169,804 research outputs found
Flammer syndrome: a response to the unknown aspects of acute inner ear troubles?
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Semicircular canal dehiscence: a possible direct cause of benign paroxysmal positional vertigo?
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Omega-3 fatty acids: a promising possible treatment for Meniere's disease and other inner ear disorders of unknown origin?
No full textA consolidated therapy for "idiopathic" acute disorders of the inner ear, including Meniere's Disease (MD), does not exist despite the long-lasting and widespread attempts: this lack is strictly linked to pathogenic uncertainties. According to the theoretical model that our group developed and tested over the years, a possible cause of labyrinthine damage could be identified in systemic hemodynamic changes followed by an abnormal peripheral vasoconstriction: the latter could be responsible for a more or less prolonged ischemia able to threaten a highly energy-requiring and complicated organ as the inner ear. A possible way to treat MD attacks - as well as other inner ear disorders that possibly share the same origin - according to our model should be addressed to modulate the peripheral circulation and to maintain the balance of ion exchange, acting both on systemic hemodynamics and on cell and organelle membranes. Despite the absence of such a proposal in the English literature, a reliable solution could derive from the supplementation of the intake of a nutritional principle as Omega-3 (omega-3) polyunsaturated fatty acids (PUFAs) that seem to theoretically fulfil all the requirements necessary to achieve a homeostasis of the inner ea
Early Management of Hearing and Balance Disorders. A Review of Literature and a Proposal to Overcome Possible Uncertainties.
No full textPulse-wave velocity and benign paroxysmal positional vertigo (BPPV)
No full textBackground: The aetiology of the BPPV is still uncertain. Some factors have been individualized that could explain partly the onset or the tendency to the recurrence, among which traumas, osteoporosis, viral infections and cardiovascular factors of risk. With particular reference to the influence that the cardiovascular factors of risk can practice on the genesis and persistence of the BPPV, it needs to keep in mind that, despite these introduces a role largely sustained in literature, it concerns considerations that hear again of very controversial interpretations however. Purpose: The objective of the study is to try to furnish a good definition of the existing relationship between the VPPB and the rigidity of the arterial tree, reliable expression of the conditions of the vascular circle and easily measurable with the appeal to recent technologies. Primary objective: the definition of possible differences of the profile of rigidity of the vascular system among subjects affections from BPPV and subjects without otologic diseases. Objective secondary: the definition of possible relationships between recidivist of BPPV and profile of vascular rigidity in a population of adults and elderly. Results: The results allow to affirm that an association exists among BPPV and increase of the arterial vascular rigidity, shown from the presence of more elevated values both of cfPWV (carotido-femoral Pulse Wave Velocity) that of differential arterial pressure or pulsatry pressure (PP) in the patients with BPPV in comparison to those measured in the healthy subjects of the same age. Moreover, an association exists between recurrence of the episodes of BPPV and increase of the arterial vascular rigidity in the patients of superior age to 60, shown by the presence of more elevated values of cfPWV in the patients with recurring BPPV in comparison to those measured in the subjects
A different modulation of vascular endothelial growth factor (VEGF) activation in response to hypoxia could cause different clinical pictures in the inner ear disorders.
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