39 research outputs found
Lymphadenectomy in hypopharyngeal cancer % correlation of micrometastatic spread with predictive molecular markers of therapeutic response
No full textUvod: Skvamocelularni karcinom hipofarinksa (SKH) predstavlja jednu od najagresivnijih neoplazmi glave i vrata. Petogodišnje preţivljavanje kod ovog oboljenja u većini studija je ispod 30%. Zahvaćenost limfnih ţlezda prepoznata je kao nabitniji prognostiĉki faktor za SKH. Hirurško leĉenje SKH stoga treba orijentisati prema odstranjenju primarnog tumora, ali i adekvatnoj limfonodalnoj disekciji, ĉime bi se postigao potencijalni kurativni efekat, ali i odredio taĉan stadijum i prognoza oboljenja.
Uniformno radikalno operisana grupa bolesnika i veliki broj odstranjenih limfnih nodusa omogućio nam je adekvatno odreĊivanje distribucije limfonodalnih metastaza, procene N stadijuma bolesti, ali i dodatnu imunohistohemijsku analizu na prisustvo mikrometastaza u odstranjenim limfnim nodusima. Dodatnim ispitivanjem pokušali smo da ustanovimo korelaciju ekspresije molekularnih markera p53 i EGFR sa preţivljavanjem, i stadijumom bolesti odraţenim prevashodno kroz N stadijum bolesti.
Metodologija: U studiju je ukljuĉeno ukupno 55 bolesnika kod kojih je naĉinjena faringolaringoezofagektomija sa funkcionalnom disekcijom vrata i rekonstrukcija visceralnim transplantatom. Disekcija obe strane vrata je uĉinjena primenom lateralne selektivne disekcije koja je obuhvatala uklanjanje limfnih nodusa iz nivoa II, III, IV i VI . Prilikom patohistološke obrade preparata posebna paţnja je obraćena na sledeće parametre:1. Primarna lokalizacija tumora (mukozna distribucija i dubina infiltracije, diferencijacija, invazija vaskularnih, limfatiĉnih i neuralnih elemenata), 2. Nodalni status (ukupan broj odstranjenih nodusa, ukupan broj pozitivnih nodusa, prisustvo ektrakapsularnog rasta, veliĉina nodusa). Dodatnom imunohistohemijskom analizom ispitivani su limfni nodusi na prisustvo mikrometastaza i izolovanih tumorskih ćelija, odnosno uĉinjena je semikvantitativna procena ekspresija ispitivanih
6
markera (p53 i EGFR). Statistiĉkim analizama naĉinjena je korelacija gore navedenih parametara sa ukupnim preţivljavanjem i kliniĉkim ishodom pri završetku studije...Introduction: Hypopharyngeal squamocellular carcinoma (HSCC) represents one of the most aggressive neoplastic diseases of head and neck. Most of the studies reports 5 year survival rate to be below 30%. Lymph node involvement in HSCC has been recognized as the most important prognostic factor. Surgical treatment of HSCC therefore should be oriented towards removal of the primary tumor, together with the adequate lymhonodal dissection, by which one accomplishes curative intent, both with the proper definite disease staging and prognosis.
Uniformly radically operated group of patients and a large number of dissected lymph nodes provided us with a possibility of accurate estimation of lymph node distribution, accurate N staging and also allowed us additional immunohistochemical analyzes for presence of micrometastases in lymph nodes. With further investigation we will try to estimate the correlation between molecular expression of p53 and EGFR with the overall survival, and the disease stage.
Methodology: Overall, in this study we included 55 patients in whom pharyngolaryngoesophagectomy with selective lymph node dissection and reconstruction with the visceral substituent was performed. We performed bilateral selective lymph node dissection, which included levels II, III, IV and VI. During the pathohistologic work up special emphasis was given upon: 1. primary tumor (mucosal distribution and the depth of infiltration, differentiation and invasion of vascular, lymphatic and neural elements), 2. nodal status (overall number of harvested lymh nodes, overall number of positive lymph nodes, size and presence of extracapsular growth). Immunohistochemistry was performed in order to determine presence of micrometastases and isolated tumor cels (ITC) in lymph nodes, and also to determine the expression of p53 and EGFR. Statistical analyzes were performed with the intent to determine the correlation of the aforementioned parameters with the overall survival rate.
