4,563 research outputs found
The SSC of the Generalised Jahangir’s Graph Jm,k and its Algebraic Characterizations
In this article, we present important combinatorial and algebraicproperties of spanning simplicial complex (SSC) of the generalised Jahangir’sgraph Jm,k. We describe the relation to find f−vectors associatedto Δs(Jm,k) and determine the Hilbert series for the SR-ring KΔs(Jm,k).In the end, we present the associated primes of the facet ideal IF(Δs(Jm,k))and the Cohen-Macaulay characterization of the SR-ring of Δs(Jm,k).AMS (MOS) Subject Classification Codes: Primary 13-P10, Secondary 13-F20, 13-C14, 13-H10.Corresponding Author: Agha KashifKey Words: Simplicial Complexes, f-vectors, Spanning Trees, Face Ring, Hilbert Series, CohenMacaulay
To <i>JM</i> on Its 75th Anniversary
This article discusses how Journal of Marketing ( JM) has influenced marketing science and practice by publishing articles on substantive topics relevant to customers, managers, organizations, markets, and society. The journal's 75th anniversary coincides with the 50th anniversary of the Marketing Science Institute (MSI). Frequently, JM and MSI have collaborated to address important substantive marketing issues identified in MSI's Research Priorities. The author highlights seminal articles on brand equity; business-to-business marketing (including sales force management); connecting marketing information, metrics, and strategy; consumer behavior; innovation, new product development. and product management; marketing orientation and capabilities; and market research, methodology and services. She also draws attention to articles that have won the Sheth Foundation/ JM Award and the H. Paul Root Award. The article describes how JM‘s knowledge dissemination is amplified by powerful social network effects. Ideas in JM articles diffuse through the business community, influencing the mind-set of managers worldwide. </jats:p
Efficacy of Assistive Devices Produced with Additive Manufacturing
Despite the frequency of musculoskeletal injuries such as sprains, broken bones and torn ligaments1, treatment options are often costly, time-consuming and ill-fitted.2,3 Additive manufacturing (“3D-printing) allows for the production of highly-customized and inexpensive assistive devices4, which suggests potential efficacy in the prescription of splints and casts for musculoskeletal injury.3 In the present study, a parametric, customizable splint/cast was created using a computer-aided design (CAD) package (Fusion 360, Autodesk, San Rafael, CA, USA) and produced with low-cost, desktop 3D printing (Ultimaker 2+ Extended, Ultimaker, Geldermalsen, Netherlands). Fitting of the devices was performed on five healthy subjects (mean age 23.6 +/- 1.51 years, n = 4 male), and function was assessed by a certified clinician in comparison to commonly prescribed devices. The function of the custom, 3D-printed assistive devices was found to be similar to that of standard wrist splints and short arm casts, with the added benefits of reduced weight, enhanced water resistance and better ventilation. These results suggest that additive manufacturing may be promising in the treatment of common musculoskeletal injuries. Holder NL, Clark HA, DiBlasio JM, Hughes CL, Scherpf JW, Harding L & Shepard KF, Physical therapy, 79(7), 642-652, 1999. Dombroski CE, Balsdon ME, & Froats A, BMC research notes, 7(1), 443, 2014. Kim H & Jeong S, Journal of mechanical science and technology, 29(12), 5151-5156, 2015 Zuniga JM, Peck JL, Srivastava R, Pierce JE, Dudley DR, Than NA & Stergiou N, Disability and Rehabilitation: Assistive Technology, 1-7, 2017
Gridded Shapefile for the Recharge Zones of the Barton Springs segment of the Edwards Aquifer
<p>General Information:</p>
<p>This is a GIS shapefile that delineates hydraulic conductivity and recharge zones for the Barton Springs segment of the Edwards Aquifer in central Texas, USA. The groundwater system is a karstic aquifer in a rapidly urbanizing portion of the City of Austin. The shapefile boundary aligns with a numerical groundwater simulation of the aquifer system with cells matching the active regions of the MODFLOW model. Zonation reflects 11 areas that are useful for integrated groundwater management and modelling.</p>
<p>Use cases and further information:</p>
<p>A numerical simulation (MODFLOW model) was developed for use as a groundwater availability model (GAM) in the State of Texas (Scanlon et al, 2003; Scanlon et al, 2001). The recharge zones were developed for Barton Springs GAM because it represents a baseline interpretation of groundwater behavior, the model is readily accessible. Zonation was originally completed so that a systems dynamics model of urban and land use conditions overlying the aquifer could be connected to a systems dynamics model as part of a Groundwater Decision Support System developed to assess the sustainable yield (Pierce et al, 2006; Pierce, 2006). The recharge zone files can be used to compare the decision relevance of scientific uncertainty by comparing groundwater response to variable pumping regimes across different recharge interpretations (Passarello et al, 2014; Passarello et al, 2012).</p>
