128 research outputs found

    Semen Parameter Profile of Infertile Men Visiting Andro-Urology Clinic

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    Infertility is the inability of a sexually active, non-contracepting couple to achieve spontaneous pregnancy in one year. Male infertility is found in about 7% of couples globally and one of the factors associated with it is impaired semen parameter. This study aimed to understand the semen parameter profile of infertile male patients in andro-urology clinics. This is a retrospective-descriptive study from medical records of patients in Dr. Cipto Mangunkusumo Hospital from 2010 to 2020. About 1656 infertile males went to the clinic and. 81 (4.9%) were found to have normal semen parameter, 879 (53%) had azoospermia, and 777 (46%) have at least one impaired parameter (sperm concentration, motility, and morphology). The mean spermatozoa concentration was 16.74 + 29.17 mil/ml, total motility rate was 27.87 + 24.3 %, and normal morphology was 13.19 + 19.50 %. In conclusion, most of the patients came to the clinic with azoospermia, and the percentage was above other studies. Therefore, further research is needed to ascertain the reason for the high percentage of azoospermia patients.  Profil Parameter Semen pada Laki-laki Infertil yang Berkunjung ke Klinik Andro-Urologi  Infertiltas laki-laki merupakan masalah pada 7 % pasangan yang menikah dan melakukan sanggama secara teratur tanpa alat kontrasepsi selama lebih dari satu tahun, namun belum memiliki keturunan. Salah satu penyebab infertiltas laki-laki adalah gangguan pada parameter semen. Penelitian ini bertujuan untuk mengetahui profil parameter semen pada laki-laki infertil yang berkunjung ke klinik andro-urologi. Penelitian retrospektif dan deskriptif ini menggunakan data rekam medis pasien infertilitas laki-laki yang mengunjungi klinik andro-urologi Rumah Sakit dr. Cipto Mangunkusumo (RSCM) tahun 2010 hingga 2020 dan terdapat 1656 pasien infertiltas laki-laki. Sebanyak 81 (4,9%) pasien memiliki parameter semen normal, azoospermia 879 (53%) dan 777(46%) dengan gangguan pada salah satu atau lebih parameter semen (jumlah, gerakan, bentuk spermatozoa). Rerata konsentrasi spermatozoa 16,74 + 29,17 juta/ml; Rerata motilitas spermatozoa 27,87 + 24,3% dan rerata morfologi normal 13,19 + 19,50%. Disimpulkan sebagian besar pasien infertilitas laki-laki yang datang ke klinik andro-urologi RSCM dalam keadaan azoospermia. Pasien infertilitas laki-laki dengan azoospermia jauh lebih tinggi dibandingkan dengan kepustakaan sehingga diperlukan penelitian lebih lanjut untuk mencari penyebab tingginya angka azoospermia.  &nbsp

    USAGE OF SUPPORTING PAD FOR SUPINE PCNL: A SINGLE CENTER EXPERIENCE

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    Objective: This study aims to compare the safety, efficacy, and other surgical outcomes of supine PCNLs performed with and without the use of supporting pad. Material & Methods: We enrolled 27 patients who undergone PCNL procedure with supine position for renal stones with all sizes between January - December 2019. Divided into two groups, operated with and without supporting pad, with 13 and 14 patients respectively. Inclusion criteria are patients with renal stones, including staghorn, multiple calyx, and proximal ureteral stones. Meanwhile, pediatric patients under 12 years old, uncorrectable bleeding disorders, active urinary infection, and pregnancy are excluded. Results: Our observation showed no statistically significant difference between the two groups, although blood loss and length of stay in supporting pad showed better results. A statistically significant difference was found in stone-free-rate (P = 0.006) favoring in supine PCNL with supporting pad. Conclusion: Supine PCNL with support padding may be a safe and more effective choice to treat renal stones. Nevertheless, the patient’s anatomic variations may influence this. Thus, a prospective study with a larger population is needed to verify our outcomes

    Effects of Pipemidic Acid, Phenazopyridine HCL and Sodium Diclofenac on Pain Perception Following Endoscopic Urological Surgery: Double-blinded Randomized-Controlled Trial