Results: In this study there was no intrahospital mortality. Overall survival median was 18.00 months (11,89 - 24,11). 42 (76%) patients died and 13 (24%) was alive when we ended the study. Two year survival was marked in 27 patients (46.5%). N0 stage was present in 17 patients, 8
9
patients had N1 stage while N2 stage was present in 30 patients..
Lymphadenectomy in hypopharyngeal cancer % correlation of micrometastatic spread with predictive molecular markers of therapeutic response
No full textUvod: Skvamocelularni karcinom hipofarinksa (SKH) predstavlja jednu od najagresivnijih neoplazmi glave i vrata. Petogodišnje preţivljavanje kod ovog oboljenja u većini studija je ispod 30%. Zahvaćenost limfnih ţlezda prepoznata je kao nabitniji prognostiĉki faktor za SKH. Hirurško leĉenje SKH stoga treba orijentisati prema odstranjenju primarnog tumora, ali i adekvatnoj limfonodalnoj disekciji, ĉime bi se postigao potencijalni kurativni efekat, ali i odredio taĉan stadijum i prognoza oboljenja.
Uniformno radikalno operisana grupa bolesnika i veliki broj odstranjenih limfnih nodusa omogućio nam je adekvatno odreĊivanje distribucije limfonodalnih metastaza, procene N stadijuma bolesti, ali i dodatnu imunohistohemijsku analizu na prisustvo mikrometastaza u odstranjenim limfnim nodusima. Dodatnim ispitivanjem pokušali smo da ustanovimo korelaciju ekspresije molekularnih markera p53 i EGFR sa preţivljavanjem, i stadijumom bolesti odraţenim prevashodno kroz N stadijum bolesti.
Metodologija: U studiju je ukljuĉeno ukupno 55 bolesnika kod kojih je naĉinjena faringolaringoezofagektomija sa funkcionalnom disekcijom vrata i rekonstrukcija visceralnim transplantatom. Disekcija obe strane vrata je uĉinjena primenom lateralne selektivne disekcije koja je obuhvatala uklanjanje limfnih nodusa iz nivoa II, III, IV i VI . Prilikom patohistološke obrade preparata posebna paţnja je obraćena na sledeće parametre:1. Primarna lokalizacija tumora (mukozna distribucija i dubina infiltracije, diferencijacija, invazija vaskularnih, limfatiĉnih i neuralnih elemenata), 2. Nodalni status (ukupan broj odstranjenih nodusa, ukupan broj pozitivnih nodusa, prisustvo ektrakapsularnog rasta, veliĉina nodusa). Dodatnom imunohistohemijskom analizom ispitivani su limfni nodusi na prisustvo mikrometastaza i izolovanih tumorskih ćelija, odnosno uĉinjena je semikvantitativna procena ekspresija ispitivanih
6
markera (p53 i EGFR). Statistiĉkim analizama naĉinjena je korelacija gore navedenih parametara sa ukupnim preţivljavanjem i kliniĉkim ishodom pri završetku studije...Introduction: Hypopharyngeal squamocellular carcinoma (HSCC) represents one of the most aggressive neoplastic diseases of head and neck. Most of the studies reports 5 year survival rate to be below 30%. Lymph node involvement in HSCC has been recognized as the most important prognostic factor. Surgical treatment of HSCC therefore should be oriented towards removal of the primary tumor, together with the adequate lymhonodal dissection, by which one accomplishes curative intent, both with the proper definite disease staging and prognosis.
