5,357 research outputs found
Author Peter FitzSimons speaking at the National Library of Australia, Canberra, 13 November 2012 /
Title from acquisitions documentation.; Part of the collection: Portraits of author Peter FitzSimons speaking at the National Library of Australia, Canberra, 13 November 2012.; Acquired in digital format; access copy available online.; Mode of access: Online.; Photographed by a staff member of the National Library of Australia
Dr. Craig Kinsley – Faculty Author Interview
Dr. Craig Kinsley, Professor of Psychology and co-author of Clinical Neuroscience, discusses this unique textbook that integrates neurobiological mechanisms of general health into the coverage of mental disorders. By using this resource, instructors can easily integrate principles of neuroscience into clinical, developmental, behavioral, cognitive, and social psychology. The second edition of Clinical Neuroscience will be published in early 2010
Professor Peter Singer speaking at the National Press Club Canberra, 11 February 2009 [picture] /
Title devised by cataloguer based on information from acquisitions documentation.; Part of the collection: Humanitarian author Professor Peter Singer at the National Press Club, Canberra, 11 February 2009.; Acquired in digital format; access copy available online.; Mode of access: Internet via World Wide Web.; Photographed by a staff member of the National Library of Australia, 2009
Computational modelling of cyclic peptides incorporating reverse turn peptidomimetics
As part of an effort to develop a model system for peptide recognition by proteins, two monoclonal antibodies (DB19/1 and DB19/25) were raised which recognised the pentapeptide Ac.PYPYDV which had been observed to adopt a type II turn in aqueous solution. As beta turns are commonly found in biologically active peptides and have been postulated to be the recognition element of several linear peptides, there has been considerable interest in the development of peptidomimetic analogues which stabilise beta turn conformation. Although such peptide analogues may exhibit increased potency and selectivity in their biological properties, any failure of the analogue to bind to its receptor may be due to the inability of the binding site to accommodate chemical modification of the peptide ligand rather than the analogue mimicking an inactive conformation.Our strategy in the elucidation of the bound conformation of Ac.YPYDV was to form a cyclic peptide incorporating the YPYD epitope. In this case, the cyclisation of the YPYD sequence to a rigid template was proposed. The chimeric analogue so formed would limit the conformation of the attached loop by fixing the geometry of the ends of the YPYD loop. It was noted that the use of a beta turn mimetic as the template group should induce a complementary beta turn across the tetrapeptide sequence. In contrast to traditional structure-function studies employing conformationally well-defined amino acid analogues such an "external" restraint would not affect the chemical structure of the peptide.In this case molecular modelling techniques were employed in the prediction of conformation as a preliminary study prior to any synthesis of chimeric mimetics. We therefore undertook an investigation of the conformation of the unconstrained peptides by the molecular modelling of the peptides using a Monte Carlo (MC) conformational search procedure. In order to effectively model this system a working understanding of the factors underlying adoption of secondary structure in solution as related to the sequence of peptide was required. Consequently, a limited nuclear magnetic resonance (NMR) analysis of the conformation of peptides related to the pentapeptide Ac.YPYDV was carried out. The computational results were then evaluated and interpreted on the basis of experimental NMR measurements.</p
The cultivation of (difficult) surfaces or “I know that’s a tree”
To coincide with the exhibition Real Painting at the Castlefield Gallery in Manchester Craig Staff, author of After Modernist Painting: The History of a Contemporary Practice (2013), offered his response to the exhibition, considering it in relation to painting’s histories, theories and philosophies. From connections with the Renaissance and modernism, he will venture towards the means by which we might begin to think about, if not understand the works that make up Real Painting
Bringing Hidden Organizations Out of the Shadows: Introduction to the Special Issue
This introduction to the special issue describes hidden organizations, offers several reasons for the lack of research on these collectives, and explains how this collection of articles helps move us forward in efforts to empirically study hidden organizations. After providing background information on the history of this special issue, the five articles published here are described in terms of the type of collective examined, the theories and methods used, and the key research questions addressed. Three observations about the published pieces are made: being hidden requires communicative effort; hiddenness is usefully understood in terms of identity management; and any discussion of hidden organizations raises ethical considerations. The piece closes with acknowledgements and a call for continued conceptual/theoretical and empirical research into hidden organizations.This is an introduction to a special issue on Hidden Organizations edited by the author. Published online before print: July 19, 2015
No.478 Craig Denton
Transcript (36 pages) of interview(s) by Rob DeBirk with Craig Denton on March 28, 2008Denton grew up on the east side of Salt Lake City. He attended Highland High School. A non-Mormon, he had the perspective of being on the outside looking in. Topics discussed include empty spaces like vacant lots that have since been filled in, the concept of wilderness, proposed wilderness areas of Utah\u27s West Desert, the Las Vegas water grab, his love of fishing and the Bear River, his career at the University of Utah, and the fight against the MX missile. Denton also talks about literature that influenced his thinking, including the works of Thoreau, Emerson, Walt Whitman and Rachel Carson. He also talks about the photography of Ansel Adams, Eliot Porter and Philip Hyde. Interview is part of the Utah Environmentalists Oral History Project. Interviewer: Rob DeBir
First person - Craig Keenan
ABSTRACT
First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping early-career researchers promote themselves alongside their papers. Craig Keenan is first author on ‘Post-traumatic osteoarthritis development is not modified by postnatal chondrocyte deletion of Ccn2’, published in DMM. Craig conducted the research described in this article while a postdoctoral research associate in Dr Blandine Poulet's lab at the University of Liverpool, Liverpool, UK. He is now a lecturer in vertebrate physiology in the lab of Dr Jason Kirby at Liverpool John Moores University, Liverpool, UK, investigating the roles of cartilage and bone in the pathogenesis of degenerative joint disease.</jats:p
Lee Durkee in Conversation with Tin House Publisher Craig Popelars
In this session, hosted by Square Books, Lee Durkee, author of The Last Taxi Driver, talks about writing, driving a cab, UFOs, Bigfoot, and Shakespeare with Tin House publisher Craig Popelars
Whittier House donor letter and list from Frederick P. Craig
Whittier House scrapbooks document Whittier House programs, events, and anniversary celebrations through newspaper clippings, lecture fliers, newsletters, event programs, and ticket stubs. Newspaper clippings are primarily from the Jersey Journal. There is also Whittier House fundraising materials, including pamphlets, appeal letters, brochures, and postcards. The Whittier House Social Settlement, the first settlement house in New Jersey, was established in Jersey City, N.J. (Hudson County) in 1894. Founded by Cornelia Foster Bradford, who would remain with the organization as headworker until 1926, Whittier House was based on the settlement house, Toynbee Hall, in England. Whittier House provided various recreational and educational programs, along with much needed social services, for the immigrant populations of Jersey City. Many of these successful services were used as models for large-scale social reform movements through the state. In 1935, the Whittier House was taken over by the Boys' Club of Jersey City
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