13 research outputs found

    Bodger, Phoebe

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    View of the sweet pea field at Bodger seed farm in Gardena Valley, ca.1905

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    Photograph of a view of the sweet pea field at Bodger seed farm, 350 acres producing 27 tons of seeds, in Gardena Valley (later, Hawthorn, CA), ca.1905. The field is covered with tall-stalk flowers. Buildings are sparsely scattered across the landscape in the distance. Trees are visible in the distance. "The fields were put in as a tourist attraction." -- unknown author. Originally, the photograph was captioned as "View of the sweet pea field (possibly at Bodger seed farm), at Redondo Beach, looking east from the Redondo Hotel, ca.1904-1920"

    Influence of DNA Repair on Nonlinear Dose-Responses for Mutation

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    Recent evidence has challenged the default assumption that all DNA-reactive alkylating agents exhibit a linear dose-response. Emerging evidence suggests that the model alkylating agents methyl- and ethylmethanesulfonate and methylnitrosourea (MNU) and ethylnitrosourea observe a nonlinear dose-response with a no observed genotoxic effect level (NOGEL). Follow-up mechanistic studies are essential to understand the mechanism of cellular tolerance and biological relevance of such NOGELs. MNU is one of the most mutagenic simple alkylators. Therefore, understanding the mechanism of mutation induction, following low-dose MNU treatment, sets precedence for weaker mutagenic alkylating agents. Here, we tested MNU at 10-fold lower concentrations than a previous study and report a NOGEL of 0.0075μg/ml (72.8nM) in human lymphoblastoid cells, quantified through the hypoxanthine (guanine) phosphoribosyltransferase assay (OECD 476). Mechanistic studies reveal that the NOGEL is dependent upon repair of O6-methylguanine (O6MeG) by the suicide enzyme O6MeG-DNA methyltransferase (MGMT). Inactivation of MGMT sensitizes cells to MNU-induced mutagenesis and shifts the NOGEL to the left on the dose axis. © The Author 2013. Published by Oxford University Press on behalf of the Society of Toxicology. All rights reserved

    Investigation into laser re-melting of inconel 625 HVOF coating blended with WC

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    High velocity oxy-fuel (HVOF) spraying of Diamalloy 1005 powders mixed with WC particles onto steel (304) is considered and laser re-melting of the resulting coatings is examined. Laser re-melting process is modeled to determine the melt layer thickness while temperature increase is formulated using the Fourier heating law. The morphological and metallurgical analyses prior and post laser re-melting process are carried out using scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS). X-ray diffraction (XRD) technique is used to determine the residual stress developed in the coating while the analytical formulation is adopted to predict the residual stress levels at the coating base material interface. The indentation tests are carried out to determine the Young’s modulus and fracture toughness of the coating prior to laser re-melting. Corrosion resistance of coating is measured using potentiodynamic polarization technique prior and post laser treatment process. The predictions of the melt layer thickness are in good agreement with experimental results. The presence of WC particles modifies temperature rise and its gradient in the coating while affecting the Young’s modulus, residual stress levels, and fracture toughness of the coating. The differences in the thermal properties of Inconel 625 powders and WC particles result in formation of small size cellular structure through polyphase solidification. WC dissolution in the central region of the large polycrystalline cells is observed due to the loss of carbon through carbonic gas formation. The results of corrosion tests prevail that significant improvement of corrosion resistance can be achieved after laser treatment process

    ICTMC 2022: 6th International Clinical Trials Methodology Conference -- book of abstracts