Uniformly radically operated group of patients and a large number of dissected lymph nodes provided us with a possibility of accurate estimation of lymph node distribution, accurate N staging and also allowed us additional immunohistochemical analyzes for presence of micrometastases in lymph nodes. With further investigation we will try to estimate the correlation between molecular expression of p53 and EGFR with the overall survival, and the disease stage.
Methodology: Overall, in this study we included 55 patients in whom pharyngolaryngoesophagectomy with selective lymph node dissection and reconstruction with the visceral substituent was performed. We performed bilateral selective lymph node dissection, which included levels II, III, IV and VI. During the pathohistologic work up special emphasis was given upon: 1. primary tumor (mucosal distribution and the depth of infiltration, differentiation and invasion of vascular, lymphatic and neural elements), 2. nodal status (overall number of harvested lymh nodes, overall number of positive lymph nodes, size and presence of extracapsular growth). Immunohistochemistry was performed in order to determine presence of micrometastases and isolated tumor cels (ITC) in lymph nodes, and also to determine the expression of p53 and EGFR. Statistical analyzes were performed with the intent to determine the correlation of the aforementioned parameters with the overall survival rate.
Results: In this study there was no intrahospital mortality. Overall survival median was 18.00 months (11,89 - 24,11). 42 (76%) patients died and 13 (24%) was alive when we ended the study. Two year survival was marked in 27 patients (46.5%). N0 stage was present in 17 patients, 8
9
patients had N1 stage while N2 stage was present in 30 patients..
Meeting Children’s Author Julia Donaldson
No full textA report from a meet and greet with Julia Donaldson, a best-selling children's author. The event was organized by Ibis grafika publishing house and held in bookshop "Bookara" in Zagreb, 20 May 2018
Significance of KIT and PDGFRA gene mutation in evaluation of surgically treated gastric gastrointestinal stromal tumor patients
No full textCilj: Ispitivanje genetskih mutacija na KIT i PDGFRA genima, prikazivanje njihove učestalosti, vrste
mutacija i korelacije ovih specifičnih genskih mutacija sa patohistološkim i imunohistohemijskim
karakteristikama tumora. Korelacija genetskih mutacija na KIT i PDGFRA sa kliničkim tokom operisanih
bolesnika.
Metod: Prospektivna i delimično retrospektivna klinička studija koja je uključila 100 bolesnika operisane
zbog GIST-a želuca u period od 2005 do 2016 godine. Načinjena je molekularna analiza na parafinskim
kalupima tumorskog tkiva, a kod 45 bolesnika kod kojih su identifikovane KIT i PDGFRA mutacije
sprovedena je dalja analiza, sa posebnim osvrtom na patološke karakteristike tumora, recidiv oboljenja i
ukupno preživljavanje, te procena uticaja analiziranih genskih mutacija na navedene promene.
Rezultati: Od 100 operisanih bolesnika 46% su u grupi visokog rizika od kojih kod 54% nastaju
metastaze ili lokalni recidiv. Od ukupno 100 ispitivanih bolesnika, kod 45 bolesnika je dobijen mutacioni
status, gde su 37 (82%) bolesnika sa KIT mutacijama, 6 (14%) bolesnika sa PDGFRA mutacije i 2 (4%)
bolesnika svrstani u "wild type". Analizom krive preživljavanja kod bolesnika operisanih zbog GIST
želuca utvrđena je značajna razlika u javljanju metastaze i smrtnog ishoda u zavisnosti od tipa
mutacije(p=0.023). Cox-ovim regresionom analizom je pokazano da bolesnici visokog rizika sa
recidivom bolesti koji nisu primali Imatinib imali su 7 puta veću verovatnoću smrtnog ishoda u odnosu na
bolesnike lečene Imatinobom
Zaključak: Analiza mutacije na KIT i PDGFRA genima ima prognostički i prediktivni značaj kod
bolesnika operisanih zbog GIST želuca. Imatinib ima značajnu ulogu u lečenju bolesnika koji su u grupi
viskog rizika.Objective: KIT (KIT proto-oncogene receptor tyrosine kinase) and PDGFRA (Platelet derived growth
factor receptor alpha) gene mutations represent major molecular forces inside the gastrointestinal stromal
tumors (GIST). Aim of this study was to evaluate these mutations in patients who underwent surgical
resection of gastric GIST
Methods: Retrospective clinical study included 100 patients who were operated due to gastric GIST from
2005 till 2016. Molecular analysis of paraffin embedded tumor tissue was performed, and the 45 patients
who had presence of KIT and PDGFRA mutations were further evaluated, with regard to pathological
tumor stage, disease recurrence and overall survival.
