4,388 research outputs found
Letter from Duncan Phillips, Phllips Memorial Gallery, to John Sloan, May 31, 1928.
No full text1 leaf (single sided)Letter from Duncan Phillips, Phllips Memorial Gallery, to John Sloan, May 31, 1928
Letter from Duncan Phillips, Phllips Memorial Gallery, to John Sloan, May 31, 1928.
No full text1 leaf (single sided)Letter from Duncan Phillips, Phllips Memorial Gallery, to John Sloan, May 31, 1928
Classico e moderno: sullo sguardo di Duncan Phillips
No full textLo scritto introduce la mostra dedicata a una scelta di opere della raccolta Phillips di Washington tenutasi al Palazzo delle Esposizioni di Roma nel 2015 e descrive lo svilupparsi degli interessi collezionistici di Duncan Phillips fra gli anni Venti e gli anni Cinquanta del XX secol
Quince Duncan Moodie
No full textLiterary Encyclopedia entry on Costa Rican author Quince Duncan Moodi
Also By The Same Author: AKTiveAuthor, a Citation Graph Approach to Name Disambiguation
No full textThe desire for definitive data and the semantic web drive for inference over heterogeneous data sources requires co-reference resolution to be performed on those data. In particular, name disambiguation is required to allow accurate publication lists, citation counts and impact measures to be determined. This paper describes a graph-based approach to author disambiguation on large-scale citation networks. Using self-citation, co-authorship and document source analyses, AKTiveAuthor clusters papers, achieving precision of 0.997 and recall of 0.818 over a test group of eight surname clusters
Southern Thailand: from conflict to negotiations?
No full textSummary: In this Analysis, University of Leeds professor Duncan McCargo argues that the recent Malaysian-backed Southern Thai peace initiative has now run into some serious problems. He argues that despite its various shortcomings the initiative is still worthy of support, since it has gained far more traction that any previous attempts to address the decade-long insurgency. Thailand needs to maintain focus on the southern conflict despite its current preoccupation with a national-level political crisis that threatens to topple the government of Yingluck Shinawatra.
Key findings
The conflict in Southern Thailand is one of Asia’s most serious insurgencies, with over 6,000 dead over the last 10 years.
The Malaysian government sponsored negotiations represents the best hope for reaching a political settlement and bringing peace to the region.
However, both sides need to show greater commitment to the negotiations, introducing new structures and procedures
The Family Story of Alissa Duncan
No full textThe Family History of
Alissa A. Duncan
24 April 2016
Alissa Anne Duncan authored this family history as part of the course requirements for HIST 550/700 Your Family in History offered online in Spring 2016 and was submitted to the Pittsburg State University Digital Commons. Please contact the author directly with any questions or comments: [email protected]
David Duncan Wallace Papers - Accession 333
No full textThe David Duncan Wallace Papers consist of microfiche copies of the original David D. Wallace family papers, 1866-1951, SCHS 1233.00 held at the South Carolina Historical Society. David Duncan Wallace (1874-1951) was a Professor of History at Wofford College from 1899 through 1947 and was the author of the three volume set titled, History of South Carolina published in 1934. He is considered one of the foremost historians in State. The papers consist of his correspondence, research notes, clippings, and published and unpublished manuscripts related to his publications and areas of research. Also, included is some ephemera and other items.https://digitalcommons.winthrop.edu/manuscriptcollection_findingaids/1417/thumbnail.jp
Dynamics and utility of cell-free DNA release following radiotherapy in prostate cancer and non-small cell lung cancer
No full textINTRODUCTION:
The tissue-of-origin of plasma cell-free DNA (cfDNA) can be determined by methylation analysis and circulating tumour DNA identified by next-generation sequencing (NGS). To evaluate the dynamics of cfDNA during radical radiotherapy, total cfDNA was quantified in patients undergoing radiotherapy for prostate and lung cancer; samples from a sub-cohort underwent methylation analysis and NGS.
METHODS:
Analysis of blood plasma cfDNA was carried out on samples from patients receiving stereotactic ablative body radiotherapy for non-small cell lung cancer (n=39), conventional radiotherapy for prostate cancer (n=59), and stereotactic radiotherapy for localised prostate cancer (n=19). Radiotherapy doses delivered to healthy tissues, survival outcomes and treatment toxicity outcomes were evaluated. Samples from three lung patients underwent NGS, and samples from 11 prostate patients underwent methylation analysis. In the lung cancer patients, radiation-induced lung injury (RILI) was measured on follow-up computed tomography scans and correlation analysis carried out between the dose received by normal lung and the relative volume of RILI. Prostate cancer patients completed a questionnaire evaluating their attitudes to the risk of treatment toxicity.
RESULTS:
Total cfDNA concentration was not predictive of treatment outcomes. Somatic lung cancer-associated mutations were detected by NGS of cfDNA in 2/3 patients. The dose delivered to lung tissue correlated with the volume of RILI on post-treatment CTs. In the prostate cancer cohort, methylation analysis showed an increase in prostate tumour-derived cfDNA signal during radiotherapy in all 11 prostate cancer patients included in the sub-cohort. There was an increase in bladder and rectum-derived cfDNA signal in 2/5 and 1/5 patients respectively. The treatment questionnaire in prostate patients indicated their unwillingness to accept more severe side effects, regardless of the theoretical chance of cure.
DISCUSSION:
CfDNA released during prostate radiotherapy may provide a means of detecting tumour and normal tissue response to radiotherapy. Sequencing analysis of cfDNA can identify tumour-related mutations in patients with early-stage lung cancer. Dosimetric data and analysis of cfDNA may help predict the development of RILI, though studies in larger numbers are needed. The risk of post-treatment toxicity is an important consideration for patients
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