3,040 research outputs found
Steven Yedinak Interview
No full textLTC (RET) Steven M. Yedinak commissioned in the U. S. Army Infantry in 1963 and subsequently spent 26 years in Special Forces and Airborne Infantry. He served two combat tours in Vietnam (1966-67 & 1971-1972), and started the Mobile Guerrilla Force. He is the author of Hard to Forget: An American with the Mobile Guerrilla Force in Vietnam (Random House, 1998). He retired from the Army in 1989
Steven M. Lowenstein Collection - Addenda. 1960s-2007
No full textThe Steven Lowenstein Collections documents professional activities of Steven Lowenstein, writer, researcher, historian, and teacher. Documents comprising the collection reflect his interests in a wide spectrum of topics related to Jews and Judaism, such as modernity and tradition and their influence on the religion and common folks; Berlin Jews of the upper strata; similarities and differences between agrarian/rural and urban Jews; popular and official Judaism; secular and religious Jews; and other Jewish related topics. However, there is a very small amount of materials related to his professional activities other than research and writing.There are two distinct types of materials – correspondence and manuscripts: Correspondence collected here pertain to Steven Lowenstein’s writings and publishing efforts; his teaching activities; conferences; writings by others; and research projects. Additional correspondence dealing with Steven Lowenstein’s editorial work, writings, and publishing efforts is found in Series II: Writings.Writings collected here range from large scale works to short essays, reviews and lectures. By and large, his manuscripts are accompanied by very extensive supplementary materials such as notes, research files, correspondence with publishers regarding publications and publication’s rights, small amount of correspondence with colleagues, and printed materials. Additionally, there are legal documents, such as agreements and permissions; small amount of printed materials, and photographs.Steven Lowenstein, scholar, teacher, and a writer was born in New York in 1945 into a family of German –Jewish refugees. He received his master’s degree from Princeton University in 1969 and went on earning a doctorate degree from Princeton University in 1972. He taught at a number of universities, including Columbia University and Monmouth College, and worked as a researcher at YIVO and the Leo Baeck Institute. In the late 1970s Dr. Lowenstein moved to California where he taught Jewish history at the American Jewish University. He is the author of a large number of scholarly works, including The Jewish Cultural Tapestry: International Jewish Folk Traditions; The Berlin Jewish Community: Enlightenment, Family and Crisis, 1770-1830; and Frankfurt on the Hudson: The German-Jewish Community of Washington Heights, 1933-1983, Its structure and Culture.digitize
Landsat MSS classification of fire fuel types in Wood Buffalo National Park, northern Canada
No full textJ1: Global Ecology & Biogeography Letters; M3: Article; Milne, David Franklin, Steven E. Wilson, Bradley A. Ghitter, Geoff Heathcott, Mark McCaffrey, Thomas M. Ow, Charlotte F. Y.; Source Information: Mar1994, Vol. 4 Issue 2, p33; Subject Term: FOREST fires; Author-Supplied Keyword: Canada (Wood Buffalo National Park); Author-Supplied Keyword: Forest fire; Author-Supplied Keyword: Fuel type classification; Author-Supplied Keyword: Landsat data; Number of Pages: 0p; Document Type: Articl
Vascular endothelial growth factor restores delayed tumor progression in tumors depleted of macrophages
No full textGenetic depletion of macrophages in Polyoma Middle T oncoprotein (PyMT)-induced mammary tumors in mice delayed the angiogenic switch and the progression to malignancy. To determine whether vascular endothelial growth factor A (VEGF-A) produced by tumor-associated macrophages regulated the onset of the angiogenic switch, a genetic approach was used to restore expression of VEGF-A into tumors at the benign stages. This stimulated formation of a high-density vessel network and in macrophage-depleted mice, was followed by accelerated tumor progression. The expression of VEGF-A led to a massive infiltration into the tumor of leukocytes that were mostly macrophages. This study suggests that macrophage-produced VEGF regulates malignant progression through stimulating tumor angiogenesis, leukocytic infiltration and tumor cell invasion
Steven Bryant’s Solace: a conductor’s analysis and performance guide
No full textThe purpose of this study was to examine Solace, a musical composition for wind ensemble, by Steven Bryant composed for the University of North Carolina at Greensboro Wind Ensemble and premiered at the 2013 College Band Directors National Association National Conference. Through a conductor's analysis and performance guide, the author provided insight and background knowledge to all future performers and interpreters of the work through unique first hand accounts from commission to premiere performance. The research method included three processes: 1. A detailed analysis of the musical score, 2. The observation of rehearsals and recording sessions during preparation for the premiere performance of Solace by the University of North Carolina at Greensboro Wind Ensemble, Kevin M. Geraldi, conductor, 3. Extensive interviews of Steven Bryant, composer and Kevin M. Geraldi, conductor. Through examination of prior research on electro-acoustic works for wind ensemble, the author examined Solace within those constructs. Because of the blurring of lines between electronics and acoustic sound, the author further identified Solace as a unique musical composition within the electro-acoustic genre
Comparison of thermal modeling, microstructural analysis, and Ti-in-quartz thermobarometry to constrain the thermal history of a cooling pluton during deformation in the Mount Abbot Quadrangle, CA
No full textGranitic plutons commonly preserve evidence for jointing, faulting, and ductile fabric
development during cooling. Constraining the spatial variation and temporal evolution of temperature
during this deformation could facilitate an integrated analysis of heterogeneous deformation over multiple
length-scales through time. Here, we constrain the evolving temperature of the Lake Edison granodiorite
within the Mount Abbot Quadrangle (central Sierra Nevada, CA) during late Cretaceous deformation by
combining microstructural analysis, titanium-in-quartz thermobarometry (TitaniQ), and thermal modeling.
