1,354,856 research outputs found
As simbologias do pano de Pinti na etnia Mandjaku
No full textCOSTA, Adenauer Marcos da. As simbologias do pano de Pinti na etnia Mandjaku. 2017. 25 f. Projeto de pesquisa (Graduação) - Curso de Graduação em Humanidades. Instituto de Humanidades (IH), Universidade da Integração Internacional da Lusofonia Afro-Brasileira. Acarape-CE, 2018.Este trabalho tem como objetivo analisar os diferentes contextos do uso de pano de Pinti nos rituais fúnebres, casamentos e nos modos de vida da etnia Mandjaku parece-nos imprescindível trazer algumas abordagens históricas e contextuais, com intuito de oferecer ao leitor uma visão panorâmica do processo que pretendemos estudar, portanto, discutiremos na nossa fundamentação
teórica sobre organização da sociedade mandjuku, o declínio do reino de Basserel, reino de Caió, organização social e política dos mandjakus de Caió, a espiritualidade e divisão do trabalho na comunidade mandjaku, poder espiritual, por acharmos ser imprescindíveis para compreender o nosso objeto de estudo, por fim discutiremos sobre a origem do pano de pinti, seus usos e significados
F. Hectoris Pinti lusitani hieronymiani ... In diuinum vatem Danielem commentarii ...
No full textContiene: F. Hectoris Pinti ... In prophetae Ieremiae lamentationes commentarij (h. 244-303) ; F. Hectoris Pinti ... In diuinum vatem Nahum commentarij (25 [i.e. 36] h.)CCBE S. XVI,Mode of access: Internet.Marca tip. en ports.Colofón.Algunos ejemplares llevan port. para las "Lamentationes"Errores de fol., en primera secuencia de h. 271 pasa a la h. 273 y en segunda secuencia de h. 34 pasa a la h. 25.Texto a dos col.Sign.: [cristus]4, ?-3?6, 4?4, A-2O8, 2P6, [ ]2, 3A-3D8, 3E4
Could the periodontal therapy improve the cardiologic patient health? A narrative review
No full textBackground: Cardiovascular diseases (CVD) is the major cause of mortality globally, with increasing evidence suggesting a link between periodontitis, and CVD. This study aims to explore the association between periodontitis and CVD, and the impact of periodontal therapy on cardiovascular health. Methods: This review synthesized findings from preclinical and clinical studies, without publication year restrictions, examining periodontitis and CVD through various lenses. Scientific databases were inspected with keywords related to periodontitis and CVD. Results: The review identifies a substantial association between periodontitis and an increased risk of several CVD, supported by both epidemiological and interventional studies. Results suggest the complexity of the relationship, influenced by factors like the severity of periodontitis and the presence of other systemic conditions. Clinical data indicates that periodontal therapy, particularly non -surgical periodontal therapy, may reduce systemic inflammatory markers and thus may play a role in the primary and secondary prevention of CVD events, highlighting the potential of periodontal therapy to not only maintain oral health but also to modulate cardiovascular risk factors. Conclusions: Current evidence supports a significant association between periodontitis and increased cardiovascular risk, promoting integrated healthcare approaches that consider oral health as a key -component of cardiovascular care and wellbeing
A Methodological Framework to Optimize Data Management Costs and the Hand-Over Phase in Cultural Heritage Projects
No full textThis paper illustrates a methodological approach to optimize the data management process and to reduce costs related to information loss, from the preliminary phases to the Facility Management (FM) one. The growing concern about sustainability issues has steadily increased attention to cultural heritage’s key role. Concurrently, Europe promotes the application of digital methods for managing interventions both for new and existing buildings. The data issue, especially in heritage projects, represents a crucial aspect; data-recovering activities or shortages of information contribute to relevant expenses and discourage stakeholders. The research focuses on how procedures involving digitalization, applied to heritage projects, can improve the information workflow, supporting the hand-over stage. Although the application of digital techniques has recognized advantages, enhancements for optimizing time and cost savings are required. The research result is a methodological framework to obtain complete heritage as-built deliverables for the management phase. The defined structure is applied through a case study approach to the restoration of a historical lyric theater. Thus, the as-built model represents a database for controlling costs and maintenance procedures. In the end, the work provides a tangible contribution to the Heritage BIM (HBIM) delivery and can be a starting point for future improvements
Aeroacoustic Reduced-Order Models Based on a priori/posteriori Data Analysis
No full textTwo Reduced-Order Models for the simulation of aeroacoustic phenomena are presented.