Results: Of the 100 patients who were operated 46% are in the high risk group of which at 54% of the
resulting metastasis or local recurrence. From a total of 100 patients, in 45 patients we obtained
mutational status, where 37 (82%) of patients had KIT mutations, 6 (14%) patients had PDGFRA
mutations and 2 (4%) patients were classified into the “ wild-type”. The analysis of survival curves in
patients surgically treated for gastric GIST showed a significant difference in emergence of metastases
and death depending on the type of mutation (p = 0.023). Cox's regression analysis shown that patients
with a high risk of recurrent disease who were not receiving Imatinib had the 7 times greater probability
of fatal outcome compared to patients treated with Imatinib.
Conclusion: Analysis of mutations in the genes KIT and PDGFRA has prognostic and predictive
significance in patients surgically treated for gastric GIST. Imatinib has an important role in the treatment
of patients who are in the group of high risk
Significance of KIT and PDGFRA gene mutation in evaluation of surgically treated gastric gastrointestinal stromal tumor patients
No full textCilj: Ispitivanje genetskih mutacija na KIT i PDGFRA genima, prikazivanje njihove učestalosti, vrste
mutacija i korelacije ovih specifičnih genskih mutacija sa patohistološkim i imunohistohemijskim
karakteristikama tumora. Korelacija genetskih mutacija na KIT i PDGFRA sa kliničkim tokom operisanih
bolesnika.
Metod: Prospektivna i delimično retrospektivna klinička studija koja je uključila 100 bolesnika operisane
zbog GIST-a želuca u period od 2005 do 2016 godine. Načinjena je molekularna analiza na parafinskim
kalupima tumorskog tkiva, a kod 45 bolesnika kod kojih su identifikovane KIT i PDGFRA mutacije
sprovedena je dalja analiza, sa posebnim osvrtom na patološke karakteristike tumora, recidiv oboljenja i
ukupno preživljavanje, te procena uticaja analiziranih genskih mutacija na navedene promene.
Rezultati: Od 100 operisanih bolesnika 46% su u grupi visokog rizika od kojih kod 54% nastaju
metastaze ili lokalni recidiv. Od ukupno 100 ispitivanih bolesnika, kod 45 bolesnika je dobijen mutacioni
status, gde su 37 (82%) bolesnika sa KIT mutacijama, 6 (14%) bolesnika sa PDGFRA mutacije i 2 (4%)
bolesnika svrstani u "wild type". Analizom krive preživljavanja kod bolesnika operisanih zbog GIST
želuca utvrđena je značajna razlika u javljanju metastaze i smrtnog ishoda u zavisnosti od tipa
mutacije(p=0.023). Cox-ovim regresionom analizom je pokazano da bolesnici visokog rizika sa
recidivom bolesti koji nisu primali Imatinib imali su 7 puta veću verovatnoću smrtnog ishoda u odnosu na
bolesnike lečene Imatinobom
Zaključak: Analiza mutacije na KIT i PDGFRA genima ima prognostički i prediktivni značaj kod
bolesnika operisanih zbog GIST želuca. Imatinib ima značajnu ulogu u lečenju bolesnika koji su u grupi
viskog rizika.Objective: KIT (KIT proto-oncogene receptor tyrosine kinase) and PDGFRA (Platelet derived growth
factor receptor alpha) gene mutations represent major molecular forces inside the gastrointestinal stromal
tumors (GIST). Aim of this study was to evaluate these mutations in patients who underwent surgical
resection of gastric GIST
Methods: Retrospective clinical study included 100 patients who were operated due to gastric GIST from
2005 till 2016. Molecular analysis of paraffin embedded tumor tissue was performed, and the 45 patients
who had presence of KIT and PDGFRA mutations were further evaluated, with regard to pathological
tumor stage, disease recurrence and overall survival.