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    ===Book of abstracts for ICTMC 2022: 6th International Clinical Trials and Methodology Conference=== Abstract authors: Dag Aarsland; Hanna Abraham; Jean Abraham; Janine Abrahamson; Juul Achten; Richard Adams; Joy Adamson; Ayoola Ademola; Bipin Adhikari; Amanda Adler; Fiona Adshead; Arnav Agarwal; Magda Aguiar; Elayne Ahern; Isma Ahmed; Norin Ahmed; Rashida Ahmed; Sadia Ahmed; Saiam Ahmed; Gemma Ainsworth; Jennifer Airlie; Olalekan Lee Aiyegbusi; Thankamma Ajithkumar; Murad Alam; Zaki Suleiman Albelbisi; Charlotte Albury; Sarah L Alderson; Sarah Alexander; Parvinder K Aley; Myzoon Ali; Raza Alikhan; Richard Allan; David Alldred; Christopher Allen; Saleh A Almazam; Mohammed Almekhlafi; Peter Almgren; Rustam Al-Shahi Salman; Jalemba Aluvaala; Annee Amjad; Alain Amstutz; Alain Amstuzt; Jenny Anderson; Nicola Anderson; Georgios Antoniou; Yoshitaka Aoki; Duncan Appelbe; John Apps; Catherine Ardundel; Alejandro Arenas-Pinto; Maria Aresu; Shabina Ariff; Jane Armitage; Lindsay Armstrong-Buisseret; Catherine Arundel; Theodoros N Arvanitis; Diptesh Aryal; Polly-anna Ashford; Ryan Ashford; Kate Ashton; Julie Ashworth; Amrita Athwal; Simon Aumônier; Kerry Avery; Kerry Avery; Kerry NL Avery; Salma Ayis; Augusto Azuara-Blanco; Danila Azzolina; Daphne Babalis; Michael R Backhouse; Matthew Bailey; Kenneth Baillie; Richard Baird; Amy Baker; Arabella Baker; Fouzi Bala; Saba P Balasubramanian; Ileana Baldi; Mandy Ballinger; Jonathan Bamber; Jenni Banks; Nick Bansback; Yihan Bao; Sarah Baos; Stuart Barber; Megan Barlow-Pay; Adam Barrett; Nicola Barrie; Heather Barrington; Y Kiera Bartlett; Elisa Basso; Jonathan Batchelor; Jonathan M Batchelor; Rachel Batchelor; Janine Bates; Philip M Bath; Leona Batten; Malcolm R Battin; Beth Beadle; Abi Beane; David J Beard; Lucy Beasant; Matthew Beasley; Susan Beatty; Jennifer Beckett; Jacqueline Beckhelling; Nicholas Beckley-Hoelscher; Alun Bedding; Emma Bedson; Carol Bedwell; Elizabeth Beech; Claire Beecher; Rabiah Begum; Hilary Bekker; Katie Belfield; Jennifer Bell; Lauren Bell; Elaine Beller; Chiara Bellucci; Jonathan Benger; Tina Bennett; Paola Berchialla; Jules Beresford-Dent; Jeffrey Berger; Sarah Berhane; Caitlin Bernard; Lisa Bero; Dan Berry; Wendy Bertram; Ashley Best; Catherine Best; Sara Betzhold; Scott Bevan; Judy Beveridge; Fenella Beynon; Vishal Bhatnagar; Amit Bhattarai; Sagida Bibi; Barbara E Bierer; Linda Biesty; Alice Biggane; Katie Biggs; Giovanni Biglino; Petra Bijsterveld; Lucinda Billingham; Laurent Jacques Billot; Megan Birchenall; Giles M Birchley; Katie Biscombe; Felicity L Bishop; Jon Bishop; Liam Bishop; Mark Bishton; Brigitte Bison; James Blackstone; Bronagh Blackwood; Pete Blair; Holly Blake; Pierre Blanchard; Marco H Blanker; Amanda Blatch-Jones; Jane Blazeby; Jane Blazeby; Jane M Blazeby; Natalie Blencowe; Natalie S Blencowe; Judith Bliss; Judith Bliss; Frank H Bloomfield; Anette Blümle; Keith Bodger; Chris Bojke; Jessica Bollen; W Bolton; Simon Bond; Alison Booth; Katie Booth; Catherine Borra; Andrew Bottomley; Stephanie Boughton; Liam Bourke; Elli Bourmpaki; Isabelle Boutron; Jack Bowden; Peter Bower; Hannah Bowers; Louise Bowman; Simon J Bowman; Sabine Braat; Karen Bracken; Mike Bradburn; Ellen Bradley; Helen Bradley; Lucy Bradshaw; Conan Brady; Marian C Brady; Kate Brain; Marie Braisher; Janice Branson; Claire Bratt; Amanda Bravery; Christopher D Brawley; Jack Brazier; Sophie Breeze; Alan Brennan; Cathy Brennan; Joseph Brennan; Paul Brennan; Moniek Nelleke Bresser; Gretchen Brewer; Sarah Bridges; Matthias Briel; Rachel Brierley; Kristian Brock; Kristian Brock; Kieran Bromley; Sue Brook; Cassandra Brookes; Jody Brookes; Matthew Brookes; Alanna Brown; Julia Brown; Louise Brown; Sarah Brown; Sarah T Brown; Cydney Louise Bruce; Hanne Bruhn; Hanne Bruhn; Dan Brunsdon; Hanna Bryant; Anne Buckle; Peter Buckle; Brian Buckley; Saraswati Budhathoki; Shyam S Sundar Budhathoki; Carol Bugge; Helen Bulbeck; Richard Bulbulia; Tiasha Burch; Abigail Burdon; Rochelle A Burgess; Nikita N Burke; Matthew Burnell; Eva Burnett; Stephanie Burnett; Lorna Burns; Steph Burns; Girvan Burnside; Matthew Bursnall; Matthew Burt; Christopher Burton; James O Burton; Bhavin Busa; Jason W Busse; Monica Busse; Christopher C Butler; Roeum Butt; Elaine W Butterly; Kate Button; Jacqueline Buxton; Anthony Byrne; Christie Cabral; Fay Cafferty; David Cairns; Joanne Calder; Melanie Calvert; Melanie J Calvert; Ailsa Cameron; Amy Campbell; John Campbell; Lisa Campbell; Marion Campbell; Mark Campbell; Michael J Campbell; Joanna Canham; Rebecca Cannings-John; Liberty Cantrell; Angela Cape; Taylor Capey; Heike Cappel-Porter; Alessandra Cardinali; Aaron Carlile; James R Carpenter; Ewan Carr; Rachel Carr; Rachel Margaret Carr; Neil Carragher; Kym Carter; Rufus Cartwright; Fergus Caskey; Marica Cassarino; Lana Castellucci; Mark Caulfield; Matthew Chaddock; Trudie Chalder; Anthony Chalmers; Mary Chambers; An-Wen Chan; Siddharthan Chandran; Ho Quang Chanh; Paul Channon; Caroline Chapman; Michael Chapman; Jeremy Chataway; Robin Chatters; Versha Cheed; Katie Chegwin; Chen Chen; Qianji Chen; Tao Chen; Ziming Chen; Zhaoxi Cheng; Svetlana (Sarah) Cherlin; Mary G Cherry; Victoria Chester; Mae Chester-Jones; May Chester-Jones; Stephen E Chick; Sarah Chinchen; Fay Chinnery; Anca Chis Ster; Anca Maria Chis Ster; Valentina Chminazzo; Babak Choodari-Oskooei; Avirup Chowdhury; Fatimah Jannat Chowdhury; Loraine Luise Chowdhury; Edward Christopher; David Chuter; Oriana Ciani; Silvia Cicconi; Alejandra Clark; Jane Clark; Joseph Clark; Laura Clark; Joanne Clarke; Michael J Clarke; Laura Clayton; Tim Clayton; Andrew Clegg; John Cleland; Clare Clement; Francesca Clemons; David Clifton; Jane Cloke; Madeleine Clout; Victoria Cluley; Victoria Cluley; Madeleine Cochet; Claire Cochran; Ann Cochrane; Sarah Cockayne; Emma Cockcroft; Frans Coenen; Taylor Coffey; Judith Cohen; Judith Cohen; Christina Cole; Joseph Samuel Colecchia; Courtney Coleman; Elizabeth Coleman; Nicholas Coleman; Charlotte Coles; Clive Collett; Laura Collett; Howard Collier; Howard Collier; Tim Collier; Jane Collingwood; Gary S Collins; Michael Collins; Michelle Collinson; Michelle Collinson; Philip Collis; Shuna Colville; Rosanna Irene Comoretto; Carmel Conefrey; Zak Connan; JP Connelly; Alex Connor; Elizabeth J Conroy; Abraham Contreras; Tom Conway; Adrian D Cook; Andrew Cook; Heather Cook; Jonathon A Cook; Graham S Cooke; Haley Coong; Cindy L Cooper; Clare Cooper; Joanne Cooper; Nicola Cooper; Andrew Copas; Bethan Copsey; Belen Corbacho; Anne Corbett; Victoria Cornelius; Neil Corrigan; Matthew L Costa; Sarah Cotterill; Seonaidh Cotton; Karen Coulman; Karen D Coulman; Louise Coutts; Trevor Cox; William J Cragg; Jennifer Craig; Katherine Craig; Sarah Craig; Zoe Craig; Jenny Craigen; Sophie Cramp; Denise Cranley; Tim Cranston; Anthea Craven; Esther Crawley; Siobhan Creanor; Siobhan Creanor; Catharine Cresswell; Rosanna Cretney; Sam Crevin; Charlie Crichton; Suzie Cro; Suzie Cro; Suzie Cro; Julie Croft; Susan Cromarty; Angela M Crook; James Crouch; Susanne Cruickshank; Samantha Cruz Rivera; Lucy Culliford; Oliver Cumming; Bonnie Cundill; David Cunningham; David Currow; Nigel Curtis; Valérie D’Acremont; Rachael Dagnall; Rachel S Dakin; Gillian Daly; Mandy Daly; Emma