<p>Cited References:</p>
<p>Passarello, MC, Pierce SA, Sharp, JM, 2014, Uncertainty and urban water recharge for managing groundwater availability using decision support, Water Science & Technology Journal, 70(11), doi:10.2166/wst.2014.437.</p>
<p>Passarello, M., Pierce, S.A., Sharp, JM, 2012, Estimating Urban-Induced Artificial Recharge A Case Study for Austin, Texas, Environmental and Engineering Geoscience, 18 (1), p. 25-36.</p>
<p>Pierce, S.A., Dulay, M.M., Sharp, J.M., Lowry, T.S., Tidwell, V.C., 2006, Defining tenable groundwater management: Integrating stakeholder preferences, distributed parameter models, and systems dynamics to aid groundwater resource allocation. MODFLOW and More. International Groundwater Modeling Center, Golden, Colorado.</p>
<p>Pierce, S.A., 2006, Groundwater Decision Support: An integrated assessment linking causal narratives, numerical models, and combinatorial search techniques to determine available yield for an aquifer system, PhD thesis, Jackson School of Geosciences, Department of Geology, The University of Texas at Austin</p>
<p>Scanlon, B.R., Mace, R.E., Barrett, M.E., Smith, B., 2003, Can we simulate regional groundwater flow in a karst system using equivalent porous media models? Case Study, Barton Springs Edwards aquifer, USA, Journal of Hydrology, v. 276, p. 137 – 158.</p>
<p>Scanlon, B.R., Mace, R.E., Smith, B.A., Hovorka, S.D., Dutton, A.R., Reedy, R.C., 2001, Groundwater Availability of the Barton Springs Segment of the Edwards Aquifer, Texas – Numerical Simulations through 2050: The University of Texas at Austin, Bureau of Economic Geology, final report prepared for the Lower Colorado River Authority, under contract no. UTA99-0</p
JM-20, a Benzodiazepine-Dihydropyridine Hybrid Molecule, Inhibits the Formation of Alpha-Synuclein-Aggregated Species
\ua9 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.Studies showed that JM-20, a benzodiazepine-dihydropyridine hybrid molecule, protects against rotenone and 6-hydroxydopamine neurotoxicity. However, its protective effects against cytotoxicity induced by endogenous neurotoxins involved in Parkinson’s disease (PD) pathogenesis have never been investigated. In this study, we evaluated the ability of JM-20 to inhibit alpha-synuclein (aSyn) aggregation. We also evaluated the interactions of JM-20 with aSyn by molecular docking and molecular dynamics and assessed the protective effect of JM-20 against aminochrome cytotoxicity. We demonstrated that JM-20 induced the formation of heterogeneous amyloid fibrils, which were innocuous to primary cultures of mesencephalic cells. Moreover, JM-20 reduced the average size of aSyn positive inclusions in H4 cells transfected with SynT wild-type and synphilin-1-V5, but not in HEK cells transfected with synphilin-1-GFP. In silico studies showed the interaction between JM-20 and the aSyn-binding site. Additionally, we showed that JM-20 protects SH-SY5Y cells against aminochrome cytotoxicity. These results reinforce the potential of JM-20 as a neuroprotective compound for PD and suggest aSyn as a molecular target for JM-20
Uterine transplantation: a promising surrogate to surrogacy?
Uterine transplantation: a promising surrogate to surrogacy?
Grynberg M1, Ayoubi JM, Bulletti C, Frydman R, Fanchin R.
Author information
Abstract
Infertility due to the inability of the uterus to carry a pregnancy ranks among the most unresolved issues in reproductive medicine. It affects millions of women worldwide who have congenital or acquired uterine affections, often requiring hysterectomy, and potentially represents a considerable fraction of the general infertile population. Patients suffering from severe uterine infertility are currently compelled to go through gestational surrogacy or adoption; both approaches, unfortunately, deprive them of the maternal experience of pregnancy and birth. Uterine transplantation represents an outstanding, yet complex, perspective to alleviating definitive uterine infertility. In the past decades, a number of scientific experiments conducted both in animals and women, focusing on uterine transplantation, have led to promising results. Collectively, these findings undoubtedly constitute a sound basis to clinically apply uterine transplantation in the near future. This paper is, however, an overview not only of the extent and limitations of accumulated scientific knowledge on uterine transplantation, but also its ethical implications, in an effort to define the actual place of such an approach among the therapeutic arsenal for alleviating infertility.
