3,007 research outputs found
Benzazetidines and related compounds: synthesis and potential
No full textBenzazetidines are a class of N -heterocycles potentially very interesting for a variety of purposes, including biological applications and drug design. In the past, their high ring strain has hampered the development of trustable, general and efficient synthetic methodologies for their preparation. In this review article we aim to disclose all the literature contributions about the synthesis of these compounds and the study of their reactivity, from the early examples to the most recent synthetic approaches. Recently, we noted a growth of interest for this heterocycle pushed by the publication of novel synthetic methodologies based on palladium catalyzed intramolecular C-H amination and organocatalyzed ring closure of 2-( N -Boc-anilino)- α -ketoesters/amides
Rozpor ako východisko, láska ako smer u Simone Weilovej (Contradiction as base, Love as direction in writings of Simone Weil)
No full textArticle is explaining contradiction and love, Simone Weil‘s essential terms of hermeneutics of human Being. It introduces close relation of these terms with her understanding of God as well as with her overall concept of religion. Author also mentions Simone Weil‘s inspirations with philosophical and spiritual concepts of the East
“I beg you to tell me what has become of Djamila”: The Political Mobilization of Simone de Beauvoir’s Readers During the Boupacha Affair
No full textBy Sophia Millman This is a condensed version of a Masters thesis dedicated to the political mobilization of Simone de Beauvoir’s readers. The citations from the letters were translated from French by the author. *** On June 2, 1960, the French government ordered all copies of the daily Algiers edition of Le Monde seized and destroyed to suppress the publication of Simone de Beauvoir’s article “Pour Djamila Boupacha.” Beauvoir, a self-professed “woman of letters”, not “of action[1]”, and one ..
A comparative study of form and theology in the works of Flannery O'Connor and Simone Weil
No full textIn this comparative study of the form and theology of Flannery O'Connor and Simone Weil I interrogate how Weil's philosophical writings and her theology illuminate O'Connor's use of both narrative and non-fictional forms, and her Catholicism. The Introduction analyses how Weil's concept of superposed reading provides a new method of approaching both O'Connor, her writings, and O'Connor
studies, and focuses on how such apparently different women interconnect. Chapter One explores how both Weil and O'Connor attempt to write their theologies on the
souls of their readers yet are each subject to constraints imposed by form. Weil's concept of locating equilibrium between incommensurates is discussed, and her
distinctively philosophical approach to fictions and fictionality is used to investigate O'Connor's notion of prophetic fictions and the writer's role. Chapter Two assesses how both writers revivify Christian paradoxes. Weil's monstrous concept of affiiction, and O'Connor's use of the grotesque genre to jolt secular man into an
awareness of the sacred are scrutinised. Chapter Three studies how both writers consider an encounter between God and man is possible through the action of grace. My Conclusion interrogates how Weil's work can deepen our understanding of O'Connor's writings, and examines how successful O'Connor is at realising a truly
Christian literature. I conclude that despite being a writer of powerful fictions, O'Connor can not be totally successful in her mission as writer-prophet because
ultimately fiction escapes orthodoxy
Inter-hemispheric asymmetry of cerebral flow velocities during generalized spike-wave discharges.
No full textThe aim of this study was to verify the symmetry of cerebral blood flow changes
during the generalized spike-wave discharges of typical absence seizures. A
recording of mean flow velocity in the left and right middle cerebral arteries
and of electroencephalographic activity was performed simultaneously in two
subjects with multiple daily absence seizures. A total of 12 generalized
spike-wave discharges were recorded. Mean flow velocities showed a significant
increase during the discharges with respect to baseline. The increase of flow
velocity started simultaneously or a few seconds before the discharges. In 91.6 %
of all recordings, the percentage increase of mean flow velocity was
significantly higher in the left than in the right side (7.03 % +/- 3.3 vs 5.14 %
+/- 3.3; p < 0.1). The extent of the following decrease of flow velocity was also
significantly greater in the left than in the right side (-16.91 % +/- 8.1 vs
-14.07 % +/- 8.3; p < 0.01). These findings show an inter-hemispheric asymmetry
in cerebral blood flow during generalized spike-wave discharges in two patients
with absence seizures. Transcranial Doppler ultrasonography promises to be an
interesting approach to detect rapid changes in cerebral hemispheric activity not
otherwise recognizable
"Forced Behavior" as epileptic seizure: Description of a patient with neuronal migration disorder
No full textForced thinking and behavior can be true epileptic phenomena. Forced thinking, characterized by abrupt intrusion of thoughts, could be produced by an epileptic discharge in frontal or temporal lobes Epileptic forced thinking appears distinct from obsessive thoughts and compulsive urges. A male patient, teacher of optic pathophysiology, from the age of 40 showed short (2-3 minutes) episodes, characterized by a compulsive urge to speak technically as he would in his job. At the age of 43 he showed two nocturnal generalized seizures. An EEG was performed and it showed intercritical and critical anomalies on the left anterior regions. A magnetic resonance (MR) showed the presence of a neuronal migration disorder (sub-ependimal cotrical nodular heterotopia). Soon after, a therapy with carbamazepine 800 mg/die was started and all types of paroxystical manifestations disappeared. This case is interesting and intriguing because of the overlapping of epilepsy, forced behavior and neuronal migration disorders. Considering the anatomic systems involved in epilepsy and obsessive-compulsive disorder, we will discuss the differences and the common features of both disturbances