Dalyrimple; Rhian Daniel; Jane Daniels; John Dark; Huong Thi Thanh Dau; Wendy Daunt; Claire Davies; Elin Haf Davies; Gwyneth Davies; Hugh Davies; Jim Davies; Loretta Davies; Philippa Davies; Edward Davis; Michael J Davis; Evan Davy; Phoebe Dawe; Phoebe Kate Dawe; Annabel Dawson; Jeremy Dawson; Florence Day; Colin Dayan; Alimu Dayimu; Floriana De Angelis; Jennifer de Bayer; Johann S de Bono; Maria DF de la Maza; Anurika P De Silva; Anna De Simoni; Philip de Whalley; Annelise Decaria; Elizabeth Deja; Joanne Del Buono; Lorenzo Del Sorbo; Hannah Delaney; Edward Deller; Melanie Dembinsky; Nikolaos Demiris; Zsofia Demjen; Eugene Dempsey; Kayleigh Dempsey; Joanna Dennett; Alastair Denniston; Shiona Denton; Jayesh Desai; Riti Desai; Michael Desborough; Sandeep Rajiv Deshmukh; Lauren Desoysa; Declan Devane; Fitri A Dewi; Paula Dhiman; Sofia Dias; Carlos Diaz-Montana; Karla Diaz-Ordaz; Joseph Dib; Joseph Dibb; Andrew P Dickens; Jon Dickson; Andreas Dietz; Munya Dimairo; Amy Din; Van Dinh Khoa; McKenzie A Dirr; Caroline Dix; Padraig Dixon; Annemarie Docherty; James Dodd; Pete Dodd; Susanna Dodd; Susie Dodd; Laura Doherty; James Doidge; Arjen M Dondorp; Rachel Donegan; Gaohong Dong; Tam Dong Thi Hoai; Chloe Donohue; Jenny L Donovan; Peter Doran; Faye Doris; Anthony Dorling; Jon Dorling; Anisha Doshi; Georgina Dotchin; Sarah Douglas; Jessica Douglas-Pugh; Alan Downs; Heather Draper; Cheney Drew; Yuanhao Du; Weisong Duan; Kushupika Dube; Kate Duffus; Jennifer Dumbleton; Jo Dumville; Anne Duncan; Eilidh Duncan; Janet Dunn; Jennifer Dunsmore; Marie-Anne Durand; Brittany Dutton; Susan J Dutton; Huynh Thi Le Duyen; Tadeas Dvorak; Kerry Dwan; Lucy Dwyer; Helen Eborall; Saskia Eddy; Kate Edgar; Adrian Edwards; Clare Edwards; Danielle Edwards; Helen-Teresa Edwards; Suzanne Edwards; Aoife M Egan; Emily Eichenholtz; Adel El Feky; Adel El Feky; Nada Elbeltagi; Diana Elbourne; Sam Eldabe; Andrew Elders; Andrew Elders; Sandra Eldridge; Jack Elkes; Kamr Elkhafer; Daisy Elliott; Jim Elliott; Lucy Elliott; Rachel Ellison; Carolyn Ells; Beatrix Elsberger; Andrew Embleton-Thirsk; Jake Emmerson; Ryo Emoto; Richard Emsley; Coralie English; Holly Ennis; Hannah Ensor; Agnes Eordogh; Hanif Esmail; Hanif Esmail; Aude Espinasse; Alex Evans; Amy Evans; Helen Evans; Jeffry Evans; Judith Evans; Mererid Evans; Rachel Evans; Richard Evans; Ruth Evans; Colin C Everett; Colin Charles Everett; Hazel A Everitt; Colleen Ewart; Victoria Exley; Khaled Ezzedine; Caroline Fairhurst; Caroline Fairhurst; Caroline Fairhusrt; Corinne Faivre-Finn; Apostolos Fakis; Petra Falkenbach; Eddy Fan; Michael Farkouh; Kate Farley; Yama Farooq Mujadidi; Barbara Farquharson; Nicola Farrar; Amanda J Farrin; Saul N Faust; Stefano Fedele; David T Felson; Elaine SHuo Feng; Luda Feng; Shuo Feng; Niall Ferguson; Alison Fergusson; Lorna Fern; Catherine Fernandez; Conrad V Fernandez; Charles Festo; Linda Fiaschi; Ines Figueiredo; Simon Finfer; Sarah Finlayson; Laura Finneran; Elaine Finucane; Nick Firth; Claire Fitzsimons; Jenny Fleming; Emily Fletcher; Heidi Fletcher; Lydia Flett; Laura Flight; Penny Flohr; Barney Flower; Samantha Flynn; Ann-Kristin Folkerts; Caroline Fong; Gordon Forbes; Gordon Forbes; Alexander C Ford; Alexander C Ford; Deborah Ford; Deborah Ford; Colin Forde; Mark Forrest; Anne Forster; Anne Forster; Martin Forster; Bethany Foster; Stephanie Foster; James Fotheringham; George Fowler; Lisa Fox; Sonia Fox; Robbie Foy; Robbie Foy; Anne Francis; Nicolas Francis; AF Frangi; Elena Frangou; Marloes Franssen; Ceri Frayne; David P French; Peter Friend; Jonathan Frost; Greg Fuller; Olivia Fulton; Beth Fylan; Chris Gale; Chris P Gale; Beverley Gallacher; Marie Galligan; Rose Galvin; Sandra Galvin; Carol Gamble; Carrol Gamble; Carrol Gamble; Carrol Gambol; Frances Game; Pooja Gandhi; Urja Gandhi; Ying Gao; Herney A Garcia-Perdomo; Heidi Gardner; Peter Gardner; Kirsty Garfield; Joy Garfitt; Patrick Garfjeld-Roberts; Amit Garg; Alessio Gargaro; Elizabeth Gargon; Claire Garnett; Stefannie Garvin; Charlotte Gaskell; Sophie Gasson; David Gathara; Daisy Mary Gaunt; Piers Gaunt; Piers Gaunt; Gus Gazzard; Kelly Gee; Alpana Ghadge; Adrian Gheorghe; Nilabh Ghosh; Mujtaba Ghulam Farooq; Daniele Giacopelli; Nguyen Thi Giang; Diana M Gibb; Johnathan Gibb; Jonathan Gibb; Emily Gibson; Eleanor Gidman; Anna Gilbert; Stephanie Gilbert; Rachael Gilberts; David Gillespie; Katie Gillies; Katie Gillies; Alexa Gillman; Steven Gilmour; Alexia Giovanazzi; Athanasios Gkekas; Eleni Gkini; Efstathia Gkioni; Tracy R Glass; Viktoria Gloy; Ari Gnanasakthy; Maureen Godfrey; Megan Goff; Kimberley Goldsmith; Ewan Goligher; Robert Golub; Rachael Gooberman-Hill; Ruth Goodall; Ruth Goodall; Kirsteen Goodman; Elizabeth Goodwin; Victoria Goodwin; Michelle Abhayawardena Goonasekera; Gosala Gopalakrishnan; Adam L Gordon; Anthony C Gordon; Kathryn Gordon; Katie Gordon; Sarah Gorst; Sarah Gorst; Sarah L Gorst; Sarah Louise Gorst; Lesley Gosden; Unice Goshomi; Joe Gough; Beatriz Goulao; Beatriz Goulão; Doug Gould; Jenny Gould; Amit Goyal; Amit Goyal; Sheemu Goyal; Sandra Graca; Chris Graham; Sonia Gran; Richard Grant; Adam T Gray; Emma Gray; Laura Gray; Michael J Grayling; Heloise Greeff; Dan Green; Sophie Green; Melanie Greenland; Peter Greenstreet; Kate Greenwell; Michael Gregg; Dario Gregori; John Gregory; John Gregson; Akiko Greshon; Alastair Greystoke; Hannah Gribble; Alexandra N Griessbach; Richard Grieve; James Griffin; Xavier Griffin; Xavier Luke Griffin; Alys W Griffiths; Chris Griffiths; Gareth Griffiths; Jessica Griffiths; Anneke Grobler; Dmitry Gryaznov; Dmitry Gryaznov; Emilia Grycuk; Xiaorui Guan; Alessandro Guasconi; Martin Gulliford; Christina Guo; Samir Gupta; Elspeth Guthrie; Sarah Gwynne; Sushma Gyawali; Gill Gyte; David M Haas; Chris Habron; Elin Haf Davies; Suzanne Hagen; Stephen Hahn; Alexandra Haig; Andy Haines; Rachel Haines; Mahboobeh Haji Sadeghi; Julian Halcox; Sarah Halford; Andrew Hall; Emma Hall; Harry Hall; Louise H Hall; Nigel Hall; Sophie Hall; Freddie Hamdy; Sienna Hamer-Kiwacz; Tiffany Hamilton; Alison Hammond; Matt Hammond; Matthew Hammond; Natalie Hammonds; Rashan Haniffa; Bec Hanley; Peter Hanlon; Aminul Haque; Chris Harbron; Pollyanna Hardy; Nicola L Harman; Charlie Harper; James Harper; Steve Harper; Jessica Harris; Rosie Harris; Rosie Harris; Victoria Harris; David Harrison; Mark Harrison; Suzanne Hartley; Dan Harvey; Samar Hasan; Madiha Hashmi; Richard Hastings; Bruce Haughey; Diane Havard; Joanne Haviland; Olivia Hawksworth; Isobel Hawley; Alastair Hay; Rebecca Haydock; Rebecca Ann Haydock; Richard J Haynes; Chris Hayward; Lee Haywood; Audinga-dea Hazewinkel; Patricia Healy; Anna Heath; Paul Heath; Anne Heaven; Siew Wan Hee; Christie Heiberg; Jennifer Hellier; Toby Helliwell; Lars G Hemkens; Karla Hemming; Julie Hepburn; Trish Hepburn; Kate Herbert; Hibba Herieka; Rodolfo Hernandez; Merilyn Heuschkel; Catherine Hewitt; Nick Heywood; Helen Hickey; Helen Higgins; Steven Higgins; Juliet High; Ruchi Highman; Stephen Hiles; Crispin Hiley; Nicholas Hilken; Elizabeth Hill; Michael D Hill; Louise Hiller; Robert J Hinchliffe; Samantha Hinsley; Samantha Hinsley; Ian Hirsch; Shuyen Ho; Hai Ho Bich; Chanh Ho Quang; Luu Hoai Bao Tran; FD Richard Hobbs; Richard Hobbs; Richard F Hobbs; Pat Hoddinott; Renate Hodge; Sheila Hodgson; Clare