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    Aim: to evaluate the analgesic effect, the side effects and the safety of analgesics following endoscopic urological procedure. Methods: eighty patients who underwent endoscopic urological surgery at Kardinah Hospital, Tegal from June to July 2015 were divided into four groups. The experimental group was administered analgesic for 4 days pipemidic acid (A) 400 mg bid, or phenazopyridine (B) 200 mg tid, or sodium diclofenac (C) 50 mg bid and the control (D) group was administered placebo tid for 4 days. The analgesic effects were assessed using Visual Analog Scale (VAS). Association between variables was assessed using Cramers V and Kruskall Wallis. Results: the endoscopic urological procedures consisted of 30 patients for URS, 6 patients for lithotripsy, 17 patients for TURP, 24 patients for removal JJ stent and 3 patients for cystoscopy. The mean age of group A, B, C and D (control) was 50.1 (13.7), 50.7 (14.8), 49.1 (13.4), and 49.6 (14.3) years, respectively, and follow-up period was 7 days. The VAS score in all experimental groups was less than control group on day 1 to 7 following endoscopic urological procedures (p0.05). Group A demonstrated a more favourable analgesic effect than B and C (p<0.05). No serious side effects were detected in any of the cases. Conclusion: we conclude that oral analgesics are effective for pain relief following endoscopic urological surgery. Pipemidic acid was found to have a superior analgesic effect than phenazopyridine HCl and sodium diclofenac

    URINARY STONE RISK PROFILE IN STONE FORMER PATIENT

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    Objective: We were comparing the urinary stone risk profiles in stone former subjects group with normal population (non stone-former) group. Material & method: In this study, each group consist of 10 subjects. Urine samples used was a 24-hour-urine. All subjects in this study were previously informed and voluntarily participating. Inclusion criteria in this study were adult, stone free, residing in Jakarta. Measurement was performed in Department of Molecular Biology and Biochemistry Faculty of Medicine Indonesia University. Statistical analysis was performed using SPSS 20 (Chicago, USA) with Student’s t-test or Mann-Whitney (p 0.05) in sodium, creatinine, calcium, magnesium, oxalate, and citrate levels. Conclusion: There were no significant differences in urinary stone promoting and inhibiting factors between two groups. Bigger number of sample size with better sampling method must be conducted for future studies

    RISK FACTORS IN SEVERE ERECTILE DYSFUNCTION POPULATION

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    Objective: To find the risk factors of severe erectile dysfunction. Material & methods: This Cross sectional study subjects completed the questionnare at the time of diagnosing Erectile Dysfunction (ED). Amount of 297 ED patients with mean age of 49.08 ± 13.69 years were enrolled consecutively at Urology Outpatient Clinic from 2005 to 2012. The questionnaire consisted of marital status, educational status, and occupation, comorbidities, habits, and International Index of Erectile Dysfunction-5 (IIEF-5) questionnare. We compared population proportion of ED severity (severe vs not severe) between sociodemographic, comorbidities and habits group and we also compared the mean of ED onset age and ED duration between those groups. Results: Of the patients, 29.3% were classified as severe ED, and 70.7% were classified other than severe ED (mild, mild-moderate, etc). The median of ED onset age was 47 years (46.64 ± 13.77 years) and the median of ED duration was 52 weeks (126.75 ± 167.69 weeks) ranged from 1 to 1040 weeks. We found status of low education level, unemployed, not married and having diabetes mellitus could increase the risk of having severe ED in ED population with each prevalence ratio was 1.44 (1.12-1.87), 2.02 (1.20-3.42), 1.91 (1.10-3.30), 2.01 (1.30-3.12). Not married group was also found have an earlier mean of ED age onset (mean difference 6.78 (2.37-11.19) years. Conclusion: We found that education level, occupation status, marital status and diabetes mellitus contributes in determining ED severity

    Factors affecting stone free rate of primary percutaneous nephrolithotomy on staghorn calculi: a single center experience of 15 years [version 1; referees: 2 approved]

