572 research outputs found

    sj-docx-1-hol-10.1177_09596836231183110 – Supplemental material for Holocene precipitation hydrogen isotopic values on Nilgiri Plateau (southern India) suggest a combined effect of precipitation amount and transport paths

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    Supplemental material, sj-docx-1-hol-10.1177_09596836231183110 for Holocene precipitation hydrogen isotopic values on Nilgiri Plateau (southern India) suggest a combined effect of precipitation amount and transport paths by Shreyas Managave, Yongsong Huang, Jean-Pierre Sutra, Krishnamurthy Anupama and Srinivasan Prasad in The Holocene</p

    GPU-accelerated depth map generation for X-ray simulations of complex CAD geometries

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    Interactive x-ray simulations of complex computer-aided design (CAD) models can provide valuable insights for better interpretation of the defect signatures such as porosity from x-ray CT images. Generating the depth map along a particular direction for the given CAD geometry is the most compute-intensive step in x-ray simulations. We have developed a GPU-accelerated method for real-time generation of depth maps of complex CAD geometries. We preprocess complex components designed using commercial CAD systems using a custom CAD module and convert them into a fine user-defined surface tessellation. Our CAD module can be used by different simulators as well as handle complex geometries, including those that arise from complex castings and composite structures. We then make use of a parallel algorithm that runs on a graphics processing unit (GPU) to convert the finely-tessellated CAD model to a voxelized representation. The voxelized representation can enable heterogeneous modeling of the volume enclosed by the CAD model by assigning heterogeneous material properties in specific regions. The depth maps are generated from this voxelized representation with the help of a GPU-accelerated ray-casting algorithm. The GPU-accelerated ray-casting method enables interactive (> 60 frames-per-second) generation of the depth maps of complex CAD geometries. This enables arbitrarily rotation and slicing of the CAD model, leading to better interpretation of the x-ray images by the user. In addition, the depth maps can be used to aid directly in CT reconstruction algorithms.This proceeding may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This proceeding appeared in Grandin, Robert J., Gavin Young, Stephen D. Holland, and Adarsh Krishnamurthy. "GPU-accelerated depth map generation for X-ray simulations of complex CAD geometries." In AIP Conference Proceedings, vol. 1949, no. 1, p. 190002. AIP Publishing LLC, 2018, and may be found at DOI: 10.1063/1.5031636. Copyright 2018 Author(s). Posted with permission

    NURBS-Diff: A Differentiable Programming Module for NURBS

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    Boundary representations (B-reps) using Non-Uniform Rational B-splines (NURBS) are the de facto standard used in CAD, but their utility in deep learning-based approaches is not well researched. We propose a differentiable NURBS module to integrate NURBS representations of CAD models with deep learning methods. We mathematically define the derivatives of the NURBS curves or surfaces with respect to the input parameters (control points, weights, and the knot vector). These derivatives are used to define an approximate Jacobian used for performing the “backward” evaluation to train the deep learning models. We have implemented our NURBS module using GPU-accelerated algorithms and integrated it with PyTorch, a popular deep learning framework. We demonstrate the efficacy of our NURBS module in performing CAD operations such as curve or surface fitting and surface offsetting. Further, we show its utility in deep learning for unsupervised point cloud reconstruction and enforce analysis constraints. These examples show that our module performs better for certain deep learning frameworks and can be directly integrated with any deep-learning framework requiring NURBS.This is a manuscript of the article published as Prasad, Anjana Deva, Aditya Balu, Harshil Shah, Soumik Sarkar, Chinmay Hegde, and Adarsh Krishnamurthy. "NURBS-diff: A differentiable programming module for NURBS." Computer-Aided Design 146 (2022): 103199. doi: https://doi.org/10.1016/j.cad.2022.103199

    Incorporation of composite defects from ultrasonic NDE into CAD and FE models

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    Fiber-reinforced composites are widely used in aerospace industry due to their combined properties of high strength and low weight. However, owing to their complex structure, it is difficult to assess the impact of manufacturing defects and service damage on their residual life. While, ultrasonic testing (UT) is the preferred NDE method to identify the presence of defects in composites, there are no reasonable ways to model the damage and evaluate the structural integrity of composites. We have developed an automated framework to incorporate flaws and known composite damage automatically into a finite element analysis (FEA) model of composites, ultimately aiding in accessing the residual life of composites and make informed decisions regarding repairs. The framework can be used to generate a layer-by-layer 3D structural CAD model of the composite laminates replicating their manufacturing process. Outlines of structural defects, such as delaminations, are automatically detected from UT of the laminate and are incorporated into the CAD model between the appropriate layers. In addition, the framework allows for direct structural analysis of the resulting 3D CAD models with defects by automatically applying the appropriate boundary conditions. In this paper, we show a working proof-of-concept for the composite model builder with capabilities of incorporating delaminations between laminate layers and automatically preparing the CAD model for structural analysis using a FEA software.This proceeding may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This proceeding appeared in Bingol, Onur Rauf, Bryan Schiefelbein, Robert J. Grandin, Stephen D. Holland, and Adarsh Krishnamurthy. "Incorporation of composite defects from ultrasonic NDE into CAD and FE models." AIP Conference Proceedings 1806, no. 1, (2017): 150004. , and may be found at DOI: 10.1063/1.4974728. Posted with permission.</p