Results: Of the 100 patients who were operated 46% are in the high risk group of which at 54% of the
resulting metastasis or local recurrence. From a total of 100 patients, in 45 patients we obtained
mutational status, where 37 (82%) of patients had KIT mutations, 6 (14%) patients had PDGFRA
mutations and 2 (4%) patients were classified into the “ wild-type”. The analysis of survival curves in
patients surgically treated for gastric GIST showed a significant difference in emergence of metastases
and death depending on the type of mutation (p = 0.023). Cox's regression analysis shown that patients
with a high risk of recurrent disease who were not receiving Imatinib had the 7 times greater probability
of fatal outcome compared to patients treated with Imatinib.
Conclusion: Analysis of mutations in the genes KIT and PDGFRA has prognostic and predictive
significance in patients surgically treated for gastric GIST. Imatinib has an important role in the treatment
of patients who are in the group of high risk
Impact of surgical approach on treatment outcome in patients with esophageal and esophagogastric junction cancer
No full textHirurgija karcinoma jednjaka i ezofagogastričnog prelaza, kao jedna od najkompleksnijih oblasti digestivne hirurgije, je i dalje povezana sa visokim stopama morbiditeta i mortaliteta, uz relativno nisko ukupno preživljavanje. Uprkos velikom napretku poslednjih decenija, stope mortaliteta se u mnogim centrima širom sveta održavaju na vrednostima od 5-10%, a petogodišnje preživljavanje radikalno operisanih pacijenata retko kada prelazi stopu od 25-30%. Iako je velikim delom ova hirurgija standardizovana, neka pitanja i dalje ostaju otvorena. Definisanjem ciljeva naše studije smo se fokusirali na postojeće kontroverze, i time pokušali da damo skromni doprinos u iznalaženju optimalnih modaliteta lečenja ovih pacijenata. Naša studija je po dizajnu retrospektivna kohortna studija, koja je obuhvatila dvanaestogodišnji period od 01.01.2004.-01.01.2016 godine. U navedenom periodu je u Centru za hirurgiju jednjaka operisano 1129 pacijenata zbog karcinoma jednjaka i želuca. U studiju smo uključili radikalno operisane pacijente sa karcinomom jednjaka i ezofagogastričnog prelaza, kojih je nakon definisanja kriterijuma bilo ukupno 529.
Osnovni ciljevi naše studije bili su: 1. utvđivanje kliničko-patološki karakteristika i perioperativnih rezultata lečenja (morbiditet i mortalitet), kao i analiza preživljavanja ove homogene populacije pacijenata; 2. Ispitivanje značaja Lymph Node Ratio (LNR) i njegovo poređenje sa N stadijumom prema 7. izdanju TNM klasifikacije; 3. Ispitivanje značaja hirurškog pristupa za ishod lečenja pacijenata sa karcinomomima ezofagogastričnog prelaza tipa II po Siewert-ovoj klasifikaciji; 4. Uticaj statusa cirkumferentne resekcione margine, definisane prema dva postojeća kriterijuma klasifikacije (Kraljevsko udruženje patologa i Američko udruženje patologa) na ukupno preživljavanje, pojavu recidiva i pojavu lokalnih recidiva bolesti; 5. Uticaj transfuzije alogene krvi na ishod lečenja operisanih pacijenata.
