki Ogun (Praise of the God of Iron) by Mayowa Adeyemo
The influence of age and sex on genetic associations with adult body size and shape: a large-scale genome-wide interaction study
No full textCorrected by Erratum: Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study, in PLoS Genetics,12(6):e1006166. The arcOGEN Consortium should be listed as an author of this article.Genome-wide association studies (GWAS) have identified more than 100 genetic variants contributing to BMI, a measure of body size, or waist-to-hip ratio (adjusted for BMI, WHRadjBMI), a measure of body shape. Body size and shape change as people grow older and these changes differ substantially between men and women. To systematically screen for age- and/or sex-specific effects of genetic variants on BMI and WHRadjBMI, we performed meta-analyses of 114 studies (up to 320,485 individuals of European descent) with genome-wide chip and/or Metabochip data by the Genetic Investigation of Anthropometric Traits (GIANT) Consortium. Each study tested the association of up to ~2.8M SNPs with BMI and WHRadjBMI in four strata (men ≤50y, men >50y, women ≤50y, women >50y) and summary statistics were combined in stratum-specific meta-analyses. We then screened for variants that showed age-specific effects (G x AGE), sex-specific effects (G x SEX) or age-specific effects that differed between men and women (G x AGE x SEX). For BMI, we identified 15 loci (11 previously established for main effects, four novel) that showed significant (FDR<5%) age-specific effects, of which 11 had larger effects in younger (<50y) than in older adults (≥50y). No sex-dependent effects were identified for BMI. For WHRadjBMI, we identified 44 loci (27 previously established for main effects, 17 novel) with sex-specific effects, of which 28 showed larger effects in women than in men, five showed larger effects in men than in women, and 11 showed opposite effects between sexes. No age-dependent effects were identified for WHRadjBMI. This is the first genome-wide interaction meta-analysis to report convincing evidence of age-dependent genetic effects on BMI. In addition, we confirm the sex-specificity of genetic effects on WHRadjBMI. These results may provide further insights into the biology that underlies weight change with age or the sexually dimorphism of body shape.Thomas W. Winkler ... Lyle J Palmer ... CHARGE Consortium, DIAGRAM Consortium, GLGC Consortium, Global-BPGen Consortium, ICBP Consortium, MAGIC Consortium ... et al
Foreign exchange market segmentation, foreign exchange utilisation and exchange rate votatility: the Nigerian experience
No full textThis article is on the exchange rate regime impact on the economic growth, inflation and external reserves of emerging economies. The author emphasized that Nigeria had a pegged exchange rate regime and strong exchange controls before the introduction of the Structural Adjustment Programme (SAP)
Fishermen cooperatives in the Green Revolution Programme
No full textThe aim of this study was to examine areas in which fishermen cooperatives can become involved and then suggest operational guidelines in order to increase fishermen income and also to make the Green Revolution Programme a success through increased production of fish. The paper enumerated different areas in which fishermen cooperatives can participate. These include: thrift and credits, thrift and savings, consumers and building cooperative societies. It is the belief of the author that the expansion of fishermen cooperatives into the areas mentioned in this paper can enable members to process and market their products more economically, buy supplies and equipment in large quantities and obtain lower cost credi
Fishermen cooperatives in the Green Revolution Programme
No full textThe aim of this study was to examine areas in which fishermen cooperatives can become involved and then suggest operational guidelines in order to increase fishermen income and also to make the Green Revolution Programme a success through increased production of fish. The paper enumerated different areas in which fishermen cooperatives can participate. These include: thrift and credits, thrift and savings, consumers and building cooperative societies. It is the belief of the author that the expansion of fishermen cooperatives into the areas mentioned in this paper can enable members to process and market their products more economically, buy supplies and equipment in large quantities and obtain lower cost credi
Unexplained wealth and financial crime: A global perspective
No full textThis book considers the growing and emerging issue of unexplained wealth and how this issue fits within the larger challenge of financial and economic crime. The collection provides a rich and robust contribution to the dearth of knowledge in this space. Contributions are drawn from legal practitioners, academics and experts from the Global South, Global North, and the Asia Pacific who share their insights to the methods and approaches that have been utilised to tackle unexplained wealth in their respective countries. Each author provides a comprehensive critique of the current regime in addressing the issue and identifies failings. The volume further considers how unexplained wealth can be recognised as an important category, similar in this respect to fraud, bribery, corruption, and tax evasion amongst others. Establishing the issue of unexplained wealth as an independent area of research, the book will be essential reading for researchers, academics and policy-makers working in the areas of financial and economic crime, banking law and international corporate governance
Genetic studies of African populations: an overview on disease susceptibility and response to vaccines and therapeutics.
No full textAfrica is the ultimate source of modern humans and as such harbors more genetic variation than any other continent. For this reason, studies of the patterns of genetic variation in African populations are crucial to understanding how genes affect phenotypic variation, including disease predisposition. In addition, the patterns of extant genetic variation in Africa are important for understanding how genetic variation affects infectious diseases that are a major problem in Africa, such as malaria, tuberculosis, schistosomiasis, and HIV/AIDS. Therefore, elucidating the role that genetic susceptibility to infectious diseases plays is critical to improving the health of people in Africa. It is also of note that recent and ongoing social and cultural changes in sub-Saharan Africa have increased the prevalence of non-communicable diseases that will also require genetic analyses to improve disease prevention and treatment. In this review we give special attention to many of the past and ongoing studies, emphasizing those in Sub-Saharan Africans that address the role of genetic variation in human disease
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