    Differentiable Spline Approximations

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    The paradigm of differentiable programming has significantly enhanced the scope of machine learning via the judicious use of gradient-based optimization. However, standard differentiable programming methods (such as autodiff) typically require that the machine learning models be differentiable, limiting their applicability. Our goal in this paper is to use a new, principled approach to extend gradient-based optimization to functions well modeled by splines, which encompass a large family of piecewise polynomial models. We derive the form of the (weak) Jacobian of such functions and show that it exhibits a block-sparse structure that can be computed implicitly and efficiently. Overall, we show that leveraging this redesigned Jacobian in the form of a differentiable "layer" in predictive models leads to improved performance in diverse applications such as image segmentation, 3D point cloud reconstruction, and finite element analysis.This is a proceeding preprint from Cho, Minsu, Aditya Balu, Ameya Joshi, Anjana Deva Prasad, Biswajit Khara, Soumik Sarkar, Baskar Ganapathysubramanian, Adarsh Krishnamurthy, and Chinmay Hegde. "DIFFERENTIABLE SPLINE APPROXIMATIONS." arXiv preprint arXiv:2110.01532 (2021). doi: https://doi.org/10.48550/arXiv.2110.01532. Copyright 2021 The Authors

    Optogenetic control of developmental signaling pathways

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    How a complex multicellular organism forms from a single cell is a question that defies simplistic understanding. Yet, embryonic developmental programs use a surprisingly small set of signaling pathways to pattern the embryonic tissue into germ layers from which the various tissues and organs emerge. A hallmark of embryonic development is that these recurring developmental signaling pathways are carefully orchestrated in space and time to facilitate proper development. Understanding the spatiotemporal intricacies of these pathways necessitates tools which enable their perturbation in precisely defined spatiotemporal patterns. Optogenetics uses light-induced conformational changes to enable or disable protein-protein interactions, thereby permitting control of signal transduction at the flip of a switch. Consequently, light is emerging as a powerful tool to study embryonic development owing to its rapid, reversible and residue-free application, which empowers the researcher with excellent spatial and temporal control of signaling. Here, I first review recent accomplishments in optical microscopy and optogenetics which highlight the dual roles of light in visualizing as well as perturbing cellular microenvironments and processes. Second, I present an optogenetic approach to control the mitogen-activated protein kinase (MAPK) pathway which we successfully applied in both neuroblasts and frog embryos. Third, I demonstrate an optogenetic approach to control the Wnt signaling pathway in mammalian cells and frog embryos. Finally, I propose and provide working proof for a generalizable optogenetic platform to control those developmental signaling pathways, the activities of which involve the homo-association of plasma membrane-localized receptor tyrosine kinases.Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2021-12-01The student, Vishnu Vardhan Krishnamurthy, accepted the attached license on 2019-11-27 at 10:27.The student, Vishnu Vardhan Krishnamurthy, submitted this Dissertation for approval on 2019-11-27 at 10:29.This Dissertation was approved for publication on 2019-12-04 at 10:19.DSpace SAF Submission Ingestion Package generated from Vireo submission #14554 on 2020-02-28 at 17:36:14Made available in DSpace on 2020-03-02T22:38:43Z (GMT). No. of bitstreams: 3 KRISHNAMURTHY-DISSERTATION-2019.pdf: 4133154 bytes, checksum: 8f070afeeb5cd05e2c8ff2a6e6a2d565 (MD5) Dev- license.pdf: 2415159 bytes, checksum: a102a998392b7fbc917eae1a15da3e07 (MD5) LICENSE.txt: 4225 bytes, checksum: 1be243ed801709bdfa611fbfaeb309b4 (MD5) Previous issue date: 2019-12-04Embargo set by: Seth Robbins for item 113989 Lift date: 2022-03-02T22:39:04Z Reason: Author requested closed access (OA after 2yrs) in Vireo ETD systemLimited Restriction Lifted for Item 113989 on 2022-03-03T10:15:19Z
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