1,721,160 research outputs found
Effusides I-V: 9,10-dihydrophenanthrene glucosides from Juncus effusus
No full textFive 9,10-dihydrophenanthrene glucosides, named effusides I-V, have been isolated from the methanolic extract of Juncus effusus. Structures have been determined on spectroscopic grounds. © 1995
Bioconversion of 17 beta-hydroxy-17 alpha-methyl-androsta-1,4-dien-3-one and androsta-1,4-diene-3,17-dione in cultures of the green alga T76 Scenedesmus quadricauda
No full textExogenous 17β-hydroxy-17α-methyl-androsta-1,4-dien-3-one and androsta-1,4-diene-3,17-dione are biotransformed by the green alga T76 Scenedesmus quadricauda. The bioproducts have been isolated by chromatographic processes and identified on the basis of their spectroscopic features. Hydration of the Δ4 double bond may justify the presence of the epimeric 5-hydroxyderivatives while rather complex skeleton rearrangements are involved in the formation of the remaining products
OLEANANE GLYCOSIDES FROM HYDROCOTYLE RANUNCULOIDES
No full textSix new oleanane glycosides, ranuncosides I-VI, have been isolated from Hydrocotyle ranunculoides. Their structures have been determined on the basis of chemical and spectroscopic studies. © 1994
Structure activity relationships of phenylpropanoids as growth inhibithors of the green alga Selenastrum capricornutum.
No full textJuncoside I,A New Cycloartanelactone Glucoside From Juncus Effusus
No full textA new cycloartanelactone glucoside, Juncoside I, has been isolated from Juncus effusus anM its structure has been determined by chemical and spectroscopic studies.Key Words. Juncus effusus,Juncaceae, cycloartane glucoside, 3j3-hydroxy-cycloart-24Z-ene-22(S)—»26 lactone, Juncoside I. © 1994 Harwood Academic Publishers GmbH
TETRAHYDROPYRENE GLUCOSIDES FROM JUNCUS-EFFUSUS
No full textTwo tetrahydropyrene glucosides have been isolated from Juncus effuses and their structures determined by spectroscopic analysis and hemisynthesis. © 1995, Taylor & Francis Group, LLC. All rights reserved
A multispecies study to assess the toxic and genotoxic effect of pharmaceuticals: Furosemide and its photoproduct
No full textPharmaceutical products for humans and animals, as well as their related metabolites end up in the aquatic environment after use. Recent investigations show that concentrations of pharmaceuticals are detectable in the order of ng/l-μg/l in municipal wastewater, groundwater and also drinking water. Little is known about the effects, and the hazard of long-term exposure to low concentrations of pharmaceuticals for non-target aquatic organisms. This study was designed to assess the ecotoxicity of furosemide, a potent diuretic agent, and its photoproduct in the aquatic environment. Bioassays were performed on bacteria, algae, rotifers and microcrustaceans to assess acute and chronic toxicity, while the SOS Chromotest and the Ames test were utilized to detect the genotoxic potential of the investigated compounds. A first approach to risk characterization was to calculate the environmental impact of furosemide by measured environmental concentration and predicted no effect concentration ratio (MEC/PNEC). To do so we used occurrence data reported in the literature and our toxicity results. The results showed that acute toxicity was in the order of mg/l for the crustaceans and absent for bacteria and rotifers. Chronic exposure to these compounds caused inhibition of growth population on the consumers, while the algae did not seem to be affected. A mutagenic potential was found for the photoproduct compared to the parental compound suggesting that byproducts ought to be considered in the environmental assessment of drugs. The risk calculated for furosemide suggested its harmlessness on the aquatic compartment. © 2005 Elsevier Ltd. All rights reserved
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