One model is based on Proper Orthogonal Decomposition, relying on a posteriori analysis of
a set of high-delity calculations, the snapshots in the parametric space. To partially reduce
the number of necessary snapshots, a self-adaptive sampling technique is proposed. Instead
of a regular and homogeneous one-step sampling, a gradual and optimised enhancement of
the sample set is dened. The second model is based on Proper Generalized Decomposition,
which can be viewed as a a-priori approach, able to build the reduced-order approximation
without relying on the knowledge of the solution of the complete problem, assessing the
model accuracy and, if necessary, to enrich the reduced approximation basis. Both methods
are applied to the computation of scattering of sound by a circular cylinder
Sviluppo e test di sistemi, algoritmi e metodi per la validazione di smart object in applicazioni illuminotecniche e ambient assisted living
No full textLa presente tesi si focalizza sullo sviluppo di soluzioni innovative IoT attraverso Smart Object, finalizzati a rendere l'ambiente circostante intelligente.
Il progetto di ricerca ha l’obbiettivo di proporre una soluzione completa in grado di rendere più efficienti i sistemi innovativi in ambito industriale e domestico. I dati raccolti attraverso l’impiego di sensori, in grado di misurare le grandezze di interesse, hanno generato dei feedback che migliorano da una parte i processi produttivi e dall’altra il monitoraggio dello stato di salute di un soggetto, automatizzando azione correttive.
Nello specifico ci si è concentrati su due ambiti: la valutazione dell'affidabilità dei diodi ad emissione di luce (LED) per lo sviluppo di sistemi Smart Lighting ad alte prestazioni e lo sviluppo di sistemi innovativi per l’Ambient Assisted Living e Smart Living, con focus sul tema dell’invecchiamento e sulla misurazione dell’Età Biologica (BA) tramite sensori inerziali.
Per quanto riguarda il primo ambito l’attività di ricerca ha riguardato la definizione di protocolli sperimentali finalizzati alla valutazione dell'affidabilità e del tempo di vita dei LED impiegati nella realizzazione di sistemi Smart Lighting ad alte prestazioni. Attività sempre più importante negli attuali sistemi illuminotecnici finalizzati, non solo a fornire illuminazione, ma anche a far parte di sistemi di Smart Environment attraverso cui somministrare nuovi servizi. In particolare, le ricerche sono state concentrate sull’affidabilità del giunto di saldatura che, in seguito alla comparsa di fessure (cracks) e bolle (voids), è il fattore principale che influenza il tempo di vita di un sistema di illuminazione.
Per quanto riguarda il secondo ambito applicativo si è sviluppato un sistema di sensori indossabili, che è in grado di monitorare l'attività motoria, rilevando eventuali problemi nell'analisi del cammino e nella stabilità posturale. Dai risultati ottenuti nelle prove effettuate sul campo, il sistema assicura prestazioni analoghe rispetto al gold standard del settore. Visto gli ottimi risultati ottenuti dai dispositivi, questi possono essere utilizzati per il monitoraggio continuo dell'anziano al di fuori dell'ambiente ospedaliero in modo da realizzare sistemi Smart Health, sistemi di telecontrollo e telemonitoraggio.This thesis focuses on the development of innovative IoT solutions through Smart Objects, with the aim of making surrounding environment intelligent.The research project aims to propose a complete solution capable of making innovative systems in the industrial and domestic sectors more efficient. The data collected through the use of sensors, capable of measuring the quantities of interest, generated feedback that improves the production processes on the one hand and the monitoring of the health of a subject on the other, automating corrective action.
Specifically, we focused on two areas: the assessment of the reliability of light emitting diodes (LEDs) for the development of high performance Smart Lighting systems and the development of innovative systems for Ambient Assisted Living and Smart Living, with a focus on the topic of aging and on the measurement of Biological Age (BA) through inertial sensors.
With regard to the first area, the research activity concerned the definition of experimental protocols aimed at assessing the reliability and lifetime of the LEDs used in the construction of high-performance Smart Lighting systems. An increasingly important activity in current lighting systems aimed not only at providing lighting, but also at being part of Smart Environment systems through which to administer new services. In particular, research has been focused on the reliability of the solder joint which, following the appearance of cracks and bubbles (voids), is the main factor affecting the lifetime of a lighting system.
