110,950 research outputs found

    7 i fr r> \ S.1013.

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    Cambridge, Londons New York; Cambridge University Press; (1933). 8, 275 pIntroductory statistics with applications in general insurance. By I. B. Kossack, J. H. Pollard, B. Zehnwirt

    Vascular endothelial growth factor restores delayed tumor progression in tumors depleted of macrophages

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    Genetic depletion of macrophages in Polyoma Middle T oncoprotein (PyMT)-induced mammary tumors in mice delayed the angiogenic switch and the progression to malignancy. To determine whether vascular endothelial growth factor A (VEGF-A) produced by tumor-associated macrophages regulated the onset of the angiogenic switch, a genetic approach was used to restore expression of VEGF-A into tumors at the benign stages. This stimulated formation of a high-density vessel network and in macrophage-depleted mice, was followed by accelerated tumor progression. The expression of VEGF-A led to a massive infiltration into the tumor of leukocytes that were mostly macrophages. This study suggests that macrophage-produced VEGF regulates malignant progression through stimulating tumor angiogenesis, leukocytic infiltration and tumor cell invasion

    Pollard J.H. — Mathematical models for the growth on human populations

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    L.-B. H. Pollard J.H. — Mathematical models for the growth on human populations. In: Population, 31ᵉ année, n°2, 1976. p. 503

    RRS Discovery Cruise 223, 28 Sep-19 Nov 1996. VIVALDI ‘96

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    RRS Discovery Cruise 223, VIVALDI ‘96, was a contribution to the UK WOCE Community Research Programme. The pattern of SeaSoar sections was designed to enable the upper ocean circulation in the Subpolar gyre of the North Atlantic to be mapped and in particular the course of the North Atlantic and Irminger Currents within the region to be determined. The sparse deep CTD survey was required to complement the upper ocean survey and provide estimates of total mass transport and an ‘oceanographic opinion poll’ of water mass properties, including CFCs.The cruise commenced by repeating the well-established Rockall Trough CTD Section from Barra Head to Rockall Island. This was then extended north to Lousy Bank from where a CTD section measured before by Saunders across the Iceland Basin was repeated. From then onwards the cruise consisted principally of SeaSoar/ADCP sections interspersed with deep CTD casts (see track plot, Fig.1). These were placed on the ‘Vivaldi Grid’ (round 3° of latitude and multiples of 300 km west of 20°W) where possible, though the complex topography was taken into account. East of Greenland a more intense CTD section of 6 stations (12995-13001) was made along 60°N to cut the East Greenland Current. In addition 7 profiling floats were deployed in the Irminger Basin

    The effect of large-scale inhomogeneities on small-scale structure in a turbulent flow

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    Kolmogorov’s equation, which indicates that the mean energy is transported by both turbulent advection and molecular diffusion at any scale of flow, cannot be balanced for flows encountered in the laboratory conditions at moderate range of Reynolds numbers. The main reason for this imbalance is inhomogeneous large-scales. In this work, a new generalized form of Kolmogorov’s equation is suggested for jet flows. The validity of this equation is investigated using hot-wire data obtained across the centreline of a round turbulent jet. In addition, the external intermittency and some other basic characteristics are studied

    Approximating the Stieltjes Integral via the Darst-Pollard Inequality

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    An approximation of the Stieltjes integral of bounded integrals and continuous integrators via the Darst-Pollard inequality is given. Applications for the generalised trapezoid formula and the Ostrowski inequality for functions of bounded variation are also provided

    Studies in numismatic method presented to Philip Grierson, Edited by C.N.L. Brooke, B. H. I. H. Stewart, J.G. Pollard and T. R. Volk.

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    Bompaire Marc. Studies in numismatic method presented to Philip Grierson, Edited by C.N.L. Brooke, B. H. I. H. Stewart, J.G. Pollard and T. R. Volk.. In: Revue numismatique, 6e série - Tome 27, année 1985 pp. 221-223

    MOBILE and the provision of total joint replacement

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    Modern joint replacements have been available for 45 years, but we still do not have clear indications for these interventions, and we do not know how to optimize the outcome for patients who agree to have them done. The MOBILE programme has been investigating these issues in relation to primary total hip and knee joint replacements, using mixed methods research

    TCCON data from Lauder (NZ), 120HR, Release GGG2014.R0

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    The Total Carbon Column Observing Network (TCCON) is a network of ground-based Fourier Transform Spectrometers that record direct solar absorption spectra of the atmosphere in the near-infrared. From these spectra, accurate and precise column-averaged abundances of atmospheric constituents including CO2, CH4, N2O, HF, CO, H2O, and HDO, are retrieved. This data set contains observations from the TCCON station at Lauder, New Zealand.Contact person: Dave Pollard [email protected]
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