© 2011 New York Academy of Sciences
Translation and interpretation: Translation redundancy reconsidered
Interpretation is an integral part of the process of translating. This article raises the question of whether interpretation fo a literary work by a translator should be guided by extratextual factors or not. The discussion is illustrated with examples taken from David Hawkes' translation of a Chinese classic, A Dream of Red Mansions. As the work of a scholar-translator, Hawkes' version is richly supplemented with disclosures concerning the characters and explanations of the cultural environment embodied in the novel. In many cases, however, this translation procedure is redundant and explanatory, enlightening the readers but at the same time robbing them of the pleasure of literary interpretation and cultural exploration. By means of this illustration of translation redundancy, the author points out that there is difference between a scholar who helps the interpretation fo a work and a translator who presents a work close to its original version. It is particularly important to pay attention tot his difference in literary translations in a cross-cultural situation involving two enormously different cultures.Language & LinguisticsA&HCI0ARTICLE1,SI115-12
INTERNATIONAL FINANCIAL REPORTING STANDARDS (IFRS), BAIK BAGI USAHA MIKRO KECIL MENENGAH? (Studi Kasus: UMKM JM KERIPIK)
ABSTRAKUndang-undang nomor 20 tahun 2008 tentang Usaha Makro Kecil Menengah (UMKM), usaha kecil adalah usaha ekonomi produktif yang berdiri sendiri, yang dilakukan oleh orang perseorangan atau badan usaha yang bukan merupakan anak perusahaan atau bukan cabang perusahaan yang memiliki, dikuasai atau menjadi bagian baik langsung maupun tidak langsung dari usaha menengah atau usaha besar yang memenuhi kriteria. JM Keripik merupakan salah salah UMKM yang bergelut dibidang produksi dan penjualan. IFRS merupakan seperangkat standard yang dikeluarkan oleh Dewan Standard Akuntansi Internasional (IASB). IFRS berguna untuk menyusun laporan keuangan yang dapat diterima di dunia Global.Penulistertarik untukmengetahuipencatatankeuanganJM Keripik dan apakah perlu merekomendasikan IFRS pada UMKM JM Keripik. Metode penelitian yang digunakaan penulis adalah kualitatif yaitu observasi dan wawancara. Dari hasil penelitian banyak terdapat pencatatan-pencatatan yang kurang terperinci, UMKM JM Keripik hanya memilki empat macam pencatatan yaitu pencatatan mengenai: 1.Stock barang, 2.Supliyer, 3.Costumer dan 4.Stock toko, pencatatan ini hanya dapat dimengerti oleh pemilik JM Keripik. Sebaiknya pemilik UMKM JM Keripik mengganti laporan keuangan yang sederhana ke laporan keuangan yang semestinya dan yang berbasis IFRS karena IFRS membawa dampak positif bagi UMKM dan merupakan standar akuntansi keuangan yang digunakan dunia global. Kata Kunci : UMKM, IFRS, JM Keripik ABSTRACT Act number 20 of 2008 concerning the Macro Small and Medium Enterprises, small businesses are productive economic activities that stand alone, carried out by an individual or business entity that is not a subsidiary or not a branch of the company that owns, controlled or become part either directly or indirectly from medium or large businesses that meet the criteria. JM Keripik which deals in the field of production and sales. IFRS is a set of standards issued by the International Accounting Standards Board (IASB). IFRS is useful for preparing financial statements that is acceptable in the global world. Authors interested in knowing the financial records of JM Keripik and whether to recommend IFRS on JM Keripik. The research method is qualitative author of observation and interviews. From the research there are many registries are less detailed, JM Keripik has only four kinds of recording is recording about: 1.Stock goods, 2.Supliyer, 3.Costumer and 4.Stock shop, registration can only be understood by the owner of JM Keripik. JM Keripik owners should replace the simple financial reports to the appropriate financial statements and IFRS-based IFRS for Macro Small and Medium Enterprises had a positive impact and a financial accounting standards global world. Keywords : UMKM, IFRS, JM Keripi
Gridlock: chaos and confusion in our prisons
Behind the headlines and political posturing, the prison system is in crisis, with inhumane conditions and overcrowding making a mockery of justice, argues Peter JM Wayne, who has spent over 20 years inside. Copyright (c) 2008 The Author. Journal compilation (c) 2008 ippr.