Hodkinson; Christin Hoffmann; Ameer Steven-Jorg Hohlfeld; Sinead Holden; Peter Holding; Fiona Holland; Gail Holland; William Hollingworth; Ivana Holloway; Søren Holm; Chris Holmes; Jane Holmes; Chris Holsinger; Victoria Homer; Karenza Hood; Sally Hopewell; Della Hopkins; Emma Hopkins; Valerie Hopkins; Peter Horby; Adele Jayne Horobin; Judith Horrocks; Danielle Horton Taylor; Jeremy Horwood; Anower Hossain; Reyhaneh Hosseini; Lesley A Houghton; Daniel Howdon; Donna Howe; Laura Howells; Nick Howells; Asbjørn Hróbjartsson; Shao-Fan Hsieh; Eric Huber; Robert Huddart; Cara Hudson; Ella Hudson; Jemma Hudson; Marie Hudson; Arfon Hughes; Jacki Hughes; Karen Hughes; Kate Hughes; Kathy Hughes; Rachael Hughes; Sarah E Hughes; Claire Hulme; Isla Humphreys; Amanda Hunn; Beverley Hunt; Jessica Hunt; Andrew Hunter; Tim Hurley; Chris Hurt; Nusrat Husain; Samantha Husbands; Jamilla Hussain; Arishay Hussaini; Hayley A Hutchings; Ann Hutchinson; David Hutton; David Hutton; Richard Huxtable; Nguyen Quang Huy; Vu Ngo Thanh Huyen; Julie Huynh; Laura Huynh; Duyen Huynh Thi Le; Trieu Huynh Trung; Claire Hyder; Belinda Ianson; Saïd Ibeggazene; Fowzia Ibrahim; Mais Iflaifel; Clare Iles; Heather Iles-Smith; Elizabeth Ingram; Jenny Ingram; John R Ingram; Karen Innes; Gulnaz Iqbal; Talia Isaacs; Jonathan CS Ives; Andrew J Pollard; Aimee Jackson; Richard Jackson; Timothy L Jackson; Tracy Jackson; Pamela Jacobsen; Richard Jacques; Richard Jacques; Thomas Jaki; Rajiv Jalan; Zahra Jamal; Elizabeth C James; Nicholas D James; Sophie James; Stefanie James; Leila Janani; Damien Janecki; Perrine Janiaud; Jan Jansen; Sena Jawad; Hari Jayaraman; Mark Jayes; Gregor BE Jemec; Isobel Jenkins; Rhys Jenkins; Michael D Jenkinson; Mathew Jenner; Christopher Jennison; Brett Jepson; Marcus Jepson; Christina Jerosch-Herold; Clare Jess; Chen Ji; Qiuyang Jia; Tao Jiang; Xinyao Jin; Jessica Johansson; Nevin John; Graham Johnson; Miriam J Johnson; Nicholas A Johnson; Philip Johnson; Samantha Johnson; Zoe Johnson; Kate Jolly; Ashley Jones; Benjamin G Jones; Katherine Jones; Megan Jones; Sadie Jones; Terry Jones; Kelvin P Jordan; Shivam Joshi; Katherine Joyce; Katie Joyce; Patrick Julier; Stephen Julious; Shyma Jundi; Edmund Juszczak; Parvinder K Aley; Julia Kaal; Brennan C Kahan; Martin Kaiser; Elke Kalbe; Delordson Kallon; Maeve Kalusche; Paul Kamudoni; Shravan Kandula; Joseph Kane; Richard Kaplan; Richard S Kaplan; Konstantinos Karampatsas; Alexia Karantana; Waseem Karsan; Jamlick Karumbi; Benjamin Kasenda; Shamim Kazmi-Stokes; Sharon Kean; Anna Kearney; Rebecca Kearney; Rohna Kearney; Ada Keding; Katie Keen; Katie Keen; David J Keene; Eimear Kelly; Fiona Kelly; Sarah Kelly; Jessica Kendall; Anthony Kendrick; Nicholas Alexander Kennedy; Lorcan Kenny; Merryn Kent; Evelyne Kestelyn; Aisha Khan; Iftekhar Khan; Naila Khan; Sheeba Khan; Kamlesh Khunti; Vincent Kibet; Shannon Kidd; Andrew Kightley; Lucy Kilburn; Lucy Kilburn; Tuomas P Kilpeläinen; Nicola Kime; Irina Kinchin; Andrew King; Anni King; Anthony King; Diana King; Pritaporn Kingkaew; Nigel Kirby; Amanda Kirkham; Jamie Kirkham; Jamie J Kirkham; Katie Kirkham; John Kirkpatrick; Laura Kirton; Cliona Kirwan; Jana Kirwan; Katharina Klatte; Peter Knapp; Simon Knight; Matthew Kobetic; Ruwanthi Kolamunnage-Dona; Jorma Komulainen; Elena Koneska; Anthony Kong; Lucy Kornblith; Sarah Koskei; Kasia Kostyrka-Allchorne; Jan Kottner; Daphne Kounali; Matthew G Krebs; Tamara Kredo; Ashma Krishan; Biza Kroese; Thomas Kuhnt; Ashok Kumar; Ravi Kumar; Tracey-Lea Laba; Emma Laing; Hamish Laing; Olli Lainiala; Ranjit Lall; Ngoc Hong Bao Lam; Teresa Lambe; Tiina Lamberg; Penny Lambert; Catherine Lamont Robinson; Gillian Lancaster; Gillian A Lancaster; Sabine Landau; Martin Landray; Athene Lane; Athene Lane; Athene J Lane; Emma Lane; Corrado Lanera; Alexandra Lang; Peter Langdon; Hélène Langet; Kirsty Lanyon; Daniel Frank P Larkin; Kerry Larkin; T Lassila; Mandy Lau; Tina Lavender; Martin Law; Patrick Lawler; Louisa Lawrie; Anna Lawson; John Lawson; Sarah Lawton; Sarah A Lawton; Alison Layton; Rajeka Lazarus; Chan Ning Lee; Chee Khoon Lee; Ellen Lee; Hopin Lee; Kim May Lee; Shing Lee; Eric Leifer; Paul Leighton; Robert Lendrum; Iracema Leroi; Bess LeRoy; Alex Lewis; Amanda Lewis; Jen Lewis; Martyn Lewis; Mickey Lewis; Rebecca Lewis; Steff Lewis; Jim Lewsey; Val Leyland; Linke Li; Tianjing Li; Wenyue Li; Eric Lim; Wei Shen Lim; Frank Lin; Mark Linch; Robert Lindsay; Louise Linsell; Chris Linsley; Kim Linton; Nasrin Lipi; Steven Lister; Paul Little; Paul Little; Jia Liu; Rong Liu; Xiaoxuan Liu; Xinxue Liu; James Lloyd; Lisa Lloyd; Wang Pok Lo; Trudie Lobban; Phillipa Logan; Szimonetta Lohner; Szimonetta Lohner; Noemi Lois; Eleni Loizidou; Alice Longe; Pei Loo Ow; Andres Lopes; Juanita Suzanne Lopez; Janet M Lord; Jodie Lord; Ava Lorenc; Giulia Lorenzoni; Sharon B Love; Patricia Lucas; Fiona V Lugg-widger; Farah Lunat; Mark Lunt; Duo Lv; Lisa Macaulay; Kateryna MacConaill; Rhiannon Macefield; Rhiannon Macefield; Andrea Machin; Tim Machin; Kathryn Machray; Terry Mackie; Graeme MacLennan; Graeme MacLennan; Malcolm R Macleod; Una Macleod; Iain Macpherson; Daniel Maddock; Karen Madronal; Marion M Mafham; Laura Magee; Nirosha Mahendraratnam; Alisha Maher; Rachel Maishman; Christian D Mallen; Mary Mancini; Adrian Mander; Thubeena Manickavasagar; Erika Mann; Georgina Manning; Anita Mansouri; Anita Mansouri; Anthony Muchai Manyara; Rejina Mariam-verghis; Ioana R Marian; Sarah Markham; Laura Marsden; Laura E Marsden; Kevin Marsh; Lucy Marsh; Andrea Marshall; Lynley Marshall; Tony Marson; Adam Martin; Jonathan Martin; Jacqueline Martin-Kerry; Clara Martins de Barros; Honorati Masanja; Alexina Mason; Clare Mason; Ellen Mason; James Mason; Lindsey Masters; R Mathew; Maura Mathews; Sigeyuki Matsui; Astrid Mattes; Cameron Matthew; Olivia Matthews; Ruth Matthews; Karen Matvienko-Sikar; Phil Mawson; Graziella Mazza; David McAllister; David A McAllister; Amy McAndrew; Daniel McAuley; Leanne McCabe; Sarah McClure; Terry McCormack; Gareth Mccray; Peter Mcculloch; Catriona McDaid; Lorraine McDonagh; Cliona McDowell; Stuart McKechnie; Micheal M McKenna; Mairead Mckenzie; Yvonne McKenzie; Michelle McKinley; Dean McMillan; Christel McMullan; Angus McNair; Angus GK McNair; Carolyn McNamara; Rachel McNamara; Emma McNaught; Cindy McShea; Gillean Mead; Angela M Meade; Garry Meakin; Garry Meakin; Hisham Mehanna; Shireen Meher; Shireen Meher; Jennifer Mehew; Gautam Mehta; Samir Mehta; Alan Melcher; GJ Melendez-Torres; Kyle Melin; Katie Mellor; Lynn Melone; Bijoy K Menon; Tom Menzies; Rebecca Mercieca-Bebber; Elizabeth Merrall; Dominik Mertz; Andy Metcalf; Andrew Metcalfe; Chris Metcalfe; Grace Mhalu; Iris Mhlanga; Jahanara Miah; Gary Middleton; Lee Middleton; Elizabeth Miles; Marie Miller; Nicola Mills; Tracey Mills; Christopher P Millward; Michael Millward; Nguyet Minh Nguyen; Lam Minh Yen; Haitham Mirghani; Katy Mironov; Aziza Mirza; Alex Mitchell; Caroline Mitchell; Eleanor J Mitchell; James Mitchell; Sandra Mitchell; Tracy Mitchell; Dipayan Mitra; Tempei Miyaji; Abdallah Mkopi; Catherine Moakes; Katherine Moar; Neena Modi; Thirimon Moe-Byrne; David Moher; David Moher; Eleanor J Molloy; Barbara Molony-Oates; Joao Monteiro; Alan A Montgomery; Gwenllian Moody; Gwenllian Moody; Cara Mooney; Keith Moore; Sally Moore; Giova

