106,670 research outputs found
Evolution of the Insertion-Deletion Mutation Rate Across the Tree of Life
No full textCitation: Sung, W., Ackerman, M. S., Dillon, M. M., Platt, T. G., Fuqua, C., Cooper, V. S., & Lynch, M. (2016). Evolution of the Insertion-Deletion Mutation Rate Across the Tree of Life. G3-Genes Genomes Genetics, 6(8), 2583-2591. doi:10.1534/g3.116.030890/-/DC1Mutations are the ultimate source of variation used for evolutionary adaptation, while also being predominantly deleterious and a source of genetic disorders. Understanding the rate of insertion-deletion mutations (indels) is essential to understanding evolutionary processes, especially in coding regions, where such mutations can disrupt production of essential proteins. Using direct estimates of indel rates from 14 phylogenetically diverse eukaryotic and bacterial species, along with measures of standing variation in such species, we obtain results that imply an inverse relationship of mutation rate and effective population size. These results, which corroborate earlier observations on the base-substitution mutation rate, appear most compatible with the hypothesis that natural selection reduces mutation rates per effective genome to the point at which the power of random genetic drift (approximated by the inverse of effective population size) becomes overwhelming. Given the substantial differences in DNA metabolism pathways that give rise to these two types of mutations, this consistency of results raises the possibility that refinement of other molecular and cellular traits may be inversely related to species-specific levels of random genetic drift
PLATT, Juan R.
No full textIn a card sent to General Plutarco Elías Calles, Mr. A. G. Domínguez tells him that he sent two bottles of Bacanora to his office and that he wrote to Juan [R. Platt] recommending that he asks Federico Platt to send more Bacanora / Carta que envía el señor A. G. Domínguez al general PEC diciéndole que le remitió los dos garrafoncitos de Bacanora que quedaban en su oficina y que escribió a Juan [R. Platt] recomendándole que le pida a Federico Platt que le mande más Bacanora./
On the morphology and taxonomy of Griphobilharzia amoena Platt and Blair, 1991 (Schistosomatoidea), a dioecious digenetic trematode parasite of the freshwater crocodile, Crocodylus johnstoni, in Australia
No full textGriphobilharzia amoena Platt and Blair, 1991 was originally described as a dioecious trematode, parasitic in the circulatory system of the Australian freshwater crocodile, Crocodylus johnstoni, with the female completely enclosed in a gynecophoric chamber of the male and the 2 worms oriented anti-parallel to each other. A recent publication questions the original description, arguing that G. amoena is monoecious and, as a consequence, the species was transferred to Vasotrema Stunkard, 1928 (Spirorchiidae) as Vasotrema amoena n. comb. We provide photomicrographic evidence that the original description of G. amoena is correct and that Griphobilharzia Platt and Blair, 1991, is a valid monotypic genus containing G. amoena. An accurate understanding of the anatomy of G. amoena is not trivial and has implications for revealing the complex origins and evolution of the dioecious condition within the Schistosomatoidea.Thomas R. Platt, Eric P. Hoberg and Leslie A. Chishol
Rosati, Arre, Platt, & Santos - Study 2
No full textTrial data from Rosati, Arre, Platt, & Santos Study 2 (Positive socioemotional stimuli). Key for variables included as a separate tab in file
Rosati, Arre, Platt, & Santos - Study 1
No full textTrial data from Rosati, Arre, Platt, & Santos Study 1 (Negative socioemotional stimuli). Key for variables included as a separate tab in file
Fairground Platform Truck at Platt Fields
No full textG. A. Smith's platform truck photographed at Platt Fields, 16 August 1960. Scott negative number 3703. see also 178C57.1159
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