Karcinom jednjaka i ezofagogastričnog prelaza se najčešće javljao u sedmoj deceniji života (60±10.3), a dominirao je muški pol (4:1). Mediana dužine hospitalizacije je iznosila 15 dana (raspon:14.0-19.0 dana), a intrahospitalni mortalitet 2.8%...complex field in digestive surgery, is still burdened with high morbidity and mortality rates and relatively poor overall survival. Despite the great progress in the recent decades, a mortality rate remains high worldwide (5-10%), with 5-year survival rates that rarely exceeds 25-30% in the population of patients operated with radical intent. Althought mostly standardized, there are some dilemmas that remain unanswered. Aims of our study were focused on the existing controversies, trying to give a modest contribution in defining optimal treatment modalities for this patient population. Our study was designed as restrospective cohort study, with all limitations by the study design, which enrolled consecutive patients operated on esophageal and esophagogastric junction cancer in the period between January 2004 and January 2016. There were 1129 surgically treated patients due to esophageal and gastric cancer in the observed period. Finally, 529 patiens have met our criteria and were included in the analysis.
Aims of our study were: 1. To determine basic clinical and pathological characteristics, perioperative (morbidity and mortality) and long term outcome of the study population; 2. To investigate significance of LNR; 3. To compare two surgical approaches (esophagectomy versus extended total gastrectomy), and their impact on outcome of patients with Siewert type II esophagogastric junction cancer; 4. To compare two different classifications of CRM and their impact on surgical outcome; 5. To investigate impact of allogeneic blood transfusion following surgical treatment of esophageal and esophagogastric junction cancer.
Most of the patients in our study were in seventh decade of life (60±10.3), with male predominance (4:1). Median in-hospital stay was 15 days (range: 14.0-19.0), in-hospital mortality of 2.8%..
Impact of surgical approach on treatment outcome in patients with esophageal and esophagogastric junction cancer
No full textHirurgija karcinoma jednjaka i ezofagogastričnog prelaza, kao jedna od najkompleksnijih oblasti digestivne hirurgije, je i dalje povezana sa visokim stopama morbiditeta i mortaliteta, uz relativno nisko ukupno preživljavanje. Uprkos velikom napretku poslednjih decenija, stope mortaliteta se u mnogim centrima širom sveta održavaju na vrednostima od 5-10%, a petogodišnje preživljavanje radikalno operisanih pacijenata retko kada prelazi stopu od 25-30%. Iako je velikim delom ova hirurgija standardizovana, neka pitanja i dalje ostaju otvorena. Definisanjem ciljeva naše studije smo se fokusirali na postojeće kontroverze, i time pokušali da damo skromni doprinos u iznalaženju optimalnih modaliteta lečenja ovih pacijenata. Naša studija je po dizajnu retrospektivna kohortna studija, koja je obuhvatila dvanaestogodišnji period od 01.01.2004.-01.01.2016 godine. U navedenom periodu je u Centru za hirurgiju jednjaka operisano 1129 pacijenata zbog karcinoma jednjaka i želuca. U studiju smo uključili radikalno operisane pacijente sa karcinomom jednjaka i ezofagogastričnog prelaza, kojih je nakon definisanja kriterijuma bilo ukupno 529.
Osnovni ciljevi naše studije bili su: 1. utvđivanje kliničko-patološki karakteristika i perioperativnih rezultata lečenja (morbiditet i mortalitet), kao i analiza preživljavanja ove homogene populacije pacijenata; 2. Ispitivanje značaja Lymph Node Ratio (LNR) i njegovo poređenje sa N stadijumom prema 7. izdanju TNM klasifikacije; 3. Ispitivanje značaja hirurškog pristupa za ishod lečenja pacijenata sa karcinomomima ezofagogastričnog prelaza tipa II po Siewert-ovoj klasifikaciji; 4. Uticaj statusa cirkumferentne resekcione margine, definisane prema dva postojeća kriterijuma klasifikacije (Kraljevsko udruženje patologa i Američko udruženje patologa) na ukupno preživljavanje, pojavu recidiva i pojavu lokalnih recidiva bolesti; 5. Uticaj transfuzije alogene krvi na ishod lečenja operisanih pacijenata.