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    PAGE FOUR DAILY PALO ALTO TIMES, FRIDAY. OCTOBER I, IOU. •"Daily paloHlto Iiiiice ■faraia ai *h»ti4 iIim roatttr. MAIL RIB SCRIPT ION RATE. ll's.al.l- in iduticl „ [>',ie'«i.t Ran Oa# Y-«- I. • aMs "■ i!. ii. Im Wttk, , On* Mr!' , T-aa Wash , A-tdrt-M all 'nmmuflksilona tu THE DAILY .*IMES. Palo AIM. CaL Sew. tt ■Si* Alts at *"*anf«d pepv>t say*! amtli soli-It*-** THE TIMES m i t»"iJ* f-sr tV* ■x-i"l**M ef cuittsspd-si t ** *igtm4 hfttMlm nam, *t Ih* METEOROLOGICAL i im- - l..i., i-i Tor 1,'iii'iti'n.: Grwrr.-tll* clear, moderately warm. .,i.,.n- at noon today; Barometer *KI Ini-tie*, iheniHmietpr AH degrM*-. bjrgronettgf |wr cent, weather clear, wind calm. Ttie IiIrIi | *■»**.*. uri* or air wa*. ren. tr..l In New I .. : lind (In- Miwini; Although wmker and of le*» extent It continue-, to check -tomewltat tbe prtsgTr—- of Hi.' ir*.[.|,..i Morrn whtrb waa ..nn.,I In tbe Ohio valley this morning. Aa the r*-nil of this atomi the weather |« Mill rainy or un-et* tied from the Mi- ■ i- - i>i'. river to Hie Ai:..iii.. itoaat, n'ad from the Oraat Ijik.*- to the fiuir of Mexico. Tlte storm seeiui io lie i*wing enertrj, mul Will |. .■ ■ quietly on tlie Atlantic . ocean —I— ll i-» de'ayetl lon*X •enoogh t» Join lbs* -t**ni> now tn* rjuwdng in enrr-*x in SaAkatchwan. Te-ii|H i.iiu,- i,4i,,,l.i\. Kept. Jill: Haxfmnm Hit (two year*, ago ***■ minimum IH (two years iigo *■" Cooked Food Sale Set for Tomorrow Ladies' Auxiliary of St. Thomas Aquinas Church Will Serve Prepared Dainties The Ladles Auxiliary of St. Thorn mm Aquinas Church will hold a food sale tomorrow tn the vacant store of the Masonic Temple. The doors will open at 9:30 In the morning and remain open until evening. Palo Alto iwople are familiar with the cooking skill displaced by the ladles. Ko need to cook, you can buy everything from soup to nuts for your Sunday dinner l*opuIar prices. _ PALO ALTO CALENDAR Friday, lst Haymond F. West memorial lecture by Rev. Dr. Charles Lewis Slattery. rector draco Church. New York. North transept Memorial Church, ft p. m . Saturday. 2d Eight o'clock sharp. morning prayers, organ gsllery* 4:30 p. m.. half hour of music: Memorial Church. Elder A. E. Place, pastor of the Seventh Day Adventlst Church, San Jose, will give the Bible study on lhe sanctuary and Us relation to pro|*ec>. The public Is cordis]!? Invited. 411 Waver ley street, 3 p.m. Cooked food sale hy |,adle* Auxll- lary of St. Thomas Aquinas Church In Masonic building. 1:34 to C* »»♦■*-♦ s-e-s* ON THE CAMPUS Fourteen sophomores were chosen Wednesday night by Coach Arthur Cyril for Ihe roles of the second- year play. "Hobby Hurnlt." to be presented November 6th in Assembly Halt. Three minor parts, two for women and one male role are still uadedded. Tbe student council calls the attention of men of the university to the ruling by the university conference against any form of jeering or unseemly demonstration on the occasion of Pan-Hellenic pledge dsy, "The Running Fight" to Be Played at Varsity Theatre Tonight Paramount Pictures Present Thrilling Story With AU- Star Cut Sentiment of students at the University of California, as refected la Student Opinion, tbe new open forum, denounces the arbitrary metb> ods displayed by Slue and Gold athletic Isadora In their switch from Hughy to American football. Dr. H. II. Stolx was elected president of the i-">f .Hub at a meeting held in tbe vestry Wednesday night OfMH'KRATl. E SKLLIN'G PLAN Five thousand Ontario fruitgrowers this season are co-operating wllh retail merrhants. Year after year these fruitgrowers have been fared with the question of the proper distribution of their fruit, and manv complstnta hsve arisen due to certain localities receiving on over- Supply, while oilier and larger sections of tbe country have been without sufficient quantities to meet the deni: ids of the consumer. ■This year these fruitgrowers got together and subscribed Jointly to a /campaign of advertising, the object of whlrh was simply to urge consumers to see their fruit dealer and have him make provision for them bv securing fruit In advance The fruit dealer himself was provided with the same Information through the trade press. This plan has worked so icressfully that consumers nil over Canada ure todav able to secure plentiful supplies of all fruits, and the retailer has worked so successfully that con sumers are today able to secure plentiful supplies of all fruit*, nnd the retailer has increased his business, his fruit In many instance-* being sold In advance of its arrival at hla store, Consul S. 8. Johnson. Kingston, Ontario, Canada. That plans' sre now under way to arrsnge a series of games for preparatory school aod collegiate champions with Hughy clubs of Australia and New Zealand, was the statement given out yesterday by Dr. Frank Angell or the faculty athletic committee. With Swimming Coach* Brand»t*n acting In the capacity of master of ceremonies, the newly-opened plung** will be officially dedicated today and tomorrow morning, when the twlce- iHiK'pnned Interrlaa* swimming meet will be pulled off. .Sunday, .'t.i Congregational Church - Preach-j Ing service at 11 a. in,, sermon hyl Die Itev. Bryant C. Preston of Peta-i I ulna. Young People's service at Tilt p. m. In the church parlor. The business meeting of the will lie held tn the church Tuesday. October Mb, at Spurnsen was Nanwrnmittal. Tbe Bev. W. Wllllama. ln his "Personal Hemtntacences of C H Spur- s**eon.** tella an anecdote concerning the great preacher as a smoker. Aome gentleman wrote i,. Mr. Rpurgeon'. ■■>> log: "He in.,! tieftnl bt- smoked and could uot believe it was true. Would Mr. Bpurgeon write and tell If it really was por The reply was sent as follows: -Desr -—, | cultlvste my flowers and burn my weeds. Your* truly. C H. Bpurgeon" annual church purlor ", "ii p tn. Meniorlul Church—11 o'ctotk. di- x III.-. services; Doctor Slattery of 11 race Church. New York, will preach: anthem. '*! Am Alpha and Omega'' IStainert*'. Miss Helen Keg- ley soloist: solo. "Teach Me to Pray" tJewliii. I., die MrCormlrk. Organ recital. 1 p. m. I'liltarian Church -Sunday School at 9.4... Sermon by Professor Hriino I'iuvii..:.-. ..1 ..j.-. i "Why I Am a .rnltiirlan." It a, in . The Palo Alto Symphnny Society practice, high school studio, mem* tiers please bring racks, 3 p. m. Pslo Alto Truth Center—Kvenlng ■crvlce Address hy William Far- well of San Jose. Public Invited Music. Voluntary offering, a p. m. (-Monday, till Kxecottve board meeting of the Parenl-Teai-her .\nsoclnllon at the home of .Mrs. It W. Slmklns at 3 p. in Plant and bulb exchange for October 15th meeting to be considered. All district snd other committee chairmen invited. Toe-day, (Hit l-ecttire hy Mrs. Winifred Stoner snd "Wonder Child" In Haptlst Church at 3 o'clock. Wedne-vUy. fltli Woman's Club business meeting: 2.30. program led by Mrs. Jennie V. Cannon. 3 p. m BROOKS' BREAD Famed for its Quality Superfine Special Butternut Whole Wheat Raisin Bohemian Rye .* - BROOKS' BAKERY Phone 750 " Quality, Variety and Service As ahakespsars 6a.d. "Sweat Will Shakespeare's" Influence is still with us, snd many of tbe phrases which be iited hsve become part of our Istigurttfe. Among these phrases an: "Bag and baggage." "deed as a doornail." "bli i.r nil-**." "love Is blind," "selling foi a m.ii,*.'" "wide world," "taai and ,.«■• <•.' '"na consider- ed trifles." "w<-.tv.j** ..*»:' "familiarity breeds contempts | ;i i.lng up excuses.*' "mfiery makes -4:™!!,*--,* liedfel- lows," **to ttoot." "shot, and loug of It," "dnncliii* ittmdaili ft.', "getting even," "birds of , feintier," "■Greek to me," "that's Hut." 'packing a Jury>" "mother wit." "Lilted with klmlneas." "mom" fur silent "ill wind tbat blows no good," "wild goose chase." "*acan*- ctowb,** "row of pins," "firs voce." "give snd take." "sold." "yoor cake la doogh." Shakespeare was the first author to use tho words "man In tbe moon" or mention the potato or use the term "eyesore" for annoyauce In a Japan*** School. In **A Wanderer'a Trail** A. I*. Bodger. the author, says: "lo Tokyo I gained my living aa an English teacher. This tssk of teaching English lu Japan ts not a very difficult one. It la. however, a rather tiring occupation. The MM qualification necessary to tact. Discipline In Japanese schools is very lax. It Is no exaggeration to aay that the student virtually rules tbe acbooL Ills power Is ridiculously great Should a clsas dislike a teacher they either boycott hlm or tbey boldly proceed en masse to tbs acbool authorities and demand bis dismissal. And the almost inevitable re- ault la tbe teacher's dismissal! To tbe authorities ttie only guaranty of the efficiency or a teacher la a full claea- n-.ni. Needless to mention. I wss an efficient, fur my claaa room waa always full. Tbst is why I ssy tbe only quail flcatloii needed waa tact." Wendarful Llnan Bi-tMeh-M. A. O. Bunnell of Dansvllle has In bla possession s petition which was clrcu- Isted In hla village In 1878 snd signed by well known people, remarks tbe L'tlca Press. Tho petition appesla to a prominent clttsen to wear his linen breeches. It seems that this gentleman bad a pair of linen breeches, and *v- cry time be wore them ram felL In 1878 than wsa a long cootlnosd drought tn Dsnsvllle and thecaabouta. and tba cttiaena dertdsd to appsal to Mattbe-w McCartney to wear his linen breecbas "In order that tbe parcbed up earth, low streams, dry walls and cisterns may bs replenished with a bountiful supply of water." air* McCartney gractoualy consented to don bis tinea breeches, and on tbe original paper In Mr. Bunnell's possess loo ia thla Indorsement: "Italn commenced felling tba same Bight" Making It Ct**r. "Now. my good man. before wt start out lu your machine let us understand each other perfectly." -weti. wbst is ur i am not destmus of seeing now fait you csn drive this csr; It Is tbe scenery I wish to see-"—I»etrolt Free Pre** Klovating. Wigg—The man who loves s woman •ant help being elevated. Wagg— And (be msn who loves motV than one ts apt to be sent np too.—Philadelphia Record. To pity dlstreas Is but human; to relieve It Is godlike.-Mann. "The Runotng Fight.'' whtch will be staged tonight st ths Varsity Theater, besides being sn extraordinarily wetl-fllmed production yf an Interesting story, hss s cast of exceptional quality. Violet Homing you know, of course, The youngest star on Broad' way Is Indeed a beautiful and attractive girt and an actress of qusl it :■ aoisLexperience. t'ri.ler the management of tbe late Charles Prohman. wben Mlsa Homing was but twelve, ahe played "Wendy" In Peter Pan. After this she was cast as Rebecca In "Rebecca of Sunnybrook Fsrtn." Following this came many more notable parts untl] at the age of fifteen she became Albert Chevalier's leading lady in "Daddy Du Ford " Th. came "The Fox." "The Deep Purple." "Disrsell." In which she was associated with George Arils* Miss Hemlng's successes are almost too numerous to mention. Then there is Thnrlow Bergen. During hla brilliant stage career he has played at being governor In tot: stales, nnd congressman representing three of them. Mr. Bergen was s lawyer at nineteen. Possibly this accounts for the fact that be makes such a splendid governor in "Tbe Running Fight." Robert Cain aa district attorney ■lao an actor of vast experience. having' played in "The Misleading !-ady." "He Comes Cp Smiling." (Joodnlght. Nurse*." "The Deep Ptir- le" and several others. W\ T. Carlton, of International IKTBtic fame, needs no Introduction lo the public except io the field of moving pictures. - He ftpptsara in The Running Fight" Ss Colonel Morehead the lawyer. Robert Cumralngs. too, hss bad a atage experience which makes him aliisble member of tho cssl, having been in many original casts and nany feature pictures. FOR RENT. LOST For Rent—Furnished t-room house and garage. Apply owner. Ill Lytton svenue S-8-tf For Rent—One room for two, and on* single room, to quiet people Call 342 Homer avenue. Phone 72&. SVs-tf saluting th* Quarter Dad*a. Io reaponae to an inquiry sa to why officer* and men of tbe navy "salute the deck" and tivtllana remove tbelr bats wben going aboard s naval vessel It msy be said that though com- 1u01.lv called a "salute to the deck." tha astute tn question is rcslly s salute to the flag. For Instance, at night on reaching tbe quarter deck or upon leaving lt no saluto is retjulred, as tbs flag ls. of course, not flying. Tb* fsct that this salute is rendered upon reaching tbe quarter deck from below or when coming on botrd and upon leaving tbe quarter deck, as wben leaving tbs ship. Is probably responsible for Its ha till-* tieen koowu as a aatote lo tbe deck; but as bas been stated. It Is really a salute to the flag. Man ■ ho uld when rendering tt stop, stand erect sod face the lag. ■■ Philadelphia. Press. ■loimon'i Ch**rfuln*sa. "1 shall never forgot Mr. 8t*v*naon." said a rsptaln wbo commanded a ship on which Robert Lout* Stevenson ssU- .-1 "The ship hsd broken ber shaft sod was delayed. He cbsersd *very- :--1y up by telling funny stortas that wen better coming offhand from his lips than most literary men could writs If they worked orer tbem for weeks. ll.. knew, too, tbst It was only a question of a ahort time bsfor* be would dl* of consumption and tbst be could nev*r again go bom* for mora than a bri*f viiit. It was simply wooderful what a difference that on* man mads among tbe paaaengers, and I guess almost all of us would gladly spend the time to mske port under sail, with machinery disabled. If w* could bar* a Stevenson aboard." MISCELLANEOUS. Hoard snd room. 126: board. 910: s»ntlemen preferred- 2l» Ramona treat. a-16-tf Palo Altsns sre showing spprecls- tlon. Frisco prices. Solares. cleaner. IBS I'nlverslty. nr. Cowp*r. Ph. 20. 1 9-21-lm SHORTHAND. TYPEWRITING AND M1MKOORAPHINO. Mra F. M.Whlt- mer. 334 Homer ave. Phone '■■■ ' * »-!!-lm t'HIMNKT SWEEP—A man who knows how. Permanent sddrsas. Walter'c Cigar Store. Phone *H0X. *-21-lm• Circle barber shop snd Frank's igar store. 108 Circle, now open. -.-crythlng up to date. 9-13-lm* If you need a map of Pslo Atto snowing th* locstlon of churn-"*, schools, the cfty ball, the watai- aorkai tbs big tree, tbe station, tb* names of all the streets, it con be pro'iired st The Times offic* printed 01 cardboard at r. c*nt« a copy: nrlnted on bond psp*r to be folded for mailing, two copls* for *■ cents. Times office. For Ssle—Gentle family horse; _ uat be sold at once. Jack Fslt, Redwood City. Box ".7 1 »-28-6t* For Salt—scratch tablets, good paper, padded. Two slxss. 3x5. two for l* cents; 4x1. three for 10 ceots. For Rent—Modern apt*., completely furnished: quiet, no children. Tbs Lytton. 481 Lytton av*. Phone 736X svi-a For Rent—Large rurnlshed front room In private family. Gentleman only. 4S7 Bryant 9-25-ot For Rant—Business place at 427 High street. 9-1-lt, For Rtnt—305 Cowper St., corner Evoret ave. completely furnished sunny house. Enqulr* 84< Bryant * 9-ta-U For (.ease—To thoroughly reliable man. flv* acres with four-room house and bam on Atherton are., near Menlo. 118 Slocum A Si ration. 10-1-If FOR SALE. For Sate—Sorrel mare, harnes* and wagon, cheap. Call 7t» Homer Phone ««2K *-30->ta For Sal*—Sixty-five bead of hogs. twenty good brood sows, fine young team of borsaa. Phone 738. Weeks' Poultry Ranch. Palo Alto. H-tO-lf For sale, blsck walnut parlor furniture and single bedroom set of five piece*. French plate-glass mirror x7, wicker rockers, lounge, cblns. hricabrar. at private residence, 414 Bryant, corner Lytton. 10-1-8P-— Adrt. For Sale—Flemish Glsnt and heavy-weight Belgian barer, breeding stock. Ph. 494K. O. S. Yoder. a-30-«t# For Sale—Friers and broilers. Phone 709K a-SO-St Pbone for pure Jersey milk. Cows are tested. Phone mitY. J Domt.y 1-27-1 ra» For Sale— Seven-passenger Oar- ford touring csr In good condition Enquire *.(>♦,Unlveraity avenu*. Ixwt—Flat black para* containing smalt change also fonMeai clover pin with pearls. Retsm Time* offic* ls-l-lt Lost—Gold wreath pin set with pearls. Finder please return to 52R Channlng snd receive reward. 9-30-Ct yotmD ■rerybody talks about SoUme Why? Clean suit return same day. 4S2 University, near Cowper. Pb. 20. 9-21-lm PROFMSIONAL NOTARY PUBLIC. DICY A. BAUGH Notary Public 257 University Ave. HAIRDRESSING. Shampooing Maakwriag and Hair Work. Combings Made tp MISS E. CHRISTOFFERSON Vlaiwg B*dg.. 398 ralvarst-tr Ave PHllS'K an. For Sale—Smalt dealt pads at 20 cents a doien. while they last: site about 2x'l Inches. Apply Times offlce. WANTED Wanted—Any kind of housework, by d«y or hour, by competent rell- sble woman Phone T.39L 9*30-*>t* l.ei'« get acquainted with our new method. Solares- cleaning, hat re* modeling, etc. |0| 1,'ntr. Phone 20. 9-31-tm Wanted—Gardening or any Mu! of laboring work Phone 63SK. 9-24-tf Waoted—House-cleaning, half day tn the mornlng'oc. < noking after .*. o'clock, by Japanesst* boy. 720 Ra* mom. Ph 626X T Mlsakl. l<M-6t* Student will do any kind of work after scbooi hours for bosrd snd room. Address L. W.. Times offlce. 10-1-tf Wanted - *f o rent smsll unfur- Isbed cottage with improvements. hy three adults, quiet neighborhood: best of references. State rent and full particulars P. O Box 501. P. A. 10-1-St- Wanted—Work by gsrdener caring for private places: good worker. steady; r«fs. Q. C . 199 Sherman at Mayfield- lO-l-St' Wsnted—Cooking in small family by Japanese girt. Mra. Akashl. 733 Ramona street Phon* 705K. 9-27-«f laundry to Uke home. Flrst-claa**. work. Rates reasonable. Mending free. Work called for and delivered Phone 53IX. Mrs. Jenkins, 180 Forest 9-27-St Wanted — Housework, wishing, ironing or garden work by day bv Japanese boy. Address C. Tootl. Times offlce. 9-3-lm* ■Wsnted---Work by the day wash ing, cleaning. Ironing, sewing cook Ing. Mra. A. Bodltn. Phone S32K Sewtng. mending, care Invalids, help at socials or tight housework. Mrs. Melody. Phone C38K. 9-20-tf Wanted-—Competent woman for general work and to assist in care of children. Beferenees required. Phone 644. 9-23-tf LOWENA D1FANI (.fa.l.w.r <■*.,;..«..: iBstitulcot Hair CaHar* Hair ...*•>.£,-; Mir,kts..s€ Pat-UI T»r«Mi«Dt Cotmbtat* Milt sp Statp Ir*a1*ntnl a »pe-i»T*r ^ CHIROPRACTOR ARK VOl* SICK OR I \MK ' Don't despair until you bsvs tried Chiropractic Spinal Adjustment. No drugs or knife. Free examination. Lady attendant J. THORNLEY. D. C. I'nlr. Hotel. Circle. Ph. «SOK. INSURANCE Fire |4fe Mil ■!.,;. V ■ ..lei.t Uahillty M. .hi. We represent old reliable companteo Slocum & Stratlon lot LytKm Aveaoe. Palo Alto* 1 1 H, DI'RKN. 11. M. PIANO AND HARMONY Htudjo H-J4 Kiner*on Htreet. Phone 757X, Mrs. Bibby-Brown will resume vocal teaching after September 1st. mi,.I,., ;||| Kierett Avenue Itione mil, -, . E. ROYAL FLINT Piano aad Harmony l**ipilg Coasvetrvatory Diploma. studio MO Homer Aveane. Itione 17*8. Tbe timber School of Music Mrs. Mar-a K. Kimber. director. .to.1 Lytton Avenue. Circular oa appHcatloa. PI..m- 7S». MRS. P. O.HUNDLEY Teacher of Piano ha" opened ber studio at l*.l 4JV4 Portwt Ave. Itione IIMY KH.VKST T. MARtTH -OntiOratrat lenity Co'**-j- L«—J*)>) Teacher of Violin aad (Wl.. t>'»engaged mornings Moo., Wed.. Friday, some evenings. PhosM* I'alo Alto M17 it., la-* Ml Palo Alto Nursery Frank R. Hills. Proprietor; Gtowm^s of Cat Fowers awd Look'a'Herel When >*>u want that electric beater instated, don't for- get to phone U.j-sCA S.. wi-;-.

