5,078 research outputs found
L-R: Katie Lee; Leo Walters; Bruce Berger sitting on a boat on the Colorado River.
Photo of Photo of Arizona folk singer and author Katie Lee (far left), Leo Walters (center), and writer Bruce Berger (far right), sitting on a raft on the Colorado River, Glen Canyon, Uta
ANZAC Day with Bruce Scates
This ANZAC Day will be unlike any other in living memory. But wherever we are, we can still come together and reflect. Come together this ANZAC Day for a special online event with Professor Bruce Scates, ANU historian, author and producer of the series ‘Australian Journey’. In this interactive broadcast, Bruce will present a vivid look at how our nation remembers war, and tell the stories of men and women touched by it
The Lewis & Clark sketchbook: based on 1804-1806 journey of Lewis & Clark
This sketchbook follows the footsteps of two American explorers, Meriwether Lewis and William Clark, as they explored and mapped the Missouri and Columbia Rivers from 1804-1806, and made contact with the Indigenous peoples along the way. The author has also included travel suggestions and a travel itinerary for those interested in following in the footsteps of Lewis and Clark. The last part of the sketchbook contains the sketches of schoolchildren as they sketched their interpretations of selected diary entries of the Lewis and Clark 1804-1806 journey of exploration.monograp
Eurytemora americana Williams, 1906, not Eurytemora affinis (Poppe, 1880), inhabits the Bahía Blanca estuary, Argentina
The aim of this report is to clarify the taxonomical identity of the species of Eurytemora (Copepoda, Calanoi- da) present in the Bahía Blanca estuary, Argentina. Observations of taxonomical details were performed and the results led us to conclude that this species is Eurytemora americana Williams, 1906 and not Eurytemora affinis (Poppe, 1880), as pre- viously identified. E. americana is a recent invader in this estuary and could have been accidentally introduced with ballast water of shipsFil: Hoffmeyer, Monica Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto Argentino de Oceanografía. Universidad Nacional del Sur. Instituto Argentino de Oceanografía; ArgentinaFil: Frost, Bruce W. University of Washington; Estados UnidosFil: Castro, María Belén. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto Argentino de Oceanografía. Universidad Nacional del Sur. Instituto Argentino de Oceanografía; Argentin
Debra Bruce, 25th Annual Literary Festival
Debra Bruce is the author of three books of poetry, Pure Daughter, Sudden Hunger, and most recently, What Wind Will Do. Her poems have appeared in such journals as The American Poetry Review, The North American Review, Poetry, and The Virginia Quarterly Review, and she has received grants in writing from the National Endowment for the Arts, the National Endowment for the Humanities, and the Illinois Arts Council. She is Associate Professor of English at Northeastern Illinois University
Informed learning: a narration
In this salon conversation, Christine Bruce, author of ‘Informed Learning’ will read the narratives underpinning the book's chapters. The intention is to reveal the narrative thread which reflects a journey of the scholarship of learning and teaching. In the course of that journey, two new academics engage in learning and teaching innovation, securing their own professional development, and creating unexpected opportunities for colleagues and the wider university in the process. Informed learning is a way of thinking about the educational process in terms of using information to learn. Information is often the hidden element in curriculum...present, critical, not always explicitly recognised. Thinking in terms of informed learning provides a language and an approach that highlights the role of information in the learning process, encouraging all members of the learning community to be aware of that role, and benefit from it. The narratives will serve as openers to discussion about the experience of learning and teaching with attention to information environments.\ud
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Christine Bruce (2008) <i>Informed Learning</i>. Chicago, American College and Research Libraries.\ud
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<a href="http://eprints.qut.edu.au/view/person/Bruce,_Christine.html">Christine Bruce QUT ePrints profile</a
Margaret Carnegie, Holbrook, New South Wales, ca. 1975, 1 [picture] /
Margaret Carnegie lived at Kildrummie near Holbrook. She is the author of Friday Mount and Morgan the Bold Bushranger and is a collector of art.; Part of: Sheilas, a tribute to Australian women collection, ca. 1975.; Title devised by cataloguer based on information supplied by photographer.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.pic-vn4227509
Bruce Weigl, 11th Annual ODU Literary Festival
Bruce Weigl, a member of the Associated Writing Programs Board of Directors, is the author of five books of poetry: A Sackfill of Old Quarrels, Executioner, A Romance, The Monkey Wars and most recently Song of Napalm (1988). His poetry, essays, articles and reviews have appeared in many periodicals. His work has received a Pushcart Prize, a National Endowment for the Arts Fellowship, a Breadloaf Fellowship, and a Yaddo Fellowship. During 1967-68 he served with the First Air Cavalry in Vietnam; in 1985 he revisited Vietnam. A former member of the creative writing faculty at Old Dominion University, he now teaches at Pennsylvania State University
Prolonged recombinant pregnancy hormone use in BRCA1 and BRCA2 mutation carriers
Background
An early first full-time pregnancy substantially reduces the risk of developing breast cancer later in life. Extensive studies indicate that this protective effect is mediated by the pregnancy hormone human chorionic gonadotrophin (hCG).
Methods
In this proof-of-concept study 33 women with a BRCA mutation received recombinant-hCG (r-hCG). A 4-mm breast biopsy was obtained before (T1) and after 12 weeks of r-hCG injections (T2), as well as 6 months later (T3). The tissue was examined using RNA-sequencing methodology to determine if the 'high-risk' transcriptomic signature was converted to a 'low-risk' signature as in an early first full-time pregnancy. A stringent clinical safety monitoring was performed.
Results
The r-hCG administration was well tolerated in all participants. No clinically relevant changes were observed. In 25 women, the RNA quality was good for RNA sequencing in all three breast tissue biopsies. In response to the r-hCG, we observed 1907 differentially expressed genes (DEGs) (1032 up, 875 down) at T2 vs. T1 and 1065 DEGs (897 up, 168 down) at T3 vs. T1 in the group of women (n = 11) not using any hormonal contraceptives during the study. There was no response at T2 vs. T1 and a small number of DEGs, 260 (214 up, 46 down) at T3 vs. T1 in the group of 14 women using contraceptives.
Conclusions
In summary, r-hCG has a remarkable effect on the gene expression profile of breast tissues from BRCA1/2 carriers who did not use any contraception. This opens an opportunity for a novel preventive strategy to reduce the incidence of breast cancer
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