Microstructural and TitaniQ analyses were applied to 12 samples collected throughout the pluton,
representative of either the penetrative ‘‘regional’’ fabric or the locally strong ‘‘fault-related’’ fabric.
Overprinting textures and mineral assemblages indicate the temperature decreased from 400–5008C to
<3508C during faulting. TitaniQ reveals consistently lower Ti concentrations for partially reset fault-related
fabrics (average: 1264 ppm) than for regional fabrics (average: 31612 ppm), suggesting fault-related
fabrics developed later, following a period of pluton cooling. Uncertainties, particularly in TiO2 activity,
significantly limit further quantitative thermal estimates using TitaniQ. In addition, we present a 1-D heat
conduction model that suggests average pluton temperature decreased from 5858C at 85 Ma to 3328C at 79
Ma, consistent with radiometric age data for the field. Integrated with the model results, microstructural
temperature constraints suggest faulting initiated by 83 Ma, when the temperature was nearly uniform
across the pluton. Thus, spatially heterogeneous deformation cannot be attributed to a persistent
temperature gradient, but may be related to regional structures that develop in cooling plutons.University of Delaware. Department of Geological Sciences
Author Correction: Identification of functional tetramolecular RNA G-quadruplexes derived from transfer RNAs
No full textThe original version of this Article contained an error in the spelling of the author Steven M. Coyne, which was incorrectly given as Stephen M. Coyne. This has now been corrected in both the PDF and HTML versions of the Article.</jats:p
Regulation of neural stem cell and glioblastoma stem cell quiescence by FOXG1 and Wnt/beta-catenin
No full textThe balance of stem cell quiescence versus proliferation must be tightly regulated under normal
homeostasis and becomes disrupted in cancers. The brain cancer glioblastoma is driven by cells
with neural stem cell characteristics. These glioblastoma stem cells (GSCs) can reside in
dormant, quiescent and proliferative states, yet the molecular transitions between these remain
poorly understood. Quiescent GSCs are refractory to anti-mitotic cytotoxic therapies, and
contribute to regrowth of the tumour; therefore elucidating molecular pathways that control
GSC exit from quiescence may uncover new therapeutic strategies. The role of Wnt signaling
in GBM has remained enigmatic. Here I show that the transcription factor FOXG1, which is
frequently overexpressed in GSCs, cooperates with Wnt signaling to drive efficient exit from
quiescence. However, Wnt signaling is dispensable once GSCs are fully proliferative. Using a
phenotypic chemical screen (303 small molecule regulators of stem cell related pathways) I
identified a potent synergy between glycogen synthase kinase 3 (GSK3) inhibitors and FOXG1
in driving exit from NSC quiescence. Pharmacological and genetic perturbations confirmed
that this was due to activation of the Wnt/beta catenin pathway. The FOXG1/Wnt synergy is
also relevant in vivo, and in human glioblastoma cell models. Mechanistically, these data
suggest that the excessive FOXG1 both leads to an accumulation of beta-catenin and sequesters
the Wnt/TCF co-repressor Groucho/TLE, thereby derepressing Wnt/beta catenin target genes
and enabling their maximal activation. I conclude that FOXG1 and Wnt cooperate in the critical
process of exiting the quiescent state. These findings suggest inhibition of Wnt signaling will
have limited impact on the proliferative GSC compartment, but may be critical in preventing
reactivation of the quiescent cells that drive regrowth of the tumour after chemo- and
radiotherapy
M. Patrick Graham & Steven L. McKenzie (ed.), The Chronicler as Author. Studies in Text and Texture, Sheffield, Sheffield Academic Press, 1999, (Journal for the Study of the Old Testament, Supplement Series, 263), ISBN 1-84127-057-1
No full textRobert Philippe de. M. Patrick Graham & Steven L. McKenzie (ed.), The Chronicler as Author. Studies in Text and Texture, Sheffield, Sheffield Academic Press, 1999, (Journal for the Study of the Old Testament, Supplement Series, 263), ISBN 1-84127-057-1. In: Revue d'histoire et de philosophie religieuses, 80e année n°2, Avril-juin 2000. p. 297
The Driving Force Behind Theater : an Examination of Three Facets of Professional Theater : The Theater, Theatrical Companies, and the Freelance Designer
No full textiv, 66 p.The author interned with freelance lighting and stage designer Steven R. Espach, working on three shows for two non-for-profit theater companies on Long Island, New York.East Hampton, New York
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