89,795 research outputs found
Manuale pratico di oncologia. Fondamenti per il medico non oncologo- Costanzo Francesco; Cognetti Francesco; Benedetti Panici Pierluigi
No full textBenedetti Panici P, Di Donato V., Fischetti M, Lo Prete E, Musella A, Plotti F, Casorelli A, Bellati F (2011).
Capitoli: Carcinoma Dell' Endometrio.. arcinoma Epiteliale Dell’ovaio In: -. Manuale Pratico Di Oncologia Fondamenti Per Il Medico Non Oncologo
Collezionismo a Modena e Reggio tra Otto e Novecento
No full textIl contributo, dedicato alle Mostre di Arte antica organizzare a Reggio Emilia nel 1876 e nel 1899 e a Modena nel 1906, offre una nuova testimonianza, oltre agli studi da tempo avviati sulle raccolte d'arte delle due città estensi, per approfondire la vivace realtà del collezionismo privato di questi luoghi, tra la fine dell'Ottocento e i primi anni del Novecento
Response to Comment on "Robotic Versus Laparoscopic Surgery for Rectal Cancer: An Evidence-based Approach"
No full textTra Innominato e Macbetto: Il cappello del prete di Emilio De Marchi.
No full textINFLUENZA DELLE TEMATICHE DEL MACBETH SUL ROMANZO DI DE MARCHI Il cappello del prete E SULLA NARRATIVA DI FINE OTTOCENT
Complete subcutaneous rupture of the patellar tendon: Epidemiological and treatment problems in athletes
No full textE. Verni, F. Catani, R. Beluzzi, G. Del Prete, L. Prosperi, and R. Buda: Complete subcutaneous rupture of the patellar tendon: epidemiological and treatment problems in athletes. J. Sports Traumatol. rel. res. 19: 38, 1997. An account is given of 14 cases of patellar tendon rupture observed in 10 years with a minimum follow-up of 18 months. All athletes were treated with the same surgical technique. In addition to providing temporary protection for the tendon suture, cerclage is a sound means of securing the correct position of the patella. The results show that resumption of sport is a more selective criterion than modem clinical and instrumental investigations. The common epidemiological denominator was eccentric pliometric power training. In the absence of controlled scientific data concerning this form of functional overuse, careful selection and periodic monitoring is required of athletes whose explosive force is to be increased through previous stretching of a muscle
CD20-depleting therapy in autoimmune diseases: from basic research to the clinic
No full textPerosa F, Prete M, Racanelli V, Dammacco F (University of Bari Medical School, Bari, Italy). CD20-depleting therapy in autoimmune diseases: from basic research to the clinic (Review). J Intern Med 2010; 267: 260-277. The B lymphocyte-associated antigen CD20 is becoming an important immunotherapy target for autoimmune diseases, although its biological function has not been defined. Besides rheumatoid arthritis, growing experience with B cell-depleting therapy indicates that it may be effective in Sjögren's syndrome, dermatomyositis-polymyositis, systemic lupus erythematosus and some types of vasculitides. However, controlled clinical trials are still lacking for some of these indications. Infection has not been seen as a major limitation to this therapy, but reports of progressive multifocal leukoencephalopathy in an extremely small number of patients are of concern. Here, we review the therapeutic actions of anti-CD20 antibodies, and the recent and ongoing clinical trials with CD20-depleting therapy in autoimmune diseases. © 2010 Blackwell Publishing Ltd
Human CD4 internal antigen anti-idiotypic monoclonal antibody. Immunochemical and sequence analysis
No full textThe mouse mAb2 16D7 recognizes the paratope of the syngeneic anti-human CD4 mAb HP2/6 (mAb1 of our idiotypic cascade) and mimics CD4 in xenogeneic settings in humans. Immunochemical and sequence analyses were performed to define the minimum structural requirement for this mimicry. Binding assay of mAb1 with isolated naive 16D7 H and L chains showed that only the second reacted with mAb1. Specificity was indicated by the lack of reactivity of mAb1 with the L chain of mAb2 14D6, which also recognizes mAb1-paratope. It is likely that the 16D7-L mAb1-specific epitope is "sequence-dependent", since fully denatured 16D7-L still reacted with mAb1. Sequence analysis of 16D7 and mAb1 showed a high degree of homology of their VH, as both were coded by the same gene family (V/II), whereas CDR3 showed the greatest diversity. Alignment of 16D7-H CDR3 with CD4, however, produced no similarity. In contrast, analyses of the 16D7 VL sequence (XX/V) defined a CDR3 6-mer peptide with a 50% identity (83% of similarity) to the CD4 stretch 218-223. This peptide seems a suitable replacement for 16D7 in active immunotherapy as it did not match any protein fragment retrieved from the n-r database (NCBI) and both the peptide and the corresponding CD4 amino acid stretch are surface accessible. Based on their immunochemical profiles and similarity to CD4, four additional 16D7-derived peptides were designed for synthesis. The data indicate that CD4 mimicry by mAb2 can be obtained at the level of primary structure and provide useful information for the synthesis of peptide(s) with bioactive potential
F. Gaudioso, Un prete notaio d'antico regime. I protocolli di Domenico Diego de Monte Notaio apostolico in terra d'Otranto (1697-1732), 1991
No full textRoland Minnerath. F. Gaudioso, Un prete notaio d'antico regime. I protocolli di Domenico Diego de Monte Notaio apostolico in terra d'Otranto (1697-1732), 1991. In: Revue des Sciences Religieuses, tome 68, fascicule 3, 1994. Produire. p. 382
Il collezionismo privato e le mostre d’arte antica in Italia fra Otto e Novecento
No full textATTI DELLE GIORNATE DI STUDIO a cura di R. Varese, F. Veratell
Explaining the use of performance information by public managers: Do task-related factors matter?
No full textOrganizational factors have frequently shown a significant influence on the use of performance information by public managers, but the study of task-related factors has been neglected. Combining insights from public administration, organizational studies, and a behavioural approach, this article investigates whether some task characteristics influence the use of performance information by public managers. Drawing on an e-mail survey on managers working in Italian medium-size municipalities, an empirical analysis was developed. Findings show that task analysability and task variability directly affect performance information use by public managers. Task interdependence shows an indirect effect on performance information use through its availability
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