9 research outputs found
"It takes a village": Integrating nurse practitioners in childhood mental health care
This literature review analyses how nurse practitioners can assist childhood mental health as led by the research question “What interventions can be implemented by NPs in a primary care setting for children 0-5 years old that are exhibiting internalizing/externalizing behaviours?” To answer this question, 10 research studies were analysed using a literature review matrix as guided using the steps of problem identification, literature search, data evaluation, data analysis, and presentation, which focuses on the interpretation of the findings, discussion, and recommendations for practice. Final recommendations are based around the two themes of parental change and health promotion through education and screening. Parental change is implemented through parenting classes, regular attendance of appointments and classes, and using local or online resources. Health promotion through education of childhood milestones and internalizing and externalizing behaviours and the consistent use of screening tools in well-child visits. This review emphasizes the benefits of an NP being involved in childhood mental health care
Development and in-flight demonstration of ?E-CATS?, an experimental embedded training system for fighter aircraft
Is gauche attraction between the fluoro atom and the incoming nucleophile really the determining factor in cissoid stereochemistry?
Synthesis and properties of 5-fluoro-6-alkoxy uracil derivatives; formation of a high amount of ‘anti-gauche’ products.
ChemInform Abstract: Fluorinated Pyrimidines. Part 4. Synthesis, Properties and Stereochemical Conversion of the cis and trans Isomers of 6-Alkoxy-5- fluoro-5,6-dihydrouracils.
In vitro antitumour activity of cis- and trans-5-fluoro-5,6-dihydro-6-alkoxy-uracils; effects on thymidylate synthesis
The development of a glucose prediction model in critically ill patients
Purpose: The aim of the current study is to develop a prediction model for glucose levels applicable for all patients admitted to the ICU with an expected ICU stay of at least 24 h. This model will be incorporated in a closed-loop glucose system to continuously and automatically control glucose values.Methods: Data from a previous single-center randomized controlled study was used. All patients received a FreeStyle Navigator II subcutaneous CGM system from Abbott during their ICU stay.The total dataset was randomly divided into a training set and a validation set. A glucose prediction model was developed based on historical glucose data. Accuracy of the prediction model was determined using the Mean Squared Difference (MSD), the Mean Absolute Difference (MAD) and a Clarke Error Grid (CEG).Results: The dataset included 94 ICU patients with a total of 134,673 glucose measurements points that were used for modelling. MSD was 0.410 +/- 0.495 for the model, the MAD was 5.19 +/- 2.63 and in the CEG 99.8% of the data points were in the clinically acceptable regions.Conclusion: In this study a glucose prediction model for ICU patients is developed. This study shows that it is possible to accurately predict a patient's glucose 30 min ahead based on historical glucose data. This is the first step in the development of a closed-loop glucose system. (C) 2021 Elsevier B.V. All rights reserved.</p
