1,721,053 research outputs found
Parietal centripetal and centrifugal thickening neovascularization in the descending anterior coronary artery Possible relations with the problem of collateral circulation
No full textLeft coronary arteries of 30 human
hearts, obtained at autopsy, were injected with
contrast medium. A control group was formed
from anterior descending coronary arteries free of
atherosclerosis and a study group from anterior
descending coronary arteries with areas of atherosclerotic
injury. The following differences in the
two groups were noted. The control group did not
show successfully injected vessels in intima and media,
while cases with atherosclerotic injury have
them; the number of injected vessels in presence
of atherosclerotic injury was three times greater
than in healthy coronary arteries; there was a decreasing
gradient from outside to in, in the number
of injected vessels in both groups; and finally in
atherosclerotic vessels we noted a lack of balance
between parietal thickening and the residual lumen
(conspicuous thickening was accompanied by a
small reduction in the lumen). We interpret centrifugal
thickening as a possible compensatory mechanism
in the major branches for an inadequate canalization
of vessel, and suggest possible formation
of coronary collateral circulation from vasa vasorum
by a process of neovascularization
Histological and ultrastructural description of benign adipocytic tumors in farmed striped sea bream (Lythognathus mormyrus)
No full textCutaneous neoplasms affecting wild striped bream (Lythognathus mormyrus) have been recorded after their introduction in a marine aquaculture farm in the Adriatic Sea. The tumors were evident on 24% of the reared fish, showing single or multiple nodules, with a diameter ranging between 0.5–4.0 cm. Histologically, all the neoplastic lesions were located in the stratum spongiosum of the dermis and were surrounded by a thin capsule of connective tissue. The tumors were predomi-nantly composed of adipocytes grouped and surrounded by a thin net of fibroblasts and collagen fibers. In some lipomas a mixture of adipocytes and uniform spindle cells were also observed. Fibroblasts and collagen fibers, or spindle cells, showing few mitotic figures were mainly observed in other nodules. Three of the tumors showed bands of cells with elongated nuclei. Five neoplasms differed from the classic spindle cell lipoma due to the presence of scattered giant cells. These cells presented acidophilic abundant cytoplasm with multiple hyperchromatic nuclei showing a concentric “floret-like” arrangement. The tumors were further characterized by ultrastructural observations that allowed ruling out the presence of virus-like particles within the lesions. Histological features of the masses lead to the identification of four prevalent patterns of neoplasms: lipoma, fibrolipoma, spindle cell lipoma (SCL), and atypical spindle cell-like lipoma (ASCL). The different neoplasms could arise from the transformation of mesenchymal cells of dermal origin. To the author’s knowledge, this is the first report describing key differential histological and ultrastructural features of these neoplasms in striped sea bream
NESIDIOBLASTOSIS ARISING FROM HETEROTOPIC PANCREAS AND PRESENTING WITH BLOOD HYPERTENSION
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Dermatoscopia de erythromelanosis folicular faciei et colli (Dermoscopy of Erythromelanosis Follicularis Faciei et Colli)
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