    High versus low positive end-expiratory pressure during general anaesthesia for open abdominal surgery (PROVHILO trial): a multicentre randomised controlled trial

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    Background The role of positive end-expiratory pressure in mechanical ventilation during general anaesthesia for surgery remains uncertain. Levels of pressure higher than 0 cm H2O might protect against postoperative pulmonary complications but could also cause intraoperative circulatory depression and lung injury from overdistension. We tested the hypothesis that a high level of positive end-expiratory pressure with recruitment manoeuvres protects against postoperative pulmonary complications in patients at risk of complications who are receiving mechanical ventilation with low tidal volumes during general anaesthesia for open abdominal surgery.Methods In this randomised controlled trial at 30 centres in Europe and North and South America, we recruited 900 patients at risk for postoperative pulmonary complications who were planned for open abdominal surgery under general anaesthesia and ventilation at tidal volumes of 8 mL/kg. We randomly allocated patients to either a high level of positive end-expiratory pressure (12 cm H2O) with recruitment manoeuvres (higher PEEP group) or a low level of pressure (<= 2 cm H2O) without recruitment manoeuvres (lower PEEP group). We used a centralised computer-generated randomisation system. Patients and outcome assessors were masked to the intervention. Primary endpoint was a composite of postoperative pulmonary complications by postoperative day 5. Analysis was by intention-to-treat. The study is registered at Controlled-Trials. com, number ISRCTN70332574.Findings From February, 2011, to January, 2013, 447 patients were randomly allocated to the higher PEEP group and 453 to the lower PEEP group. Six patients were excluded from the analysis, four because they withdrew consent and two for violation of inclusion criteria. Median levels of positive end-expiratory pressure were 12 cm H2O (IQR 12-12) in the higher PEEP group and 2 cm H2O (0-2) in the lower PEEP group. Postoperative pulmonary complications were reported in 174 (40%) of 445 patients in the higher PEEP group versus 172 (39%) of 449 patients in the lower PEEP group (relative risk 1.01; 95% CI 0.86-1.20; p = 0.86). Compared with patients in the lower PEEP group, those in the higher PEEP group developed intraoperative hypotension and needed more vasoactive drugs.Interpretation A strategy with a high level of positive end-expiratory pressure and recruitment manoeuvres during open abdominal surgery does not protect against postoperative pulmonary complications. An intraoperative protective ventilation strategy should include a low tidal volume and low positive end-expiratory pressure, without recruitment manoeuvres