Karcinom jednjaka i ezofagogastričnog prelaza se najčešće javljao u sedmoj deceniji života (60±10.3), a dominirao je muški pol (4:1). Mediana dužine hospitalizacije je iznosila 15 dana (raspon:14.0-19.0 dana), a intrahospitalni mortalitet 2.8%...complex field in digestive surgery, is still burdened with high morbidity and mortality rates and relatively poor overall survival. Despite the great progress in the recent decades, a mortality rate remains high worldwide (5-10%), with 5-year survival rates that rarely exceeds 25-30% in the population of patients operated with radical intent. Althought mostly standardized, there are some dilemmas that remain unanswered. Aims of our study were focused on the existing controversies, trying to give a modest contribution in defining optimal treatment modalities for this patient population. Our study was designed as restrospective cohort study, with all limitations by the study design, which enrolled consecutive patients operated on esophageal and esophagogastric junction cancer in the period between January 2004 and January 2016. There were 1129 surgically treated patients due to esophageal and gastric cancer in the observed period. Finally, 529 patiens have met our criteria and were included in the analysis.
Aims of our study were: 1. To determine basic clinical and pathological characteristics, perioperative (morbidity and mortality) and long term outcome of the study population; 2. To investigate significance of LNR; 3. To compare two surgical approaches (esophagectomy versus extended total gastrectomy), and their impact on outcome of patients with Siewert type II esophagogastric junction cancer; 4. To compare two different classifications of CRM and their impact on surgical outcome; 5. To investigate impact of allogeneic blood transfusion following surgical treatment of esophageal and esophagogastric junction cancer.
Most of the patients in our study were in seventh decade of life (60±10.3), with male predominance (4:1). Median in-hospital stay was 15 days (range: 14.0-19.0), in-hospital mortality of 2.8%..
The role of emotions in process of interpretation Literary Work by Guided Reading
No full textSvrha i cilj ovoga rada spajanje je teorijske spoznaje s rezultatima znanstvenih istraživanja kako bi se kreirali i ponudili modeli strukturiranih programa poticanja čitanja vođenim čitanjem u narodnim knjižnicama. Narodnu knjižnicu nastoji se situirati kao „prirodno mjesto“ za provođenje posebnih programa poticanja čitanja (kao svoju redovnu uslugu), koji psihološki, kognitivno, socijalno i kulturološki utječu na čitanje/čitatelja, na razvoj promicanja i poticanja čitanja vođenim čitanjem. Provedena su dva istraživanja – područje vrjednovanja posebnih programa poticanja čitanja u narodnim knjižnicama i eksperimentalno istraživanje učinka posebnih programa poticanja čitanja vođenim čitanjem na korisnike (odabrane fokus grupe) i knjižničara kao voditelja takvih programa. Zajedničko im je da narodnu knjižnicu odrede kao „prirodno mjesto“ za komunikacijski krug autor – djelo – knjižničar – čitatelj. Anketnim upitnicima istraživalo se i vrjednovalo kako se narodna knjižnica svojom novom korisničkom ponudom, programima poticanja čitanja, prilagođava promjenama u pristupu korisniku (individualno) i suvremenim socio-psihološkim kretanjima društva u cjelini.