Microlinices benthovus Simone 2014
No full textbenthovus, Microlinices Simone, 2014 Microlinices benthovus Simone, 2014: 575–578 (figs 6A–J, 7A–H, 11A–C). Gastropoda, Naticidae Paratypes (22 spc): MZSP 105269. Paratypes 1 (15 spc): MZSP 105270. Paratypes 2 (16 spc): MZSP 105271. Paratypes 3 (7 spc): MZSP 105272. Localities: Brazil, Espírito Santo, off Itaúnas, Abrolhos Slope, 18°59' S, 37°50' W, MD55 sta. DC 73, 637 m depth, 27 May 1987; 1) 19°00' S, 37°48' W, MD55 sta. DC72, 950– 1050 m, 27 May 1987; 2) off Regência, 19°40' S, 37°48' W, MD55 sta. CB77, 790– 940 m depth, 27 May 1987; 3) off Itaúnas, Abrolhos Slope, 19°01' S, 37°47' W, MD55 sta. CB79, 1500–1575 m depth, 28 May 1987. Collectors: P. Bouchet, J.H. Leal and B. Métivier. Preservation: Dry. Remarks: Former MNHN, Paris. The catalogue number MZSP 105250 is mentioned twice in Simone’s (2014) paper, among the paratypes of M. ibitingus Simone, 2014 and M. benthovus. This duplicity was a mistake by the author: the latter is an erroneous designation and should be disregarded. The only valid paratype lots for M. benthovus are the ones shown above.Published as part of Cavallari, Daniel C., Dornellas, Ana Paula S. & Simone, Luiz Ricardo L., 2016, Second annotated list of type specimens of molluscs deposited in the Museu de Zoologia da Universidade de São Paulo, Brazil, pp. 1-59 in European Journal of Taxonomy 213 on page 10, DOI: 10.5852/ejt.2016.213, http://zenodo.org/record/384012
Was bringt die Föderalismusreform? Wahrscheinliche Effekte der geänderten Zustimmungspflicht
No full textThe recently enacted reform of German federalism is supposed to make legislation faster, more efficient and better. To what extent are these expectations justified? In order to assess the likely effects of the reform, this study uses a research design that was recently applied by the Research and Reference Services of the German Bundestag (parliament): we estimate the future effects of the reform by analyzing the impact it would have had on the legislation in the 14th and 15th term of the Bundestag if it had already been been in force at that time. In particular we ask: To what extent would the number of laws requiring the consent of the states' chamber, the Bundesrat, have been reduced? Which type of laws would have been affected by this reduction - the more controversial ones, or the less controversial ones? Which policy sectors would have seen the greatest reduction? How much would the reduction have increased the government's capacity to act effectively? Would the legislative process have been accelerated? -- Die verabschiedete Föderalismusreform soll die Gesetzgebung in Deutschland schneller, effizienter und besser machen. Inwiefern sind diese Erwartungen berechtigt? Zur Abschätzung der Reformfolgen auf die Bundesgesetzgebung folgen wir in dem vorliegenden Working Paper einer Vorgehensweise, die der Wissenschaftliche Dienst des Bundestages kürzlich in einer Studie angewandt hat: Die Auswirkungen der Föderalismusreform insbesondere auf die Zustimmungspflicht werden anhand der Gesetzgebung der 14. und 15. Legislaturperiode untersucht. Wir fragen insbesondere: Wie stark hätte sich der Anteil der Zustimmungsgesetze verringert, wenn die neuen Zustimmungsregeln schon in diesen beiden Legislaturperioden gegolten hätten? Wären eher zwischen Regierung strittige oder unstrittige Gesetze von der Zustimmungspflicht befreit worden? Welche Politikbereiche wären betroffen? Wie sehr hätte sich die politische Handlungsfreiheit der Bundesregierung erhöht? Wäre die Gesetzgebung durch die veränderten Zustimmungsregeln beschleunigt worden?
Idea ofiary u Simone Weil
No full textAutorka omawia ofiarę, jaką z samej siebie złożyła Simone Weil. Głównym celem autorki artykułu jest wykazanie, iż idea ofiary była najważniejszą myślą w życiu francuskiej filozof. W artykule ukazano myśl o ofierze w życiu i pismach intelektualistki, jak również analogie, które rzucają nowe światło na ofiarę Weil. Jako klucz do interpretacji i zrozumienia ofiary Weil, autorka analizuje myśl Emmanuela Levinasa oraz Józefa Tischnera.The author interprets the sacrifice that Simone Weil filed with itself. The main point of the present article is the assumption that the sacrifice Simone Weil was the most important idea of her life. A thought about the victim is portraying the article in the life and letters of the intellectual, as well as is portraying analogies which are shedding new light on the Weil victim. As the key to interpretation and understanding the her victim, the author is analysing the thought of Emmanuel Levinas and Jozef Tischner.Udostępnienie publikacji Wydawnictwa Uniwersytetu Łódzkiego finansowane w ramach projektu „Doskonałość naukowa kluczem do doskonałości kształcenia”. Projekt realizowany jest ze środków Europejskiego Funduszu Społecznego w ramach Programu Operacyjnego Wiedza Edukacja Rozwój; nr umowy: POWER.03.05.00-00-Z092/17-00
Panic disorder or epilepsy: a case report
No full textPsychiatric and neurological disturbances can show up with panic attack symptoms. This report illustrates the difficulty in distinguishing between panic disorder and epilepsy in a subgroup of epileptic patients that suffer panic attacks as symptoms of seizures. This is the first report of panic attacks due to a focal lesion involving the left temporal lobe and the second case of panic attacks related to a meningioma
- …
