140 research outputs found
sj-docx-1-eso-10.1177_23969873221139410 – Supplemental material for Prolonged cardiac monitoring for stroke prevention: A systematic review and meta-analysis of randomized-controlled clinical trials
Supplemental material, sj-docx-1-eso-10.1177_23969873221139410 for Prolonged cardiac monitoring for stroke prevention: A systematic review and meta-analysis of randomized-controlled clinical trials by Georgios Tsivgoulis, Lina Palaiodimou, Sokratis Triantafyllou, Martin Köhrmann, Polychronis Dilaveris, Konstantinos Tsioufis, Gkikas Magiorkinis, Christos Krogias, Peter D Schellinger, Valeria Caso, Maurizio Paciaroni, Mukul Sharma, Robin Lemmens, David J Gladstone, Tommaso Sanna, Rolf Wachter, Gerasimos Filippatos and Aristeidis H Katsanos in European Stroke Journal</p
Prolonged cardiac monitoring for stroke prevention: A systematic review and meta-analysis of randomized-controlled clinical trials
Introduction: Prolonged cardiac monitoring (PCM) substantially improves the detection of subclinical atrial fibrillation (AF) among patients with history of ischemic stroke (IS), leading to prompt initiation of anticoagulants. However, whether PCM may lead to IS prevention remains equivocal. Patients and methods: In this systematic review and meta-analysis, randomized-controlled clinical trials (RCTs) reporting IS rates among patients with known cardiovascular risk factors, including but not limited to history of IS, who received PCM for more than 7 days versus more conservative cardiac rhythm monitoring methods were pooled. Results: Seven RCTs were included comprising a total of 9048 patients with at least one known cardiovascular risk factor that underwent cardiac rhythm monitoring. PCM was associated with reduction of IS occurrence compared to conventional monitoring (Risk Ratio: 0.76; 95% CI: 0.59–0.96; I 2 = 0%). This association was also significant in the subgroup of RCTs investigating implantable cardiac monitoring (Risk Ratio: 0.75; 95% CI: 0.58–0.97; I 2 = 0%). However, when RCTs assessing PCM in both primary and secondary prevention settings were excluded or when RCTs investigating PCM with a duration of 7 days or less were included, the association between PCM and reduction of IS did not retain its statistical significance. Regarding the secondary outcomes, PCM was related to higher likelihood for AF detection and anticoagulant initiation. No association was documented between PCM and IS/transient ischemic attack occurrence, all-cause mortality, intracranial hemorrhage, or major bleeding. Conclusion: PCM may represent an effective stroke prevention strategy in selected patients. Additional RCTs are warranted to validate the robustness of the reported associations
Long-term follow-up of patients with implantable cardioverter defibrillators in Greece: The Cretan Registry
P-wave dispersion measurement: Methodological considerations
Well-known difficulties in defining P-wave onset and offset may restrict the accuracy and reproducibility of P-wave dispersion measurements. To achieve greater precision in measuring P-wave dispersion, simultaneous digital recording of all 12 ECG leads and onscreen measurement of P wave characteristics is mandatory to examine atrial fibrillation risk
Periprocedural anticoagulation in patients undergoing cryoballoon ablation for atrial fibrillation
Big data analysis from Sweden confirms that resting heart rate in late adolescence is significantly associated with incident heart failure and all-cause mortality
Long-term follow-up of patients with implantable cardioverter defibrillators in Greece: The Cretan Registry
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