1,720,974 research outputs found

    Tricuspid valve repair in an infant with multiple obstructive andida mycetomas.

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    Neonatal fungal valve endocarditis is an uncommon and highly lethal disease. The ideal management strategy is still controversial. Current options include antifungal chemotherapy and surgical intervention, the latter being often limited by risks inherent with valve operations in low body weight infants. We present a case of a premature infant with mutliple Candida tricuspid valve mycetomas. Eradication of infection was achieved by combined liposomal amphotericin therapy and complex tricuspid valve repair. Indications, technical aspects, and outcome of treatment in infants are reviewed

    Fate of the aortic root late after Ross operation.

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    Background - The Ross operation is an alternative to mechanical aortic valve replacement in the young. Early dilatation of the pulmonary autograft root exposed to the systemic circulation has been reported. To define the prevalence of, risk factors for, and consequences of late autograft dilatation, outcome in all consecutive patients operated since May 1994 was reviewed. Methods and Results - Ninety one patients, 77 males and 14 females, with at least 1 year of follow-up underwent cross-sectional clinical and echocardiographic examination. Age at operation was 27 +/- 10 years ( range 6 to 49), and the indication was aortic regurgitation in 54 ( 59%) patients and bicuspid valve was present in 62 ( 68%). End-points of the study were freedom from autograft dilatation (root diameter > 4 cm or 0.21 cm/m(2)), from (moderate) autograft regurgitation and from reoperation. Follow-up (4.0 +/- 1.9, range 1 to 8 years) autograft root diameters were anulus, 29 +/- 4 mm (18 - 39); sinus of Valsalva, 38 +/- 7 mm (24 - 53); sinotubular junction, 37 +/- 6 mm ( 23 - 54); and ascending aorta, 37 +/- 5 mm (27 - 54). Late autograft dilatation was identified in 31 (34%) patients and regurgitation in 13 (14%), 7 of whom had autograft dilatation. At 7 years, freedom from dilatation was 42 +/- 8%, freedom from regurgitation was 75 +/- 8%, and freedom from reoperation was 85 +/- 10%. Cox proportional hazard analysis identified younger age ( P = 0.05), preoperative sinus of Valsalva ( P = 0.02), root replacement technique ( P = 0.03), and absence of pericardial buttressing ( P = 0.04) as predictive of autograft dilatation, whereas female sex (P = 0.002), follow-up sinus of Valsalva ( P = 0.003), and sinotubular junction diameter ( P = 0.02) as predictive of autograft regurgitation. Conclusions - Autograft dilatation is common late after the Ross procedure, particularly in younger patients, in those with preoperative aortic aneurysm, and those having root replacement without support of anulus and sinotubular junction. Bicuspid aortic valve is not a risk factor. Significant autograft valve dysfunction affects a minority of patients, but it is more prevalent in those with autograft dilatation

    Uncorrected Ebstein's anomaly with atrial septal defect complicated by brain abscess in an adult patient

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    We report the case of a 56-year-old male patient affected by a severe form of Ebstein's anomaly (type C of Carpentier classification) with secundum atrial septal defect, who presented to the emergency department with impaired consciousness, seizures, and trismus. The brain computed tomography scan showed evidence of a mass located in the frontal lobe, confirmed by brain MRI consistent with brain abscess. Both echocardiography and cardiac MRI showed no evidence of valvular vegetation. This case shows how the combination of increased atrial pressure and bidirectional shunt through atrial septal defect may lead to paradoxical embolization
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