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    Intramural distribution of neuron specific enolase (NSE) in the human gastrointestinal tract.

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    NSE concentrations were measured by radioimmunoassay in the main separated layers of the human gastrointestinal tract. At all levels, a similar pattern of distribution of this protein was found, primarily parallel to that of nerve elements. Lower amounts of NSE were detected in the separated mucosal epithelium, containing the endocrine cells

    Immunocytochemistry of serotonin-containing nerves in the human gut.

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    An immunocytochemical technique, using L-tryptophan enhancement and paraformaldehyde fixation, has been successfully applied for the demonstration of serotonin-containing neurons in the human enteric nervous system. Throughout the intestine, serotonin-immunoreactive nerves were mainly detected in the myenteric plexus and, to a smaller extent, in the submucous plexus, while hardly any nerve fibres were seen in the mucosa. This approach provides a useful tool for the investigation of neuropathological conditions of the gut
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