    Effect of a perioperative, cardiac output-guided hemodynamic therapy algorithm on outcomes following major gastrointestinal surgery: a randomized clinical trial and systematic review

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    Importance: small trials suggest that postoperative outcomes may be improved by the use of cardiac output monitoring to guide administration of intravenous fluid and inotropic drugs as part of a hemodynamic therapy algorithm.Objective: to evaluate the clinical effectiveness of a perioperative, cardiac output–guided hemodynamic therapy algorithm.Design, setting, and participants: OPTIMISE was a pragmatic, multicenter, randomized, observer-blinded trial of 734 high-risk patients aged 50 years or older undergoing major gastrointestinal surgery at 17 acute care hospitals in the United Kingdom. An updated systematic review and meta-analysis were also conducted including randomized trials published from 1966 to February 2014.Interventions: patients were randomly assigned to a cardiac output–guided hemodynamic therapy algorithm for intravenous fluid and inotrope (dopexamine) infusion during and 6 hours following surgery (n=368) or to usual care (n=366).Main outcomes and measures: the primary outcome was a composite of predefined 30-day moderate or major complications and mortality. Secondary outcomes were morbidity on day 7; infection, critical care–free days, and all-cause mortality at 30 days; all-cause mortality at 180 days; and length of hospital stay.Results: baseline patient characteristics, clinical care, and volumes of intravenous fluid were similar between groups. Care was nonadherent to the allocated treatment for less than 10% of patients in each group. The primary outcome occurred in 36.6% of intervention and 43.4% of usual care participants (relative risk [RR], 0.84 [95% CI, 0.71-1.01]; absolute risk reduction, 6.8% [95% CI, ?0.3% to 13.9%]; P?=?.07). There was no significant difference between groups for any secondary outcomes. Five intervention patients (1.4%) experienced cardiovascular serious adverse events within 24 hours compared with none in the usual care group. Findings of the meta-analysis of 38 trials, including data from this study, suggest that the intervention is associated with fewer complications (intervention, 488/1548 [31.5%] vs control, 614/1476 [41.6%]; RR, 0.77 [95% CI, 0.71-0.83]) and a nonsignificant reduction in hospital, 28-day, or 30-day mortality (intervention, 159/3215 deaths [4.9%] vs control, 206/3160 deaths [6.5%]; RR, 0.82 [95% CI, 0.67-1.01]) and mortality at longest follow-up (intervention, 267/3215 deaths [8.3%] vs control, 327/3160 deaths [10.3%]; RR, 0.86 [95% CI, 0.74-1.00]).Conclusions and relevance: in a randomized trial of high-risk patients undergoing major gastrointestinal surgery, use of a cardiac output–guided hemodynamic therapy algorithm compared with usual care did not reduce a composite outcome of complications and 30-day mortality. However, inclusion of these data in an updated meta-analysis indicates that the intervention was associated with a reduction in complication rate

