1,721,051 research outputs found
Prognostic Role of Cardiac Magnetic Resonance Imaging in Patients with Previous Myocardial Infarction: A Clinical Dataset
Q-wave prediction of myocardial infarct location, size and transmural extent at magnetic resonance imaging
We investigated how pathologic Q waves or equivalents predict location, size and transmural extent of myocardial infarction (MI)
Automatic Assessment of Myocardial Fibrosis by Delayed Enhanced Magnetic Resonance Imaging
Health-Related Quality of Life in Italian Adolescents During Covid-19 Outbreak
Coronavirus disease 2019 (COVID-19) outbreak represented an experience of social isolation potentially leading to changes in the health quality of life. The aim of this study is to investigate the health-related quality of life during quarantine in early adolescents. Data were collected from 1,289 adolescents (mean age, 12.5; male, 622), at the beginning of the school year (September 2019, Standard Condition, SC) as part of the AVATAR project and during Phase 1 of the Italian lockdown (mid-late April 2020) (COVID-19 Quarantine, CQ) using an online questionnaire. In the CQ period, with respect to SC, adolescents showed lower perception in the dimensions, such as psychological (p = 0.001), physical well-being (p = 0.001), mood/emotion (p = 0.008), autonomy (p = 0.001), and financial resources (p = 0.018). Relationship with the family (p = 0.021) and peers (p = 0.001), as well as the perception of bullying (p = 0.001) were reduced. In lifestyle, adolescents developed higher adherence to the Mediterranean diet (p = 0.001). Adolescents living in the village had greater reduction in both autonomy (p = 0.002) and peer relationships (p = 0.002). Moreover, the perception of physical well-being was lower in those living in the city instead of those living in the countryside (p = 0.03), in an apartment instead of a detached house (p = 0.002), and in those who did not have green space (p = 0.001). Gender effect emerged for the psychological (p = 0.007) and physical well-being (p = 0.001), mood/emotion (p = 0.001), and self-perception (p = 0.001). The study showed that health-related quality of life during quarantine changed in its psychosocial dimensions, from mood and self-esteem to social relationships, helping to define the educational policies at multiple points in the promotion process of health
The impact of menarche on health-related quality of life in a sample of Italian adolescents: evidence from school-based AVATAR project
Adolescence is a period characterized by rapid physical maturation, involving bodily changes that often necessitate a reorganization of self-perception. The current study investigated the impact of menarche on the determinants of quality of life in healthy female adolescents. Data were collected from 361 healthy female adolescents divided into two groups: pre- and post-menarcheal event. Participants, according the AVATAR project, completed Italian version of KIDSCREEN-52 questionnaires on health-related quality of life. Pre-menarcheal females had the higher score in psychological well-being and mood than post-menarcheal females. As concerns self-perception, post-menarcheal females exhibited lower score compared to pre-menarcheal females. In social context, pre-menarcheal females perceived a better school environment, also when we considered it in terms of social acceptance.Conclusion: Menarche event affects all the components of quality of life, from mood, self-esteem to social relationships, underlining how this hormonal variation is responsible of psychological and emotional changes, opening up the opportunity for preventive approaches aimed not only at traditional risk factors but according a more integrated perspective.What is Known:• Adolescence is a time of increasing behavioural divergence between males and females, probably due to the different hormonal development.• There is a possible link between menarche and the health-related quality of life variables.What is New:• Menarche condition affects all the components of quality of life, from mood to social relationships.• Post-menarcheal condition is associated to psychosocial and emotional changes, with possible multiple pathways to post-pubertal depressive symptoms
A fast and effective method of quantifying myocardial perfusion by magnetic resonance imaging
The quantification of global myocardial blood flow (MBF) by measuring coronary sinus flow by magnetic resonance (MRI) was demonstrated to be very well correlated with positron emission tomography (PET). We proposed a new method for the quantification of regional myocardial perfusion with MRI by the integration of MBF and first pass technique. The aim of this study was to validate this new method for quantification of regional perfusion by comparing it with 13NH13-PET in swine models of myocardial infarction and in humans in resting and hyperemic conditions. MRI and 13NH3-PET was performed in 2 healthy swine, 11 swine models of myocardial infarction (5 reperfused, 6 non reperfused) and in 12 humans at rest and during hyperemia. MBF was estimated by MRI through the quantification of coronary sinus flow and left ventricular (LV) mass. The upslope of signal intensity (SI-upslope) of each myocardial segment was obtained by the first pass gadolinium technique. Regional SI-upslope was indexed by the upslope of the entire left ventricular myocardium (global upslope). Regional myocardial perfusion was estimated as the product of MBF and SI-upslope/global upslope. Regional perfusion was also estimated by 13NH3-PET. A close agreement of the MRI and PET techniques for measurement of regional myocardial perfusion was found in all myocardial segments by Bland-Altman analysis (mean difference 5.1 %; limits of agreement, -37.2-27.5 %). With the integration of the first pass technique and the measurement of global MBF by coronary sinus flow/LV mass, MRI allows direct quantification of regional myocardial perfusion
Sweat Rate Monitoring During Maximal Exercise in Healthy Soccer Players: A Close Relationship with Anaerobic Threshold
Purpose: Sweating is a homeostatic phenomenon regulated by both thermal and non-thermal factors during exercise. There are no evidences whether anaerobic metabolism induced during isotonic maximal exercise can modify sweating rate. Aim of the study was to investigate the relationship between sweating and the anaerobic
threshold (AT).
Methods: The sweat rate in thirteen soccer players was measured by a sensor providing a continuous monitoring of sweating, whereas the anaerobic threshold was assessed with ergospirometry during maximal isotonic stress test. During stress test, cardio respiratory, metabolic and galvanic skin response (GSR) were also monitored.
Results: At AT, stroke volume, heart rate and systolic blood pressure significantly increased (p<0.001), as well as GSR (p=0.04). Sweat rate abruptly increased at AT compared with rest (p<0.001). AT-to-rest changes in sweating rate were associated with concomitant changes in VO2 max (r=0.82, p<0.001), heart rate (r=0.73, p=0.04) and GSR (r=0.79, p=0.001).
Conclusion: We suggest that aerobic-to-anaerobic switch is associated with a sudden increase in sweating likely induced by sympathetic activation. Considering the role of hydration in preserving the health status and optimizing the physical performance, we believe that this finding may have relevant practical implication in particular in soccer, which is characterized by an alternation of aerobic and anaerobic phases
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