31 research outputs found

    Acrokeratosis paraneoplastica Bazex syndrome associated with esophageal squamocellular carcinoma

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    Background. Acrokeratosis paraneoplastica Bazex (APB) is a very rare disease in the group of obligate paraneoplastic dermatoses, associated mostly with squamous cell carcinoma of the upper aerodigestive tract and metastatic cervical lymphadenopathy. The disease is characterized by violaceous erythemosquamous changes on the acral regions. This entity was first reported by Bazex in 1965. About 160 cases have been presented so far. Case report. We presented a patient with a three-month history of violaceous erythema, edema, erosions and scaling on the acral regions, elbows and knees and severe nail dystrophy. When the diagnosis was established, he did not have any symptom of internal malignancy. Esophagogastroscopy revealed ulcerovegetant lesion of the esophagus, while histology showed squamocellular invasive carcinoma. Surgical tumor removal resulted in significant improvement of skin changes in 15 days. Unfortunately, four months later, extensive skin lesions pointed to metastasis of squamous cell carcinoma. Conclusion. Skin changes can precede a few years the first manifestations of neoplasia. The course of the disease in our patient proved that APB is a specific marker of underlying malignancy.</jats:p

    Rendgenska palijacija disfagije - plasiranje ezofagealnog stenta pod kontrolom rendgenoskopije

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    As for the gastrointestinal tract, stents are most commonly applied in the esophagus. Majority of the esophageal stents are implanted for the purpose of palliation of the inoperable malignant dysphagias, however they may also be used, although less frequently, for dilatation of the constricted anastomosis, covering of fistulas and least frequently for dilatation of the benign stenoses. Increasingly frequently the stents are used in the prepyloric gastric region, duodenal and rectosigmoid portion of the colon. The paper describes our own six-year experience in application of the gastrointestinal stents for palliation of dysphagia.</jats:p
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