As regards the second application area, a wearable sensor system has been developed, which is able to monitor motor activity, detecting any problems in gait analysis and postural stability. From the results obtained in the tests carried out in the field, the system ensures similar performance compared to the gold standard of the sector. Given the excellent results obtained by the devices, these can be used for the continuous monitoring of the elderly outside the hospital environment in order to create Smart Health systems, remote control systems and remote monitoring
A dataset for wearable sensors validation in gait analysis
No full textThe article describes a dataset of gait measures acquired to validate the use of wearable sensors in gait analysis since its measurements can be compared with those provided by the stereophotogrammetric system. The comparison with a gold standard in gait analysis makes the dataset useful for the development, testing and validation of algorithms for estimating gait parameters. The dataset contains measurements simultaneously acquired by the wearable sensors and the stereophotogrammetric system during an acquisition campaign performed on 5 healthy subjects (2 females and 3 males aged between 25 and 35 years). In the acquisition campaign the involved subjects carried out a motion task wearing the wearable sensors and reflective markers of the stereophotogrammetric system. In particular, the subjects wore in each foot a wearable sensor on the instep and a reflective marker on heel, first metatarsal head, fifth metatarsal head, and above the sensor, respectively. During the motion task each subject walked over an 11-meter long walkway according to its own course. The 5 subjects involved in the acquisition campaign performed 3 repetitions of the motion task, for a total of 15 trials in where the measures collected by wearable sensors and the stereophotogrammetric system can be compared
Small RNAs in prokaryotes and eukaryotes: A lesson for human immunologists: Comment on "Diversity, evolution, and therapeutic applications of small RNAs in prokaryotic and eukaryotic immune systems" by Edwin L. Cooper and Nicola Overstreet.
No full textNo abstract availabl
Hydrogen sulfide metabolism in cancer and homocystinuria: towards the development of new pharmacological strategies
No full textHydrogen sulfide (H2S), along with nitric oxide (NO) and carbon monoxide (CO), belongs to a small group of gaseous signalling molecules termed ‘gasotransmitters’. H2S is involved in important physiological and pathological processes and exerts a dose-dependent effect on cellular bioenergetics, acting at higher levels as an inhibitor of mitochondrial cytochrome c oxidase or stimulating ATP synthesis at lower concentrations. A growing number of pathologies are reportedly associated with alterations of H2S metabolism. Here, the human H2S metabolism was investigated in classical homocystinuria and in cancer; furthermore, it was explored a new pharmacological strategy against cancer based on human ferritin (Hft) as a drug delivery system. Classical homocystinuria is a rare genetic disease, associated with mutations in the gene encoding the heme-containing enzyme cystathionine β-synthase (CBS), a major source of H2S in humans. CBS is allosterically activated by S-adenosyl-L-methionine, but inhibited by CO or NO. Here, it was found that the pathogenic p.P49L variant of human CBS, as produced in E. coli and purified, displays reduced affinity for the PLP (pyridoxal 5’-phosphate) cofactor and increased affinity of the ferrous heme for CO. This could lead to enzyme inhibition at physiological CO concentrations, thereof representing a pathogenic mechanism in classical homocystinuria. Hydrogen sulfide plays an important role also in colon cancer where it promotes angiogenesis and, interestingly, energy metabolism. Here, the H2S catabolism was explored in colon cancer model cells (SW480) exposed to hypoxia, a common factor of tumoral microenvironment that promotes tumor cell survival and propagation. Cells were grown under either normoxic (20% O2) or hypoxic (1% O2) conditions and their ability to metabolize H2S at the mitochondrial level was assayed by high resolution respirometry. Intriguingly, exposure to hypoxic conditions for 24 hours, while reducing the mitochondrial mass and the maximal efficacy to metabolize sulfide, was found to increase the expression of the H2S-metabolizing mitochondrial enzyme sulfide:quinone oxidoreductase. These effects induced by hypoxia may affect the H2S levels in SW480 cells, pointing to H2S catabolism as a potential drug target in colon cancer. Finally, in order to design new therapeutic strategies against cancer, it was obtained an engineered human ferritin-based nanocarrier (HFt-MP-PASE), able to effectively incorporate and deliver the chemotherapeutic drug mitoxantrone with high killing efficacy against model cells of colon cancer progression (SW480 and SW620)
Letter: Does obesity affect the severity of exercise-induced muscle injury? (j obes metab syndr 2021;30:132-40)
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