509 research outputs found
The Neighbourhood of Infinity
No full textFanzine dedicated to the work of Mark E Smith and The Fall. Collaboration between myself and artists, Inge Marleen and David Powell. Sole author of text:
“And then I heard a voice say, ‘Hey, you’re lost in music.’
If #MeToo Came True: Author Marleen Barr and K-B Have a Chat
No full textThis is an interview with Marleen S. Barr which refers to her short fiction collection When Trump Changed: The Feminist Science Fiction Justice league Quashes the Orange Outrage Pussy Grabber
Marleen and Vickie Webb
No full textThis 1964 photograph shows Marleen and Vickie Webb, also known as the Waynesville Cousins singing. Founder and director of the Mountain Youth Jamboree, Hubert H. Hayes (1901-1964) auditioned and directed youth to perform in folk dance, music, and folk and ballad singing. The jamboree was held in the Asheville City Auditorium (now known as Thomas Wolfe Auditorium) from 1948 to 1973, and Hayes’ wife, Leona Trantham Hayes (1913-1989) continued to direct the program after his death in 1964. Hubert Hayes was an author, playwright, and alumni of Duke University
Feminist Sci-Fi Author Pens Fantasy Short Story Collection About Trump Post-Impeachment, In A Galaxy Far Far Away
No full textThis blog post contains a short story published in Marleen S. Barr\u27s WHEN TRUMP CHANGED: THE FEMINIST SCIENCE FICTION JUSTICE LEAGUE QUASHES THE ORANGE OUTRAGE PUSSY GRABBER
ABO-mismatch adult living donor liver transplantation using antigen-specific immunoadsorption and quadruple immunosuppression without splenectomy
No full textABO-incompatible (ABO-I) liver transplantation is a controversial issue because of the generally less favorable outcome as compared to compatible transplants. Encouraging results have been shown by the introduction of new strategies to reduce posttransplant-specific hemagglutinin (HA) titers with plasmapheresis, reinforced immunosuppression (IS), and the use of splenectomy. We describe a new protocol consisting of daclizumab (DAC) induction, mycophenolate mofetil (MMF)/tacrolimus (TAC)/steroids without splenectomy. Five recipients (mean age of 47 +/- 14 yr) undergoing ABO-I living donor liver transplantation (LDLT) were included in this protocol. Immunoadsorbent columns (Glycosorb ABO) were used for antigen-specific immunoadsorption (ASI). The median follow-up was 18.5 +/- 10.5 months. ASI was very efficient in lowering HA titers (mean log, immunoglobulin [Ig] M [IgM] and IgG values before and after ASI were 5.9 +/- 2.8 and 1.2 +/- 1.4 [P = 0.0038] and 6.5 +/- 2.3 and 1.1 +/- 1.9, respectively [P = 0.0001]). Persisting low HA titers were observed over time. No sepsis nor cytomegalovirus infection episodes were recorded. Acute cellular rejection (ACR) occurred in 1 recipient responding to steroid pulse therapy. Two grafts were lost in 2 patients due to technical failure during the first postoperative month. We conclude that ASI using Glycosorb ABO, quadruple immunosuppression including DAC and MMF provide high efficiency to lower HA titers over time, avoiding the need for splenectomy. ABO-I LDLT can be performed with this adapted IS protocol
Multiparametric magnetic resonance imaging characteristics of normal, benign and malignant conditions in the prostate
No full textObjectives: To identify the multiparametric magnetic resonance imaging (mpMRI) characteristics of normal, benign and malignant conditions in the prostate.
Methods: Fifty-six histopathological whole-mount radical prostatectomy specimens from ten randomly selected patients with prostate cancer (PC) were matched with corresponding transverse mpMRI slices. The mpMRI was performed prior to biopsy and consisted of T2-weighted imaging (T2-WI), diffusion-weighted imaging (DWI), dynamic contrastenhanced imaging (DCE) and magnetic resonance spectroscopic imaging (MRSI).
Results: In each prostate specimen, a wide range of histopathological conditions were observed. They showed consistent but overlapping characteristics on mpMRI. Normal glands in the transition zone showed lower signal intensity (SI) on T2-WI, lower ADC values and lower citrate peaks on MRSI as compared to the peripheral zone (PZ) due to sparser glandular elements and more prominent collagenous fibres. In the PZ, normal glands were iso-intense on T2-WI, while high SI areas represented cystic atrophy. Mimickers of well-differentiated PC on mpMRI were inflammation, adenosis, HG-PIN and post-atrophic hyperplasia.
Conclusion: Each prostate is a unique mix of normal, benign and/or malignant areas that vary in extent and distribution resulting in very heterogeneous characteristics on mpMRI. Understanding the main concepts of this mpMRIhistopathological correlation may increase the diagnostic confidence in reporting mpMRI
A case of HPV-53-related cervical cancer in an elderly patient
No full textMarusya Lieveld,1 Elizaveta Padalko,2,3 Marleen Praet,4 Davy Vanden Broeck1 1Department of Uro/gynaecology, Ghent University Hospital, Ghent, Belgium; 2Department of Clinical Chemistry, Microbiology and Immunology, Ghent University Hospital, Ghent, Belgium; 3School of Life Sciences, Hasselt University, Diepenbeek, Belgium; 4N. Goormaghtigh Institute of Pathology, Ghent University Hospital, Ghent, BelgiumZappacosta et al1 recently published a case report concerning a human papillomavirus (HPV)-positive invasive cervical cancer in a 79-year-old women who had a history of normal Pap smears. In this article, Anyplex II HPV28 (Seegene) is used for HPV genotyping of formalin-fixed paraffin embedded (FFPE) tissue, liquid based cytology (LBC) specimens and urine samples. It is suggested that HPV53 is present exclusively in the cervical cancer cells, lymph node metastases, and atypical urinary cells of one single case while the surrounding CIN2+ tissue revealed ten different HPV strains. Unfortunately, the HPV genotype results for lymph nodes and urinary cells are not presented while these results underline the potential role of HPV53 in oncogenesis. Moreover, it is generally accepted that one lesion is caused by one HPV infection, detection of multiple HPV types thus indicates the presence of multiple infections,2 suggesting that this patient may have several lesions. Read the original article  
Cancer of the uterine cervix among women of Kinshasa, the Democratic Republic of the Congo : prevalence, co-factors and the human papillomavirus
No full textVerbs of pain and accusative subjects in Romanian
No full textVerbs of pain in Romanian such as durea ‘ache’, ustura ‘burn’, and furnica ‘itch’ assign the accusative to their experiencer arguments, unlike other Romance languages, where the experiencer is dative-marked. The use of the accusative raises interesting problems in that it gives rise to a mismatch between the hypothesis on the syntax of inalienability in Romance in Generative Grammar (Guéron 1985) and Burzio’s (1986) Generalization. This article shows that the inversed nominative NP denoting the body part does not show subject properties, and that the accusative experiencer in sentence initial position does not show object properties, but instead displays subject properties, just like the dative in similar constructions. However, the difference between accusative and dative subjects in this construction is that the accusative is assigned to verb arguments and is a lexical case, whereas the dative is assigned to external possessors and is an inherent case. Surprisingly, the argument status of the accusative experiencer makes it even more subject-like than the dative experiencer, which is an adjunct and is dependent on the presence of an internal argument triggering verb agreement, whereas the accusative subject can also occur without an internal argument or with a locative PP
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