1,721,243 research outputs found
Obesità e funzione respiratoria negli studi di popolazione
No full textObesity and overweight are a major public health problem that causes nearly 3 million deaths worldwide each year. In addition to being an important risk factor for mortality and morbidity from cardiovascular disease, type 2 diabetes mellitus and cancer, obesity is associated with respiratory diseases with high epidemiological and clinical impact, such as bronchial asthma, COPD and obstructive sleep apnea syndrome. The effects of body weight and obesity on respiratory function have been also assessed in longitudinal studies on Italian population samples. In these studies it has been shown that BMI is a predictor of lung function along with age and height, BMI changes affect lung function decline, and reduction of body weight is associated with an increase in respiratory function. Moreover, there is increasing evidence that abdominal obesity in particular is involved, even through mechanisms of systemic infammation, with the impairment of respiratory function, which therefore might represent a link between cardiovascular risk factors and mortality
Erratum: Smooth reference equations for slow vital capacity and flow-volume curve indexes
No full textTrasferimento del monossido di carbonio ed invecchiamento
No full textIl fattore di trasferimento o capacità
di diffusione per il monossido di carbonio
(DLCO) misura l’abilità del polmone a trasferire
gas tra l’aria ambiente ed il sangue. Questa
misura è comunemente effettuata, in ambito sia
clinico sia epidemiologico, col metodo del
respiro singolo (DLCOsb). La misura della
DLCO è utile per l’inquadramento diagnostico
di patologie polmonari, in particolare quelle
che riducono l’area della superficie alveolare
e/o alterano il rapporto ventilazione/perfusione
nel polmone. Gli studi epidemiologici rappresentano
l’ambito ideale per descrivere il
comportamento della DLCO con l’invecchiamento,
ma pochi sono quelli in cui questo test
è stato eseguito; uno di questi è lo studio epidemiologico
prospettico condotto nell’area
rurale del delta del Po, Negli anni 1980-82 e
1988-91. L’analisi dei dati raccolti in questo
studio ha permesso di valutare, sia trasversalmente
sia longitudinalmente, il comportamento
dei parametri diffusivi nella popolazione generale
col variare dell’età, oltre che col variare di
misure antropometriche (altezza, BMI), sia in
condizioni fisiologiche sia in relazione alla presenza
di sintomi respiratori o fattori di rischio
come il fumo di sigaretta.The transfer factor or diffusing
capacity for carbon monoxide (DLCO) measures
the ability of the lung to transfer gas
between air and blood. This measure is usually
done, both in clinical setting and epidemiology,
by using the single breath method (DLCOsb) The
measurement of DLCO is useful for diagnosing
lung diseases, especially those which cause a
reduction of the alveolar surface and/or impair
the ventilation/perfusion ratio in the lung.
Epidemiological studies allow describing the
trend of DLCO with ageing, but this test has
been performed only in a few such studies; one
of these is the epidemiological prospective study
carried out in the rural area of Po river delta, during
1980-82 and 1988-91. The analyses of
the data collected in this study have permitted to
assess, both cross-sectionally and longitudinally,
the trend of diffusing parameters in the general
population with ageing, in addition to anthropometric
measurements (height, BMI), both in physiological
conditions and in relation to presence
of respiratory symptoms or risk factors, such as
cigarette smoking
Assessment of the relationship of CT findings with smoking history and pulmonary function tests results
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