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    Objectives: Percutaneous nephrolithotomy on staghorn calculi is challenging for urologists because it is difficult to remove all of the stones. The purpose of this study was to evaluate the associated factors of stone-free rate after primary percutaneous nephrolithotomy on staghorn calculi in a large series of patients at a single, tertiary referral, endourologic stone center. Methods: We collected data from medical record between January 2000 and December 2015. A total of 345 primary percutaneous nephrolithotomy procedures were performed for patients with staghorn calculi. This study included both and made no distinction between partial and complete staghorn calculi. Stone-free is defined as the absence of residual stones after undergoing percutaneous nephrolithotomy for the first time. Significant factors from univariate analysis that correlated with stone-free rate after primary percutaneous nephrolithotomy of staghorn stone were further analyzed using multivariate regression analysis. Results: The mean patient age was 52.23±10.38 years. The stone-free rate of percutaneous nephrolithotomy monotherapy was 62.6%. The mean operating time was 79.55±34.46 minutes. The mean length of stay in hospital was 4.29±3.00 days. Using the chi-square test, history of ipsilateral open renal stone surgery (p = 0.01), stone burden (p = < 0.001), and type of anesthesia (p = 0.04) had a significant impact on the stone-free. From multivariate analysis, the history of ipsilateral open renal stone surgery [OR 0.48; 95% CI 0.28-0.81; p 0.01] and the stone burden [OR 0.28; 95% CI 0.18-0.45; p 0.00] were significant independent risk factors for stone-free

    Urinary stone characteristics of patients treated with extracorporeal shock wave lithotripsy in Cipto Mangunkusumo Hospital Jakarta, 2008–2014: a gender analysis

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    Background: The incidence of urinary stone patient in Indonesia has increased every year in both genders. Data showed that urolithiasis was higher in male rather than female. The aimed of this study was to describe the characteristics of urinary stone found in patient who underwent extracorporeal shock wave lithotripsy (ESWL) at Cipto Mangunkusumo Hospital, Jakarta from 2008–2014. Methods: Data obtained from ESWL medical record Cipto Mangunkusumo Hospital, Jakarta from 2008–2014. We obtained 5,174 out of 6,020 data due to incompleteness data record. We sorted data records by gender, age, stone location, stone opacity, size of the stone, and history of ESWL, and analyzed by statistic tools (SPSS v 20 for Mac). Results: From 5,174 records, we found that the incidence of urinary stones was two times higher in male rather than female (66.3%:33.64%), occurred mostly in productive age (65.2% male, 65.9% female). Unilateral kidney stone was most common location found for both gender (50.2% male, 57.2% female), and most frequent site located in calyx inferior (24.8% male, 28.9% female). About 72.9% stone was radiopaque (73.7% male and 71.5% female). The mean size of the stone in male and female was 11.34±7.15 mm and 11.90±7.54 mm, respectively. This study also showed that 79.3% patients came for first ESWL. Conclusion: Urinary stone founds two times higher in male than female, and mostly occurs on their productive ages. Unilateral kidney stone in calyx inferior become the most common stone found in both gender. Most of the stone has radiopaque opacity

    Success Rate of Pregnancy after PESA/TESE and ICSI in Jakarta

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    Male infertility is a major problem in infertility. It can be caused by obstructive azoospermia. Sperm retrieval surgery (SRS) is the best approach to gain the sperm used Intra Cystoplasmic Sperm Injection (ICSI). However, the success rate of pregnancy after SRS and ICSI in Cipto Mangunkusumo National Hospital has not yet been defined. There were 123 patients had SRS with most of them performed PESA. Sperm were found in more than 77% of patients with most of them directly performed ICSI. Only 40 patients could be contacted with average age of husband, wife, and duration of marriage were 40.3 + 8.2, 33.2 + 5.1, 7.6 + 4.6 years old respectively. Most of patients were suffered from primary infertility. The success rate of pregnancy is 72.5%, with success rate of birth is 30.0%. There are 2 patients waiting for delivery date. Sperm retrieval surgery such as PESA/TESE is the best approach to gain sperm in obstructive azoospermia patient. The success rate of pregnancy after PESA/TESE and ICSI is high with almost half of patients have succeed in giving birth
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