    Association of intraoperative end-tidal CO2 levels with postoperative outcomes: a patient-level analysis of two randomised clinical trials

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    Background: The relationship between intraoperative end-tidal CO2 (etCO2) levels and postoperative outcomes remains unclear. We conducted a post hoc analysis of two randomised trials in adults undergoing major surgery under general anaesthesia. Methods: We re-analysed individual participant data comparing high or low positive end-expiratory pressure with low tidal volume intraoperative ventilation using a merged database derived from two randomised trials in non-obese (PROVHILO: ISRCTN70332574) and obese (PROBESE: NCT02148692) patients. The exposure of interest was low etCO2 (<4.7 kPa) vs normal-high etCO2 (≥4.7 kPa). The primary outcome was postoperative pulmonary complications within 5 days. A time-weighted etCO2 analysis and propensity score matching were also performed to adjust for confounding. Results: Of 2793 participants, 891 (29.4%; 52% female) had low etCO2, compared with 1972/2793 (70.6%; 65% female) participants with normal-high etCO2. Compared with participants with normal-high etCO2, higher minute volumes (normalised to body weight) were delivered in participants with low etCO2. Postoperative pulmonary complications developed in 278/821 (34%) participants with low etCO2, compared with 462/1972 (23%) participants who had normal-high etCO2 (adjusted hazard ratio, 1.3; 95% confidence interval, 1.1–1.6; P<0.001). The time-weighted analysis showed an inverse linear relationship between the mean etCO2 and postoperative pulmonary complications, which was also confirmed by propensity matching. Conclusions: Low etCO2 occurs often during intraoperative ventilation and is associated with a higher rate of PPCs. The etCO2 level has an inverse dose-dependent relationship with postoperative pulmonary complications. Clinical trial registration: NCT05550181

    Individual and combined effects of chemical and mechanical power on postoperative pulmonary complications: a secondary analysis of the REPEAT study

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    Introduction: Intra-operative supplemental oxygen and mechanical ventilation expose the lungs to potentially injurious energy. This can be quantified as 'chemical power' and 'mechanical power', respectively. In this study, we sought to determine if intra-operative chemical and mechanical power, individually and/or in combination, are associated with postoperative pulmonary complications. Methods: Using an individual patient data analysis of three randomised clinical trials of intra-operative ventilation, we summarised intra-operative chemical and mechanical power using time-weighted averages. We evaluated the association between intra-operative chemical and mechanical power and a collapsed composite of postoperative pulmonary complications using multivariable logistic regression to estimate the odds ratios related to the effect of 1 J.min-1 increase in chemical or mechanical power with adjustment for demographic and intra-operative characteristics. We also included an interaction term to assess for potential synergistic effects of chemical and mechanical power on postoperative pulmonary complications. Results: Of 3837 patients recruited to three individual trials, 2492 with full datasets were included in the analysis. Intra-operative time-weighted average (SD) chemical power was 10.2 (3.9) J.min-1 and mechanical power was 10.5 (4.4) J.min-1. An increase of 1 J.min-1 in chemical power was associated with 8% higher odds of postoperative pulmonary complications (OR 1.08, 95%CI 1.05-1.10, p &lt; 0.001), while the same increase in mechanical power raised odds by 5% (OR 1.05, 95%CI 1.02-1.08, p = 0.003). We did not find evidence of a significant interaction between chemical and mechanical power (p = 0.40), suggestive of an additive rather than synergistic effect on postoperative pulmonary complications. Discussion: Both chemical and mechanical power are independently associated with postoperative pulmonary complications. Further work is required to determine causality
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