Company „JM SLAT” internal and external environmental analysis and future perspective.
Bakalaura darba tēma ir „Uzņēmuma SIA „JM SLAT” ārējās un iekšējās vides analīze”. Izpētāmais uzņēmums „JM Slat” ir dibināts 2003.g. Varakļānu novadā un tā pamatdarbība ir kokapstrāde.
Bakalaura darba mērķis ir balstoties uz teorētiskajiem aspektiem izpētīt, izanalizēt SIA „JM SLAT” uzņēmuma iekšējās un ārējās vides struktūru, noteikt uzņēmuma nākotnes perspektīvas, noteikt stiprās un vājās puses, izdarīt secinājumus un priekšlikumus par uzņēmuma attīstība iespējām.
Lai sasniegtu bakalaura darba mērķus, ir nepieciešams noskaidrot iekšējās un ārējas vides analīzes teorētiskos aspektus, izpētīt kokapstrādes nozari, analizēt SIA „JM SLAT” iekšējo un ārējo vidi un izveidot SVID analīzi, tāpat ir nepieciešams noteikt SIA „JM SLAT” stiprās un vājās puses, iespējas un draudus, kā arī izvērtēt nākotnes perspektīvas.
Darba struktūra sastāv no anotācijām, ievada, 3 galvenajām nodaļām, apakšnodaļām, secinājumiem, priekšlikumiem, izmantoto avotu sarakstu.
Pirmā nodaļa ir darba teorētiskajā daļā, kurā ir aplūkoti un analizēti vairāku autoru viedokļi par uzņēmuma ārējās un iekšējās vides veidojošiem faktoriem un elementiem.
Otrajā nodaļā ir apskatīta SIA „JM SLAT” darbība, veikts vispārējs uzņēmuma darbības raksturojums.
Trešajā nodaļā tiek analizēta ārējā un iekšējā vide SIA „JM SLAT”, uzņēmumā un izveidota SVID analīze.
Nobeigumā ir sniegti secinājumi par darbā aplūkotajām problēmām un doti priekšlikumi uzņēmuma mārketinga un finanšu uzlabošanai, kas pēc autora domām varētu veicināt SIA „JM SLAT” attīstību. Par pētījuma avotiem izmantota speciālā literatūra, valsts statistikas dati, valdības lēmumi, MK noteikumi, ES Direktīvas, likumi, SIA JM Slat nepublicētie materiāli un interneta resursi. Bakalaura darbs sastāv no 73 lpp, darbā ir iekļauti 18 attēli, 11 tabulas.The topic of the bachelor’s thesis is “Analysis of the external and internal environment of the company JM SLAT Ltd.”. The examined company, JM SLAT is founded in 2003 in Varaklani region and its’ core business is woodworking.
The aim of the thesis is to examine and analyse the structure of the internal and external environment of JM SLAT on the basis of theoretical aspects, to identify the company’s strengths and weaknesses, and future perspectives, and to make conclusions and give proposals for the company’s development opportunities.
In order to achieve objectives of the thesis, it is necessary to identify theoretical aspects of the company’s internal and external environment analysis, to do a research of the woodworking industry, to analyse the internal and external environment of JM SLAT Ltd and to carry out a SWOT analysis. It is necessary to identify strengths, weaknesses, opportunities and threats, as well as to evaluate future perspectives of the company.
The bachelor’s thesis consists of 3 chapters.
The thesis structure consists of annotations, an introduction, 3 main chapters, subchapters, conclusions, proposals and bibliographical sources.
The first chapter is the theoretical part of the thesis, and it contains reviews and analysis of several authors’ opinions regarding the factors and elements that form the external and internal environment of a company.
The second chapter consists of JM SLAT Ltd. activity review and a general description of the company’s activities.
The third chapter is devoted to analysis of the external and internal environment of JM SLAT Ltd., and also includes the SWOT analysis.
The conclusion contains conclusions regarding the problems addressed in the thesis, and proposals for improvement of the company’s marketing and finances that as believed by the author could promote the development of JM SLAT Ltd. Sources that were used for the research include a special literature, national statistical data, governmental decisions, Cabinet regulations, EU Directives, legislation, unpublished materials of JM SLAT Ltd., and internet sources. The bachelor thesis consists of 73 pages, 18 pictures and 11 tables
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