Na temelju eksperimentalnih istraživanja potvrđeni su očekivani rezultati – učinci o djelotvornosti provođenja programa vođenoga čitanja kao i očekivanje jačanja čitateljskoga samopouzdanja. Sudionici programa vođenoga čitanja (fokus grupe) pozitivno su evaluirali radionice na skali od 1 do 10 evaluacijskoga listića visokim ocjenama između 6 i 10.Purpose and objective of this paper is to interconnect theoretical knowledge with the results of scientific research with the main goal of creating
and offering models of structured reading promotion programmes by guided reading in public libraries. Public library has to be positioned as
a “natural place” for conducting special reading promotion programmes (as a regular service) which psychologically, cognitively, socially and culturologically affect reading/the reader, as well as development of reading promotion by guided reading. This paper contains two researches – field of evaluation of special reading promotion programmes in public libraries and experimental research of impact of special reading promotion programmes
by guided reading on users (chosen focus groups) and a librarian as a programme leader. They have in common the appointment of a public
library as a “natural place” for the communication circle author – work – librarian – reader. Questionnaires were used to research and evaluate how
a public library with its new users offer, reading promotion programmes, adapts to changes in users approach (individually) and contemporary
sociopsychological tendencies in the society as such. Based on experimental researches expected results were confirmed – impact on efficacy
of conducting guided reading programmes as well as strengthening reading self-confidence. Participants in guided reading programmes (focus
groups) positively evaluated guided reading workshops on an evaluation form scale from 1 to 10 with high grades 6 and 1
The Works of Dr. Seuss in Bibliotherapy
No full textTeachers have a growing responsibility in guiding students in their character development and in helping them develop necessary skills to face current and future obstacles. While bibliotherapy is still a developing method, present in many fields and modes of application, the therapeutic effect of books is becoming increasingly apparent among the populace. Although bibliotherapy is still not commonly used by teachers in classrooms, as many still lack the guidance and knowledge about the process, developmental bibliotherapy is an approach to ensure normal development and a means of educating children about affective aspects such as feelings and behaviour. Dr. Seuss, as an esteemed children’s author, is already present in many classrooms and his works offer much more than literacy education. They guide the reader, in this case the students, in developing positive thinking patterns, awareness of self and others, as well as reinforce the importance of critical thinking and developing problem solving strategies. As a proponent of positive psychology, Seuss’ works can serve as a gateway to bibliotherapy in the classroom. The aim of this thesis is to further examine the possibility and plausibility of the implementation of the works of Dr. Seuss in a bibliotherapy lesson in the classroom. Through the analysis of one of Seuss’s better known picturebooks Oh, the Places You’ll Go further insight is given to the complexity of the seemingly simple works of Dr. Seuss and the potential of use in developmental bibliotherapy. The aforementioned title is used as a base for the development of a potential bibliotherapy lesson and accompanying activities.Nastavnici imaju sve veću odgovornost u vođenju učenika u razvoju njihova karaktera i vještina potrebnih za suočavanje s trenutnim i budućim problemima. Dok je biblioterapija metoda koja se još uvijek razvija, i kao takva je prisutna u mnogim područjima s različitom primjenom, terapeutski učinak knjiga postaje sve očitiji u široj primjeni. Iako se biblioterapija još uvijek ne koristi u svim učionicama, budući da mnogim učiteljima još uvijek nedostaju smjernice i znanja o tome procesu, razvojna biblioterapija je tehnika koja može omogućiti i upotpuniti normalan razvoj djeteta i njegovo stjecanje znanja o afektivnim aspektima ličnosti kao što su osjećaji i različita ponašanja. Dr. Seuss, kao cijenjeni dječji autor, već je prisutan u mnogim učionicama, a njegova djela nude mnogo više od književnog predloška za učenje čitanja. Njegova djela usmjeravaju čitatelja, u ovom slučaju učenike, u razvijanju pozitivnih obrazaca razmišljanja, svijesti o sebi i drugima, kao i jačanju važnosti kritičkog razmišljanja i razvijanju strategija rješavanja problema. Kao zagovornik pozitivne psihologije, Seuss i njegova djela mogu poslužiti kao biblioterapijski materijal u učionici. Cilj ovog rada je ispitati mogućnost i smislenost uvođenja radova Dr. Seussa u izvedbi biblioterapije u učionici. Analizom jednog od Seussovih poznatijih slikovnica Oh, the Places You’ll Go dat će se uvid u složenost naizgled jednostavnih djela Dr. Seussa i potencijal korištenja inih u razvojnoj biblioterapiji. Navedeni naslov koristi se kao osnova za razvitak potencijalnog biblioterapijskog sata i pratećih aktivnosti
