17,282 research outputs found
First-trimester placental volume and vascularization measured by 3-dimensional power Doppler sonography in pregnancies with low serum pregnancy-associated plasma protein a levels
No full textPlacental volume and uterine artery doppler evaluation at 11 + 0 to 13 + 6 weeks of gestation in pregnancies conceived with in vitro fertilization: comparison between autologous and donor oocyte recipients
No full textOBJECTIVE:To compare uterine artery pulsatility index (PI) and three dimensional(3D) placental volume values in first trimester pregnancies conceived naturally or through in-vitro fertilization (IVF) technique using either autologous or donor oocytes and to relate these measurements with pre-eclampsia (PE) development.
METHODS:
Uterine artery PI and placental volume were measured in 416 IVF pregnancies (307 women with autologous and 109 with donor oocytes) and in 498 spontaneously conceived pregnancies at 11 + 0-13 + 6 weeks of gestation. We recruited nulliparous women with singleton pregnancies. The measured mean uterine artery PI and placental volume values were converted to multiples of the expected normal median (MoM) adjusted for gestational age. MoM values of IVF pregnancies were compared with the naturally conceived group and related to PE development.
RESULTS:
No differences were found in uterine artery PI MoM between groups. Placental volume was significantly reduced in IVF pregnancies (K =169.3; p≤0.0001). Among IVF pregnancies significantly lower placental volume values were found in the donor oocytes recipients when compared to the autologous subgroup (z=3.89: p < 0.001). In IVF pregnancies developing PE lower values of placental volume were evidenced with respect to the normotensive ones (donor oocytes U=6.8; p = 0.009; autologous oocytes U = 5.1; p = 0.023) while no differences were found for uterine artery PI values. Multivariate logistic regression analysis demonstrated that placental volume is an independent predictor of PE (OR 1.97 (1.33-2.27)) as well as donor IVF (OR 2.24 (1.5-2.83)), while autologus IVF does not result significant in the model.
CONCLUSIONS:
First-trimester placental volume, as assessed by 3D ultrasound, is reduced in IVF pregnancies and this reduction is more marked in donor oocytes recipients. The relative decrease of placental volume found in IVF pregnancies that developed PE suggests an etiological mechanism different from uterine perfusion in such patients
CARDIOVASCULAR CHANGES IN AORTIC ISTHMUS AND DUCTUS VENOSUS IN GROWTH RESTRICTED FETUSES
No full textFirst-trimester umbilical vein blood flow in pregnancies with low serum pregnancy-associated plasma protein-A levels: an early predictor of fetal growth restriction
No full textEffects of maternal cigarette smoking on placental volume and vascularization measured by 3-dimensional power Doppler ultrasonography at 11+0 to 13+6 weeks of gestation
No full textThe significance of visualising coronary blood flow in early onset severe growth restricted fetuses with reverse flow in the ductus venosus
No full textRole of sonographic automatic volume calculation in measuring fetal cardiac ventricular volumes using 4-dimensional sonography: comparison with virtual organ computer-aided analysis
No full textAre There Differences in Placental Volume and Uterine Artery Doppler in Pregnancies Resulting From the Transfer of Fresh Versus Frozen-Thawed Embryos Through In Vitro Fertilization?
No full textOBJECTIVES: To compare uterine artery pulsatility index (PI) and 3-dimensional (3D) placental volume values in first-trimester pregnancies conceived naturally or through in vitro fertilization (IVF) technique using either fresh or cryopreserved embryo and to relate these measurements with preeclampsia (PE) development.
METHODS:
Uterine artery PI and placental volume were measured at 11 + 0 to 13 + 6 weeks of gestation in 266 IVF pregnancies (139 women with fresh embryo and 127 women with frozen-thawed embryo transfer) and in 266 spontaneously conceived pregnancies matched for maternal age. Nulliparous women with singleton pregnancies were recruited. The mean, highest, and lowest uterine artery PI and placental volume values measured were converted to multiples of the expected normal median (MoM) adjusted for gestational age. The MoM values of IVF pregnancies were compared with those of the naturally conceived group and related to PE development.
RESULTS:
No differences were found in uterine artery PI MoM between the 3 groups. Placental volume was significantly lower than in both IVF groups when compared to the controls (fresh embryo IVF Z = 9.33; P ≤ .0001; frozen-thawed embryos IVF Z = 3.1; P = .04). The IVF pregnancies with fresh embryos showed placental volume MoM values significantly lower than in the frozen-thawed embryo IVF pregnancies (U = 5.4; P ≤ .0001). In fresh embryo IVF pregnancies developing PE placental volume values resulted lower than in the normotensive ones (U = 2.11; P = .03), while no differences were found for uterine artery PI values.
CONCLUSION:
First-trimester placental volume, as assessed by 3D ultrasound, is reduced in IVF pregnancies, and these differences are more marked in those obtained with fresh embryos than those obtained with cryopreservation. This may explain the better obstetrical and perinatal outcomes occurring with the former technique
Assessment of corpus callosum biometric measurements at 18 to 32 weeks' gestation by 3-dimensional sonography
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