76,341 research outputs found
Read [PDF] Books A Visual Dictionary of Architecture [Full]
No full textRead Or Download A Visual Dictionary of Architecture Full Books By by {"isAjaxComplete_B001H6NK1W":"0","isAjaxInProgress_B001H6NK1W":"0"} Francis D. K. Ching (Author) › Visit Amazon's Francis D. K. Ching Page Find all the books, read about the author, and more. See search results for this author Are you an author? Learn about Author Central Francis D. K. Ching (Author)
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Comments on: Lyman, Lee R. 2009. “Review of Artifact Classification: A Conceptual and Methodological Approach, by Dwight Read” Journal of Anthropological Research 65:111-113
No full textA good book review provides documentation for its evaluations, especially when they are either very positive or very negative. A good review is also faithful to what the author has written and bases criticisms or praise on accurate paraphrasing or quotes from the book. This review by Lyman fails on both accounts. Critical comments are not documented and the review is based on what Lyman imagines Read to have written, not what Read actually wrote
Read, R H R J, NX2791
No full textThis record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/412496Surname: READ. Given Name(s) or Initials: R H R J. Military Service Number or Last Known Location: NX2791. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 4146.229206
Item: [2016.0049.44758] "Read, R H R J, NX2791
Defining the role of SF3B1K700E mutations in ER+ breast cancer
No full textMutations in SF3B1, a component of the RNA splicing machinery, underpin a number of aggressive cancers. Hotspot mutations in SF3B1 are present in around 3% of breast cancers, are enriched in oestrogen receptor positive disease, and are associated with a poor prognosis. Investigation identified an enrichment of SF3B1K700E binding with Era, aberrant splicing of ER target genes, and a global rewiring of ERA chromatin binding in SF3B1K700E breast cancer cells which suggest these cells are in a primed state to develop resistance to endocrine therapies. To investigate the functional consequences of the SF3B1K700E mutation, a synthetic lethal gene silencing screen was utilised which identified tumour suppressor like genes that could be contributing to SF3B1K700E tumorigenesis, such as BRD9. In addition, a high throughput drug screen was utilised to identify novel therapeutic options for patients with SF3B1K700E mutant cancers. This identified the PARP inhibitor, talazoparib, to selectively kill SF3B1K700E cells. Further interactome analysis identified increased interactions of PARP1, the FACT complex, SF3B1K700E, and H3K4me3. This is suggestive of an adaption of the co-transcriptional splicing program to the burden of the hotspot SF3B1K700E mutation. Indeed, this could be exploited utilising PARP and FACT complex inhibitor combination treatment that synergise in SF3B1K700E cells. In summary, this thesis research has identified a possible rationale for SF3B1K700E enrichment in ER+ breast cancers and a therapeutic strategy for patients with talazoparib (approved in TNBC) and FACT complex inhibitors (in phase I clinical trials)
Reading the Word and the World in Haiti: Literacy Education for Social Justice
No full textThe first author traveled to Haiti as a member of a group of volunteers from the U.S. whose goals were to provide assistance to children in a privately operated primary school located in the rural community of Lamardelle. For the first author, assistance primarily focused on training in literacy education, with an emphasis on reading comprehension strategies for students who struggle to read. We examine literacy education as a tool of social justice. This paper describes the components of the first summer of this teacher development program and explains how our work was undergirded by the Freirean ideas regarding liberatory education (Frire,2000). A second aim is to analyze ways language impacts the practice of education in Haiti. In so doing we hope to present a model of how literacy education can be a tool for social justice in similar contexts
Read, L R, 407277
No full textThis record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/412483Surname: READ. Given Name(s) or Initials: L R. Military Service Number or Last Known Location: 407277. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 9620.229193
Item: [2016.0049.44745] "Read, L R, 407277
Reading in the mobile era
No full textMobile technology can advance literacy and learning in underserved communities around the world.
Summary
Millions of people do not read for one reason: they do not have access to text. But today mobile phones and cellular networks are transforming a scarce resource into an abundant one.
Drawing on the analysis of over 4,000 surveys collected in seven developing countries and corresponding qualitative interviews, this report paints the most detailed picture to date of who reads books and stories on mobile devices and why.
The findings illuminate, for the first time, the habits, beliefs and profiles of mobile readers. This information points to strategies to expand mobile reading and, by extension, the educational, social and economic benefits associated with increased reading.
Mobile technology can advance literacy and learning in underserved communities around the world. This report shows how
The XMM-Newton Slew view of IGRJ17361-4441: a transient in the globular cluster NGC 6388.
No full textIGRJ17361-4441 is a hard transient recently observed by the INTEGRAL satellite. The source, close to the center of gravity of the globular cluster NGC 6388, quickly became the target of follow-up observations conducted by the Chandra, Swift/XRT and RXTE observatories. Here, we concentrate in particular on a set of observations conducted by the XMM-Newton satellite during two slews, to get the spectral information of the source and search for spectral variations. The spectral parameters determined by the recent XMM-Newton slew observations were compared to the previously known results. The maximum unabsorbed X-ray flux in the 0.5-10 keV band as detected by the XMM-Newton slew observations is ≃4.5 × 10-11 erg cm-2 s-1; i.e., it is consistent with that observed by the Swift/XRT satellite 15 days earlier. The spectrum seems to be marginally consistent (Γ ≃ 0.93 - 1.63) with what has been derived from the previous high-energy observations
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