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White superficial onychomycosis: epidemiological, clinical, and pathological study of 79 patients.
To analyze the epidemiology, responsible agents, clinical features, and outcome of white superficial onychomycosis (WSO).
Retrospective study.
University hospital.
A total of 79 patients with WSO seen at the Department of Dermatology of Bologna University from 1994 to 2002. Responsible agents included Trichophyton interdigitale in 58 cases (73%), Trichophyton rubrum in 4 (5%), Fusarium species in 9 (11%), Aspergillus species in 5 (6%), and Acremonium strictum in 3 (3%).
White superficial onychomycosis may have different clinical and epidemiological features. "Classic" WSO, characterized by superficial nail plate involvement, is usually due to Trichophyton mentagrophytes (var interdigitale), although Acremonium strictum or Onychocola canadiensis can sometimes be responsible. A deep and diffuse WSO, characterized by massive penetration of the nail plate by fungi, can be seen in nail infections by molds such as Fusarium species and Aspergillus species, or in nail infections by Trichophyton rubrum in healthy children and in patients infected with human immunodeficiency virus.
Severity and spread of WSO is the result of complex host-parasite relationships. When dealing with a patient with WSO, we should always consider the causative organism and the host characteristics to choose the best therapeutic approach
Trichoscopy. Illustrated atlas. Ediz. per la scuola
This book is a guide to the trichoscopic diagnosis of the most frequent hair diseases. Rich in photographs, it allows immediate visualization of the trichoscopic signs, useful for a comparison with the real aspects observed during clinical practice.
The pathogenesis of the various signs is indicated so that the reader is able to interpret the symptoms and the extent of the problem in the most appropriate way.
Contains indications on the correct magnifications for optimal visualization of the hair, skin and vessels; and the usefulness of dry or interface trichoscopy.
It is only with knowledge of the physiology and pathology of hair, and with practical experience, that one learns to diagnose and manage alopecia and trichoscopy helps in all three processes
Tricoscopia. Atlante illustrato. Ediz. illustrata
Questo libro è una guida alla diagnosi tricoscopica delle più frequenti malattie dei capelli. Ricco di fotografie, consente un’immediata visualizzazione dei segni tricoscopici, utile per un confronto con gli aspetti reali osservati durante la pratica clinica. Dei diversi segni è indicata la patogenesi affinché il lettore sia in grado di interpretare nel modo più opportuno i sintomi e l’entità del problema. Contiene indicazioni sugli ingrandimenti corretti per la visualizzazione ottimale dei capelli, della cute e dei vasi; e l’utilità della tricoscopia a secco o con interfaccia. È solo con la conoscenza della fisiologia e della patologia dei capelli, e con l’esperienza pratica, che si impara a diagnosticare e gestire le alopecie e la tricoscopia aiuta in tutti e tre i processi
Frontal Alopecia after Repeated Botulinum Toxin Type A Injections for Forehead Wrinkles: An Underestimated Entity?
BACKGROUND:
Injections of botulinum toxin type A in the forehead have never been reported to cause hair side effects.
OBJECTIVE:
The aim of this paper is to report a new type of alopecia, which we have seen in women undergoing periodic injections of botulinum toxin type A for forehead wrinkles, and to differentiate it from other types of hair loss.
METHODS:
We conducted an observational study on 5 females recruited from a private and an institutional practice who complained of progressive recession of the hairline after periodic injections of botulinum toxin type A in the forehead.
RESULTS:
Alopecia of the frontal hairline was evident in all 5 patients, with absence of skin atrophy or scarring and progressive hair miniaturization at trichoscopy.
CONCLUSION:
Dermatologists should be aware of the possible occurrence of frontal alopecia after repeated injections of botulinum toxin type A for forehead wrinkles.
KEYWORDS:
Alopecia; Botulinum toxin; Frontal alopecia; Wrinkle
Tinea Incognita following the Use of an Antipsoriatic Gel
Tinea incognita is a dermatophyte infection of the skin whose clinical presentation has been modified by the misuse of steroids or, as has been described recently, calcineurin inhibitors. We report a case of pustular psoriasis treated with an antipsoriatic cream, composed of topical steroids and a vitamin D3 derivative, which gave rise to a tinea incognita. Our case underlines that clinical features of fungal infection can be modified by the increasing use of self-prescribed topical therapies, usually applied to treat incorrectly 'self-diagnosed' diseases. Moreover, we suggest that a mycological examination should be performed in every atypical presentation of skin lesion, and to rule out tinea pedis, in any disease of the feet that requires topical application of steroids
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Androgenetic alopecia in children: report of 20 cases.
Androgenetic alopecia (AGA) is the most common type of hair loss in adults. Although there are differences in the age at onset, the disease starts after puberty when enough testosterone is available to be transformed into dihydrotestosterone. We report 20 prepubertal children with AGA, 12 girls and eight boys, age range 6-10 years, observed over the last 4 years. All had normal physical development. Clinical examination showed hair loss with thinning and widening of the central parting of the scalp, both in boys and girls. In eight cases frontal accentuation and breach of frontal hairline were also present. The clinical diagnosis was confirmed by pull test, trichogram and dermoscopy in all cases, and by scalp biopsy performed in six cases. There was a strong family history of AGA in all patients. The onset of AGA is not expected to be seen in prepubertal patients without abnormal androgen levels. A common feature observed in our series of children with AGA was a strong genetic predisposition to the disease. Although the pathogenesis remains speculative, endocrine evaluation and a strict follow-up are strongly recommended
Visualization of hair bulbs through the scalp: A trichoscopic feature of erosive pustular dermatitis of the scalp
Erosive pustular dermatitis of the scalp (EPDS) typically affects elderly people with scarring alopecia. Videodermoscopy (VD) of the scalp has never been assessed in the diagnosis of EPDS. To evaluate the trichoscopy features of EPDS, we carried out a retrospective analysis of VD images obtained in the scalp of ten patients who affected by EPDS and were compared with those obtained from a series of thirty patients who affected by other type of scarring alopecia. The most specific VD feature was thus represented by evident hair bulb in the scarring scalp, observed in all patients
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New fungal nail infections.
URPOSE OF REVIEW: The number of people affected by onychomycosis continues to increase. The prevalence of different pathogens in different areas depends on several factors, such as climate, geography and migration. We reviewed the recent literature to identify new agents responsible for onychomycosis. RECENT FINDINGS: Recent studies performed in different countries are not only reporting molds and yeasts as contaminants, but are increasingly reporting them as pathogens. Infection by novel agents is also being reported, although the individual cases do not necessarily indicate that these are emerging agents. SUMMARY: Clinicians should bear in mind the increased number of case series reporting the role of molds and yeasts in onychomycosis, and should not treat the disease without first examining the mycology results. The question remains as to whether these agents are truly new fungi responsible for onychomycosis, or whether improvement of diagnostic techniques and increasing reference to such species in the literature has resulted in better identification of such agents
Alopecia areata (AA) and treatment with simvastatin/ezetimibe: Experience of 20 patients
case series to evaluate the effectiveness of simvastatin/ezetimibe in patients with alopecia areat
Increasing new cases of mpox in Italy: From an epidemic infection to an endemic sexually transmitted disease?
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