2 research outputs found
Palliative care for patients after surgical resection for high-grade central nervous system tumors / Cuidados paliativos para pacientes após ressecção cirúrgica de tumores de alto grau do sistema nervoso central
Purpose: to analyze palliative care following surgical resection in patients with high-grade central nervous system tumors. Methods: integrative literature review conducted in the MEDLINE database via PubMed, Scopus, and Web of Science, with no restrictions on language or year of publication. Results: key themes identified include neurosurgical needs, symptom relief, care subdivisions, and multiprofessional involvement. The positive impact of palliative care on patient quality of life and disease progression, from diagnosis to end-of-life, was highlighted. Conclusion: early and well-implemented palliative care reduces unnecessary hospital admissions, provides physical, psychological, social, and spiritual support, and benefits both patients and families. The implementation of public policies and training programs is recommended to improve access to this essential care.Objetivo: analizar los cuidados paliativos después de la resección quirúrgica en pacientes con tumores de alto grado del sistema nervioso central. Métodos: revisión integrativa de la literatura realizada en las bases de datos MEDLINE vía PubMed, Scopus y Web of Science, sin restricciones de idioma ni año de publicación. Resultados: se identificaron temas clave como necesidades neuroquirúrgicas, alivio de síntomas, subdivisiones de cuidado y participación multiprofesional. Se destacó el impacto positivo de los cuidados paliativos en la calidad de vida de los pacientes y en el progreso de la enfermedad, desde el diagnóstico hasta el final de la vida. Conclusión: los cuidados paliativos precoces y bien implementados reducen hospitalizaciones innecesarias, brindan apoyo físico, psicológico, social y espiritual, y benefician tanto a pacientes como a familias. Se recomienda implementar políticas públicas y programas de formación para ampliar el acceso a este cuidado esencial.Objetivo: analisar os cuidados paliativos após ressecção cirúrgica em pacientes com tumores de alto grau do sistema nervoso central. Método: revisão integrativa da literatura realizada nas bases de dados MEDLINE via PubMed, Scopus e Web of Science, sem restrições de idioma ou ano de publicação. Resultados: a análise identificou temas relevantes, como a necessidade de neurocirurgia, alívio de sintomas, subdivisões de cuidado e envolvimento multiprofissional. Destaca-se o impacto positivo dos cuidados paliativos na qualidade de vida dos pacientes e no curso da doença, desde o diagnóstico até o final da vida. Conclusão: cuidados paliativos precoces e bem executados reduzem internações desnecessárias, promovem suporte físico, psicológico, social e espiritual, e beneficiam pacientes e familiares. Recomenda-se a implementação de políticas públicas e programas de treinamento para ampliar o acesso a este cuidado essencial.
Physical Exercise as a Modulator of the Levels of Leptin/Adiponectin Relation and Inflammation in Chronic Kidney Disease
Chronic kidney disease (CKD) is an important factor of loss of quality of life and high rates of morbidity and mortality, where cardiovascular diseases are the main responsible for this poorer prognosis. It is verified that CKD is associated with high inflammatory levels in the body, or that it seems to contribute to these cardiovascular events. Thus, CKD is characterized by a high inflammatory profile, as well as possibly a large imbalance in adipokines due to changes in body composition. Thus, adiponectin and leptin emerge as possible inflammatory modulators, although their popular effects are not completely elucidated. On the other hand, it is proven that physical exercise can be a great tool in the treatment of CKD and in the modulation of biomarkers, stimulating in an anti-inflammatory way and promoting an adjustment in the main causes of morbidity and mortality in this population. Thus, this review seeks to elucidate the role of exercise as a modulator of inflammation and the leptin/adiponectin relationship in order to contribute to the better quality of life of this population, in addition to demonstrating the important role that exercise can exert in modulation of these biomarkers, aiming to minimize the cardiovascular effects that these biomarkers exert on this population
